Anti-XTH2
- CAS No.
- Chemical Name:
- Anti-XTH2
- Synonyms
- Anti-APE2;Anti-XTH2;Anti-APEXL2;Anti-APEX2 antibody produced in mouse;Anti-APEX2 antibody produced in rabbit;Anti-APEX nuclease (apurinic/apyrimidinic endonuclease) 2
- CBNumber:
- CB92886243
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Anti-XTH2 price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB1400507 | Anti-APEX2 antibody produced in mouse IgG fraction of antiserum, buffered aqueous solution | 50μg | $524 | 2024-03-01 | Buy | |
| Sigma-Aldrich | HPA048577 | Anti-APEX2 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody | 100μL | $580 | 2024-03-01 | Buy |
Anti-XTH2 Chemical Properties,Uses,Production
Uses
All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.
The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .
General Description
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5′ to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair (BER). (provided by RefSeq)
Biochem/physiol Actions
Apex2 (apurinic/apyrimidinic endodeoxyribonuclease 2) maintains the function and integrity of mitochondrial DNA. It possesses a robust 3′?5′ exonuclease activity. Ape2 helps to delete adenine opposite to 8-oxoG in DNA.
Anti-XTH2 Preparation Products And Raw materials
Raw materials
Preparation Products
Anti-XTH2 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Merck KGaA | 21-20338288 | ordercn@merckgroup.com | China | 292394 | 58 |
| Supplier | Advantage |
|---|---|
| Merck KGaA | 58 |