2-[[(4-Anilinophenyl)imino]methyl]-4,6-dichlorophenol
- CAS No.
- 303215-67-0
- Chemical Name:
- 2-[[(4-Anilinophenyl)imino]methyl]-4,6-dichlorophenol
- Synonyms
- MitoBlock 6;2-[[(4-Anilinophenyl)imino]methyl]-4,6-dichlorophenol;2,4-Dichloro-6-[[[4-(phenylamino)phenyl]imino]methyl]phenol;Phenol, 2,4-dichloro-6-[[[4-(phenylamino)phenyl]imino]methyl]-;2,4-dichloro-6-[(E)-{[4-(phenylamino)phenyl]imino}methyl]phenol
- CBNumber:
- CB93139100
- Molecular Formula:
- C19H14Cl2N2O
- Molecular Weight:
- 357.23
- MDL Number:
- MFCD00557142
- MOL File:
- 303215-67-0.mol
Boiling point | 535.1±50.0 °C(Predicted) |
---|---|
Density | 1.28±0.1 g/cm3(Predicted) |
storage temp. | -20°C (des.) |
solubility | Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 6 mg/ml with warming). |
form | solid |
pka | 6.28±0.48(Predicted) |
color | Orange |
Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month. |
2-[[(4-Anilinophenyl)imino]methyl]-4,6-dichlorophenol price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Biosynth Carbosynth | FA71703 | 2-[[(4-Anilinophenyl)imino]methyl]-4,6-dichlorophenol | 303215-67-0 | 100mg | $50 | 2021-12-16 | Buy |
Biosynth Carbosynth | FA71703 | 2-[[(4-Anilinophenyl)imino]methyl]-4,6-dichlorophenol | 303215-67-0 | 250mg | $100 | 2021-12-16 | Buy |
Biosynth Carbosynth | FA71703 | 2-[[(4-Anilinophenyl)imino]methyl]-4,6-dichlorophenol | 303215-67-0 | 500mg | $150 | 2021-12-16 | Buy |
Biosynth Carbosynth | FA71703 | 2-[[(4-Anilinophenyl)imino]methyl]-4,6-dichlorophenol | 303215-67-0 | 1g | $275 | 2021-12-16 | Buy |
Biosynth Carbosynth | FA71703 | 2-[[(4-Anilinophenyl)imino]methyl]-4,6-dichlorophenol | 303215-67-0 | 2g | $500 | 2021-12-16 | Buy |
2-[[(4-Anilinophenyl)imino]methyl]-4,6-dichlorophenol Chemical Properties,Uses,Production
Description
MitoBloCK-6 (303215-67-0) inhibits redox-regulated protein translocation into mitochondria. It attenuates the import of Erv1 substrates by inhibition of Erv1 oxidase activity (the import of Tim23 and AAC was decreased by ~50% at 20 μM). MitoBloCK-6 elucidated an unexpected role for Erv1 in the carrier import pathway, namely transferring substrates from the translocase of the outer membrane complex into the small Tim complexes. It impaired cardiac development in zebrafish embryos and induced apoptosis via the release of cytochrome c in human embryonic stem cells but not differentiated cells.1
Uses
MitoBlock-6 is mitochondrial import inhibitor. It inhibits redox-regulated protein translocation into the mitochondria.
References
1) Dabir?et al. (2013),?A small molecule inhibitor of redox-regulated protein translocation into mitochondria; Dev. Cell,25?81
2-[[(4-Anilinophenyl)imino]methyl]-4,6-dichlorophenol Preparation Products And Raw materials
Raw materials
Preparation Products
2-[[(4-Anilinophenyl)imino]methyl]-4,6-dichlorophenol Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696,15000506266 15000506266 | China | 4296 | 55 | |
Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 3769 | 55 |
Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | info@SuperLan-chem.com | China | 9941 | 58 |
DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9412 | 58 |
Changzhou Chenhong Biotechnology Co., Ltd. | 0519-85788828 13775037613 | sales@chemrenpharm.com | China | 3600 | 58 |
InvivoChem | 13549236410 | sales@invivochem.cn | China | 6755 | 58 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 23963 | 58 |
Wuhan Acumen Bio-Technology Co.,ltd | 027-027-16602739303 16602739303 | 673003916@qq.com | China | 2518 | 58 |
RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9268 | 58 |