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Sulfamerazine sodium

CAS No.
127-58-2
Chemical Name:
Sulfamerazine sodium
Synonyms
Nsc226823;solumedine;sulfamerazine sodium;SODIUM SULFAMERAZINE;sodiumsulphamerazine;solublesulfamerazine;Pyrimidine sodium sulfa;SULFAMERAZINE SODIUM SALT;SulfadimidineSodium,Pharma;Sulfamerazine sodium USP/EP/BP
CBNumber:
CB9289260
Molecular Formula:
C11H13N4NaO2S
Molecular Weight:
288.3
MDL Number:
MFCD00068332
MOL File:
127-58-2.mol
MSDS File:
SDS
Last updated:2024-12-18 14:15:30

Sulfamerazine sodium Properties

RTECS WP0760000
storage temp. Store at -20°C
solubility Soluble in DMSO
form Powder
Water Solubility Soluble in DMSO or water
CAS DataBase Reference 127-58-2(CAS DataBase Reference)
FDA UNII JOV4UJY07O
EPA Substance Registry System Benzenesulfonamide, 4-amino-N-(4-methyl-2-pyrimidinyl)-, monosodium salt (127-58-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302+H332-H315-H319
Precautionary statements  P261-P264-P301+P312-P302+P352-P304+P340+P312-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  20/22-36/38-36/37/38
Safety Statements  7-24-45-36-26
WGK Germany  3
TSCA  Yes
NFPA 704
0
3 0

Sulfamerazine sodium price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S0800 Sulfamerazine sodium salt 127-58-2 250g $162 2024-03-01 Buy
Alfa Aesar J66717 Sulfamerazine sodium salt 127-58-2 250g $150 2024-03-01 Buy
Cayman Chemical 23380 Sulfamerazine (sodium salt) ≥98% 127-58-2 10g $32 2024-03-01 Buy
Cayman Chemical 23380 Sulfamerazine (sodium salt) ≥98% 127-58-2 50g $56 2024-03-01 Buy
Cayman Chemical 23380 Sulfamerazine (sodium salt) ≥98% 127-58-2 100g $78 2024-03-01 Buy
Product number Packaging Price Buy
S0800 250g $162 Buy
J66717 250g $150 Buy
23380 10g $32 Buy
23380 50g $56 Buy
23380 100g $78 Buy

Sulfamerazine sodium Chemical Properties,Uses,Production

Description

Sulfamerazine is a sulfonamide antibiotic. It inhibits bacterial carbonic anhydrase by ~20% at a concentration of 500 μM. In vivo, sulfamerazine (500 mg/L) reduces severity of peribronchitis and inhibits cilia-associated respiratory Bacillus colonization in mice. It also prevents death of Toxoplasma-infected mice. Sulfonamide class antibiotics, of which sulfamerazine is a member, are bacteriostatic and inhibit bacterial synthesis of dihydrofolic acid by competing with 4-aminobenzoic acid for binding to dihydropteroate synthase. Formulations containing sulfamerazine have been used for the treatment of pneumonia and typhoid fever.

Uses

Involved in characterization of chirosan membranes for the transport of drugs1,2,3

brand name

Bio hubber simple;Cremo-merazine;Debnal m;Mebacid;Neotrizine;Peccocode;Septosil;Spanbolet ii;Tersulpha;Trisulfaminic;Trisulpha.

World Health Organization (WHO)

Sulfamerazine sodium, a sulfonamide anti-infective agent, was introduced several decades ago for the treatment of bacterial infections. The importance of sulfonamides has subsequently decreased as a result of increasing resistance and their replacement by antibiotics which are generally more active and less toxic. The sulfonamides are known to cause serious adverse effects such as renal toxicity, sometimes fatal exfoliative dermatitis and erythema multiforma and dangerous adverse reactions affecting blood formation such as agranulocytosis and haemolytic or aplastic anaemia. Sulfamerazine is still used in some countries usually in combination with other sulfonamides.

Safety Profile

Moderately toxic by ingestion, subcutaneous, intraperitoneal, and intravenous routes. When heated to decomposition it emits toxic fumes of SOx, NOx, and Na2O.

Sulfamerazine sodium Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 132)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618092446649 sarah@tnjone.com China 1143 58
Hebei Zhuanglai Chemical Trading Co Ltd
+86-16264648883 +86-16264648883 niki@zlchemi.com China 2789 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29880 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293 sales@sdzschem.com China 2930 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49374 58
SIMAGCHEM CORP
+86-13806087780 sale@simagchem.com China 17365 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58

View Lastest Price from Sulfamerazine sodium manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
 Sulfamerazine Sodium pictures 2024-12-23 Sulfamerazine Sodium
127-58-2
US $150.00 / kg 1kg 99% 500kg Hebei Zhuanglai Chemical Trading Co Ltd
Sulfamerazine sodium salt pictures 2024-10-24 Sulfamerazine sodium salt
127-58-2
US $195.00 / g 10g TargetMol Chemicals Inc.
Sulfamerazine Sodium pictures 2024-04-05 Sulfamerazine Sodium
127-58-2
US $0.00 / kg 1kg 99% 1000kg Shaanxi TNJONE Pharmaceutical Co., Ltd
solumedine SODIUM SULFAMERAZINE sulfamerazine sodium SULFAMERAZINE SODIUM SALT SULFAMERAZINE, SODIUM SALT MONOHYDRATE monosodium 2-sulfanilamido-4-methylpyrimidine 2-sulfanilamido-4-methylpyrimidine sodium salt 4-AMINO-N-[4-METHYL-2-PYRIMIDINYL]-BENZENESULFONAMIDE SODIUM SALT 4-methyl-2-sulfanilamidopyrimidine sodium salt 4-amino-n-(4-methyl-2-pyrimidinyl)-benzenesulfonamidmonosodiumsalt n(sup1)-(4-methyl-2-pyrimidinyl)sulfanilamidesodiumsalt n(sup1)-(4-methyl-2-pyrimidinyl)-sulfanilamidmonosodiumsalt sodiumsulphamerazine solublesulfamerazine SULFAMERAZINE SODIUM(SM1-NA)(NDC:56631-1715) Pyrimidine sodium sulfa SulfadimidineSodium,Pharma Benzenesulfonamide, 4-amino-N-(4-methyl-2-pyrimidinyl)-, monosodium salt Nsc226823 (4-aminophenyl)sulfonyl-(4-methylpyrimidin-2-yl)azanide sodium,(4-aminophenyl)sulfonyl-(4-methylpyrimidin-2-yl)azanide Sulfamerazine sodium USP/EP/BP 4-amino-N-(4-methyl-2-pyrimidinyl)-benzenesulfonamide, monosodium salt 127-58-2 C11H11N4NaO2S C11H11N4O2SNa Heterocyclic Building Blocks Pyrimidines Building Blocks Building Blocks C9 to C11 Chemical Synthesis Heterocyclic Building Blocks Pyrimidines