Sericin Bombyx mori (silkworm)

General Description

Sericin is a protein derived from the silkworm cocoon and has a number of beneficial characteristics for culturing mammalian cells. It has cryoprotective properties that allow for replacement of FBS in cryopreservation media. 1% sericin (w/v) along with 0.5% (w/v) maltose, 0.3% (w/v) proline, 0.3% (w/v) glutamine and 10% DMSO is comparable to 90% FBS and 10% DMSO. Furthermore, sericin can act as a FBS replacement in cell culture and stimulate cell growth and in certain situations, inhibit cell death.