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Terazosin hydrochloride

Terazosin hydrochloride Structure
Terazosin hydrochloride structure
CAS No.
63074-08-8
Chemical Name:
Terazosin hydrochloride
Synonyms
Itrin;HYTRIN;Hitrin;Vicard;Blavin;Dysalfa;Flotrin;Heitrin;Hytrine;Olyster
CBNumber:
CB9285510
Molecular Formula:
C19H26ClN5O4
Molecular Weight:
423.9
MDL Number:
MFCD00467965
MOL File:
63074-08-8.mol
Last updated:2024-11-19 15:53:33
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Terazosin hydrochloride Properties

Melting point 261-263°C
storage temp. Inert atmosphere,2-8°C
solubility H2O: 25 mg/mL
form powder
color white to off-white
Water Solubility Soluble in water at 20mg/ml. Also soluble in methanol or ethanol.
Stability Stable for 2 years as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
CAS DataBase Reference 63074-08-8(CAS DataBase Reference)
NCI Dictionary of Cancer Terms terazosin hydrochloride
FDA UNII 8QOP8Z9955

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P501
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  TK8044925
NFPA 704
0
2 0

Terazosin hydrochloride price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T4680 Terazosin hydrochloride ≥98% (TLC), powder 63074-08-8 50mg $211 2024-03-01 Buy
Sigma-Aldrich T4680 Terazosin hydrochloride ≥98% (TLC), powder 63074-08-8 250mg $368 2024-03-01 Buy
Alfa Aesar J62055 Terazosin hydrochloride 99+% 63074-08-8 50mg $131 2023-06-20 Buy
Cayman Chemical 20216 Terazosin (hydrochloride) ≥98% 63074-08-8 100mg $110 2024-03-01 Buy
Cayman Chemical 20216 Terazosin (hydrochloride) ≥98% 63074-08-8 250mg $218 2024-03-01 Buy
Product number Packaging Price Buy
T4680 50mg $211 Buy
T4680 250mg $368 Buy
J62055 50mg $131 Buy
20216 100mg $110 Buy
20216 250mg $218 Buy

Terazosin hydrochloride Chemical Properties,Uses,Production

Description

Terazosin hydrochloride is a highly water-soluble antihypertensive agent with a structure and profile closely related to that of prazosin.

Originator

Abbott (USA)

Uses

An α-1-adrenergicblocker related to prazosin.

Uses

Hytrin (Abbott).

Uses

Terazosin hydrochloride has been used for orthogonality and similarity analysis using reversed-phase chromatographic studies5. Furthermore, terazosin has also been used for the evaluation of chemometric techniques to determine orthogonality and similarity in chromatographic methods6.

brand name

Terazosin is INN and BAN;HEITRIN.

General Description

Terazosin hydrochloride, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(tetrahydro-2-furoyl)piperazine monohydrochloride (Hytrin), is a structuralcongener of prazosin hydrochloride. It possessessimilar selective properties of specifically inhibiting 1-adrenergic receptors. The drug is slightly less potent thanprazosin hydrochloride. Terazosin hydrochloride has a halflifeof approximately 12 hours, which is much longer thanthat of prazosin. This lends itself to a once-daily dose tocontrol hypertension in many patients.

Biological Activity

α 1 - and α 2B -adrenoceptor antagonist (K i values are 3.3, 0.7, 1.1, 7.7, 1510 and 78.2 nM for α 1A , α 1B , α 1D , α 2B , α 2A and α 2C receptors respectively). Antihypertensive following oral or intravenous administration in vivo .

Biochem/physiol Actions

α1-adrenoceptor antagonist.

storage

Store at RT

References

References/Citations 1) Hancock et al. (1995), Actions of terazosin and its enantiomers at subtypes of alpha-1 and alpha-2 adrenoceptors in vitro; Recept. Signal Transduct. Res., 15 863 2) Kyncl et al. (1986), Pharmacology of terazosin; Am. J. Med., 80 12 3) Shionoiri et al. (1994), Long-term therapy with terazosin may improve glucose and lipid metabolism in hypertensives: a multicenter prospective study; Am. J. Med. Sci., 307 Suppl 1 S91 4) Pan et al. (2003), Identification of apoptotic and antiangiogenic activities of terazosin in human prostate cancer and endothelial cells; J. Urol., 169 724 5) Chen et al. (2015), Terazosin activates Pgk1 and HSP90 to promote stress resistance; Nat. Chem. Biol., 11 19

Terazosin hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Terazosin

Terazosin hydrochloride Suppliers

Global( 249)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32957 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29884 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28172 58
HubeiwidelychemicaltechnologyCo.,Ltd 		18627774460 faith@widelychemical.com CHINA 742 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49374 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21142 58
Zhengzhou Alfa Chemical Co.,Ltd 		+8618530059196 sale04@alfachem.cn China 13503 58
SIMAGCHEM CORP 		+86-13806087780 sale@simagchem.com China 17365 58
WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD 		+8615377521700 wangwendy93@gmail.com China 868 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Hubei Jusheng Technology Co.,Ltd. 		58
HubeiwidelychemicaltechnologyCo.,Ltd 		58
Chongqing Chemdad Co., Ltd 		58
CONIER CHEM AND PHARMA LIMITED 		58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58
Zhengzhou Alfa Chemical Co.,Ltd 		58
SIMAGCHEM CORP 		58
WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD 		58

View Lastest Price from Terazosin hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Terazosin hydrochloride pictures 2024-11-19 Terazosin hydrochloride
63074-08-8
 US $37.00-82.00 / mg 99.91% 10g TargetMol Chemicals Inc.
Terazosin hydrochloride pictures 2024-11-19 Terazosin hydrochloride
63074-08-8
 US $37.00-82.00 / mg 99.91% 10g TargetMol Chemicals Inc.
Terazosin hydrochloride pictures 2024-11-14 Terazosin hydrochloride
63074-08-8
 US $121.00 / KG 1KG 99% 200T Baoji Guokang Bio-Technology Co., Ltd.

Terazosin hydrochloride Spectrum

Terazosin hydrochloride(63074-08-8)1HNMR

63074-08-8(Terazosin hydrochloride)Related Search:

TERAZOSIN HYDROCHLORIDE DIHYDRATE Cetirizine dihydrochloride Telmisartan 4-Amino-6,7-dimethoxyquinazoline Terazosin
Quinazoline Terazosin hydrochloride TERAZOSIN HYDROCHLORIDE DIHYDRATEIMP. O (EP): 1,4-BIS[(TETRAHYDROFURAN-2-YL)CARBONYL]PIPERAZINE TERAZOSIN HYDROCHLORIDE DIHYDRATEIMP. N (EP): 1-[[(2RS)-TETRAHYDROFURAN-2-YL]CARBONYL]PIPERAZINE TERAZOSIN HYDROCHLORIDE DIHYDRATEIMP. K (EP) AS HYDROCHLORIDE:PRAZOSIN HYDROCHLORIDE
TERAZOSIN HYDROCHLORIDE MONOHYDRATE TERAZOSIN HYDROCHLORIDE DIHYDRATEIMP. M (EP): 1,4-BIS(FURAN-2-YLCARBONYL)PIPERAZINE (R)-(+)-TERAZOSIN HYDROCHLORIDE DIHYDRATE Terazosin hydrochloride, anhydrous TERAZOSIN HYDROCHLORIDE DIHYDRATEIMP. L (EP): 1-(FURAN-2-YLCARBONYL)-PIPERAZINE
TERAZOSIN HYDROCHLORIDE DIHYDRATEIMP. C (EP): 6,7-DIMETHOXY-2-(PIPERAZIN-1-YL)QUINAZOLIN-4-AMINE TERAZOSIN HYDROCHLORIDE DIHYDRATEIMP. A (EP): 2-CHLORO-6,7-DIMETHOXYQUINAZOLIN-4-AMINE

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Tarazosin Hydrochloride [4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)piperazin-1-yl]-tetrahydrofuran-2-yl-methanone hydrochloride Methanone,[4-(4-aMino-6,7-diMethoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)-,hydrochloride (1:1) abbott-45975 piperazine,1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)c TERAZOSIN HCL TERAZOSIN HYDROCHLORIDE TERAZOSIN MONOHYDROCHLORIDE HYTRIN 1-(4-AMINO-6,7-DIMETHOXY-2-QUINAZOLINYL)-4-[(TETRAHYDRO-2-FURANYL)CARBONXYL]PIPERAZINE, HYDROCHLORIDE 1-[4-AMINO-6,7-DIMETHOXY-2-QUINAZOLINYL]-4-([TETRAHYDRO-2-FURANYL]CARBONYL) PIPERAZINE HYDROCHLORIDE Tetrachlorphthalsureanhydrid s-(+-2-alaninol) Terazosin monohydrochloride anhydrous Terazosin hydrochloride anhydride [4-(4-AMINO-6,7-DIMETHOXY-QUINAZOLIN-2-YL)PIPERAZIN-1-YL]-OXOLAN-2-YL-METHANONE Tetrazosin hydrochloride 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(tetrahydro-2-furoyl)piperazine monohydrochloride 2-[4-(Tetrahydro-2-furoyl)-piperazine]-4-amino-6,7-dimethoxyquinazoline-hydrochloride Dysalfa Flotrin Heitrin Hitrin Hytracin Hytrine Itrin Olyster Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]-, monohydrochloride (9CI) Teralfa Tructum Vasocard Vasomet Vicard 6,7-dimethoxy-2-[4-(oxolane-2-carbonyl)piperazin-1-yl]quinazolin-4-amine hydrochloride [4-(4-amino-6,7-dimethoxy-2-quinazolin-3-iumyl)-1-piperazinyl]-[(2R)-2-oxolanyl]methanone Zayasel Fosfomic Blavin Terazosin hydrochloride USP/EP/BP 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)4-[(tetrahydro-2-fur... Terazosin hydrochlorideTerazosin hydrochloride Terazosin HydrochlorideQ: What is Terazosin Hydrochloride Q: What is the CAS Number of Terazosin Hydrochloride Q: What is the storage condition of Terazosin Hydrochloride Q: What are the applications of Terazosin Hydrochloride Terazocin HCl Terazosin hydrochloride salt 4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl](tetrahydrofuran-2-yl)methanone 63074-08-8 63950-64-7 C19H25N5O4HCl C19H25N5O4ClH Terazosin (intermediate of levofloxacin) Adrenoceptor Pharmaceutical