Piromelatine
- CAS No.
- 946846-83-9
- Chemical Name:
- Piromelatine
- Synonyms
- NEU-P11;NEU-P-11;NEU-P 11;Piromelatine;Piromelatine (Neu-P11);Piromelatine 946846-83-9;N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-4-oxopyran-2-carboxamide;4H-Pyran-2-carboxamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-4-oxo-
- CBNumber:
- CB93151928
- Molecular Formula:
- C17H16N2O4
- Molecular Weight:
- 312.32
- MDL Number:
- MFCD30146157
- MOL File:
- 946846-83-9.mol
| form | Solid |
|---|---|
| color | Light yellow to yellow |
| FDA UNII | S3UN2146K9 |
Piromelatine price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0025619 | Piromelatine 99.21% | 946846-83-9 | 5mg | $200 | 2021-12-16 | Buy |
| ChemScene | CS-0025619 | Piromelatine 99.21% | 946846-83-9 | 10mg | $300 | 2021-12-16 | Buy |
| ChemScene | CS-0025619 | Piromelatine 99.21% | 946846-83-9 | 50mg | $850 | 2021-12-16 | Buy |
| ChemScene | CS-0025619 | Piromelatine 99.21% | 946846-83-9 | 100mg | $1250 | 2021-12-16 | Buy |
Piromelatine Chemical Properties,Uses,Production
Description
Piromelatine is a novel investigational agent that has agonist activity at MT1 and MT2 along with agonism at 5-HT1A/1D receptors. A phase II randomized clinical trial (N 1/4 120) in primary insomnia resulted in significant improvement in insomnia symptoms.
Clinical claims and research
Piromelatine known as Neu-P11 is a newer melatonin receptor agonist underdevelopmental stage. It acts on MT1, MT2, and also 5-HT1A/5- HT1D receptors. It has demonstrated improvement in the sleep cycle of primary insomnia patients and reducing sleep disturbances in Phase II clinical trial. It was found to have efficacy in maintaining deeper sleep, less arousal, and also preserving REM sleep pattern. In the clinical trial, piromelatine was well tolerated with no adverse effects on psychomotor performance the following day (She et al., 2014).
Piromelatine Preparation Products And Raw materials
Raw materials
Preparation Products
Piromelatine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2923 | 55 | |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 3717 | 55 |
| Shanghai Rechem science Co., Ltd. | 21-31433387 15618786686 | sales@rechemscience.com | China | 2987 | 58 |
| Shanghai Biopharmaleader Co., Ltd. | +86 18721201413 | sales@biopharmaleader.com | China | 1720 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Jinan Jiuli Biotechnology Co. , Ltd. | 14768611851 | 486064515@qq.com | China | 2083 | 58 |
| Kaifeng Mingren Pharmaceutical Co.,LTD | 0371-65741762 | sales@hasunny.com | China | 2380 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24017 | 58 |
| Henan Alpha Chemical Co., Ltd. | 0371-55013243 15324716602 | 2853979810@qq.com | China | 10010 | 58 |