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1-(2-Amino-5-hydroxyphenyl)propan-1-one

CAS No.
35364-15-9
Chemical Name:
1-(2-Amino-5-hydroxyphenyl)propan-1-one
Synonyms
aminoketone;2-Amino-5-Hydroxy propiophenone;2'-amino-5'-hydroxypropiophenone;1-(2-Amino-5-hydroxyphenyl)-1-propanone;1-propanone,1-(2-amino-5-hydroxyhenyl)-;1-(2-Amino-5-hydroxyphenyl)propan-1-one;1-Propanone, 1-(2-amino-5-hydroxyphenyl)-
CBNumber:
CB93070610
Molecular Formula:
C9H11NO2
Molecular Weight:
165.19
MDL Number:
MFCD16877176
MOL File:
35364-15-9.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06

1-(2-Amino-5-hydroxyphenyl)propan-1-one Properties

Melting point 144.5-144.9 °C
Boiling point 363.9±32.0 °C(Predicted)
Density 1.195±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form Solid
pka 9.35±0.18(Predicted)
color Light Yellow to Brown
Stability Hygroscopic

1-(2-Amino-5-hydroxyphenyl)propan-1-one price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC A611480 1-(2-Amino-5-hydroxyphenyl)propan-1-one 35364-15-9 2.5g $1295 2021-12-16 Buy
American Custom Chemicals Corporation CHM0291115 2-AMINO-5-HYDROXYPROPIOPHENONE 95.00% 35364-15-9 5G $1443.75 2021-12-16 Buy
Matrix Scientific 178544 1-(2-Amino-5-hydroxyphenyl)propan-1-one 35364-15-9 1g $1486 2021-12-16 Buy
AK Scientific 5920CS 1-(2-Amino-5-hydroxyphenyl)propan-1-one 35364-15-9 25mg $252 2021-12-16 Buy
AK Scientific 5920CS 1-(2-Amino-5-hydroxyphenyl)propan-1-one 35364-15-9 250mg $455 2021-12-16 Buy
Product number Packaging Price Buy
A611480 2.5g $1295 Buy
CHM0291115 5G $1443.75 Buy
178544 1g $1486 Buy
5920CS 25mg $252 Buy
5920CS 250mg $455 Buy

1-(2-Amino-5-hydroxyphenyl)propan-1-one Chemical Properties,Uses,Production

Uses

1-(2-Amino-5-hydroxyphenyl)propan-1-one is a useful synthetic intermediate. It is used in the asymmetrical synthesis of (S)-4-ethyl-6,7,8,10- tetrahydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione, a key intermediate for synthesis of irinotecan and other camptothecin analogs. It is also used in the synthesis of E-?ring-?modified (RS)?-?camptothecin analogs as antitumor agents.

Preparation

Obtained by UV-irradiation of 3-ethyl-2,1-benzisoxazole in 66% sulfuric acid for 90 min at 80–90°
Also prepared from 2-nitro-5-hydroxybenzaldehyde (five steps) or from p-anisidine.

1-(2-Amino-5-hydroxyphenyl)propan-1-one Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 57)Suppliers
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Shanghai Likang New Materials Co., Limited
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1-(2-Amino-5-hydroxyphenyl)propan-1-one 1-propanone,1-(2-amino-5-hydroxyhenyl)- 2-Amino-5-Hydroxy propiophenone 1-Propanone, 1-(2-amino-5-hydroxyphenyl)- aminoketone 1-(2-Amino-5-hydroxyphenyl)-1-propanone 2'-amino-5'-hydroxypropiophenone 35364-15-9