G2/mitotic-specific cyclin-B1
- CAS No.
- Chemical Name:
- G2/mitotic-specific cyclin-B1
- Synonyms
- CCNB;POLD;CYCB;CDC2;CCNA1;CCN-2;CCNB1;CCNB1-RS1;Human CCNA1 Protein, His Tag;G2/mitotic-specific cyclin-B1
- CBNumber:
- CB92895966
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00243104
- MOL File:
- Mol file
G2/mitotic-specific cyclin-B1 price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SRP5009 | CDK1/CyclinB1, active, GST tagged human PRECISIO? Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution | 10μG | $516 | 2023-06-20 | Buy | |
| Sigma-Aldrich | SAB2702144 | Monoclonal Anti-POLD1 antibody produced in mouse | 100μL | $476 | 2023-06-20 | Buy | |
| Sigma-Aldrich | WH0000891M1 | Monoclonal Anti-CCNB1 antibody produced in mouse clone 1C8, purified immunoglobulin, buffered aqueous solution | 100μg | $503 | 2023-01-07 | Buy | |
| Usbiological | 354576 | CCNB | 48Tests | $588 | 2021-12-16 | Buy | |
| Usbiological | 135970 | CDC2 | 50ul | $664 | 2021-12-16 | Buy |
G2/mitotic-specific cyclin-B1 Chemical Properties,Uses,Production
General Description
The cyclin B1 (CCNB1) gene is mapped to human chromosome 5q13.2. The gene codes for a 62kDa protein containing a classical cyclin box domain. CCNB1 shuttles between the nucleus and cytoplasm until prophase begins. It is a member of the cyclin family and is expressed at low levels in normal cells. CDK1 (cyclin-dependent kinase 1) belongs to the Ser/Thr protein kinase family. The gene encoding it is localized on human chromosome 10q21.
Biochem/physiol Actions
The cyclin B1 (CCNB1) and cyclin-dependent kinase 1 (CDK1) complex plays a crucial role in the regulation of mitosis. Elevated expression of CCNB1 has been observed in various types of human cancers including breast, lung, colon, prostate and head and neck cancers. Thus, this protein can be considered as a potent target for cancer vaccines.In addition, CCNB1 also serves as a prognostic biomarker for estrogen-receptor-positive (ER+) breast cancer. CDK1 (cyclin-dependent kinase 1) controls various mitotic processes like reorganization of the cytoskeleton and segregation of chromosomes. It is essential for the multiplication of mammalian cells.
G2/mitotic-specific cyclin-B1 Preparation Products And Raw materials
Raw materials
Preparation Products
G2/mitotic-specific cyclin-B1 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10362 | 58 |
| Supplier | Advantage |
|---|---|
| Wuhan Chemstan Biotechnology Co., Ltd. | 58 |