Aminooxy-PEG2-azide
- CAS No.
- 1043426-13-6
- Chemical Name:
- Aminooxy-PEG2-azide
- Synonyms
- Aminooxy-PEG2-azide;O-(2-(2-(2-Azidoethoxy)ethoxy)ethyl)hydroxylamine
- CBNumber:
- CB93162832
- Molecular Formula:
- C6H14N4O3
- Molecular Weight:
- 190.2
- MDL Number:
- MFCD24458259
- MOL File:
- 1043426-13-6.mol
Aminooxy-PEG2-azide Chemical Properties,Uses,Production
Description
Aminooxy-PEG2-azide contain an azide and an aminooxy group. The aminooxy group reacts with an aldehyde or ketone group to form a oxime linkage. The azide group enables Click Chemistry. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term. Immediate use (within 1 week) is highly recommended.
Biological Activity
Aminooxy-PEG2-azide is a PROTAC linker belonging to the PEG class, which can be used to synthesize PROTAC molecules.It is also a non-cleavable ADC linker containing 2-unit PEG, which can be used to synthesize antibody drug conjugates (ADCs).
in vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
target
| PEGs
| Non-cleavable
|
Aminooxy-PEG2-azide Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32165 | 58 |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3148 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38632 | 58 | |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2995 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52924 | 58 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7887 | 56 |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-0431-80514535 19917294565 | et@chemextension.com | China | 3982 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9806 | 58 |
View Lastest Price from Aminooxy-PEG2-azide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-24 | Aminooxy-PEG2-azide
1043426-13-6
|
US $49.00-115.00 / mg | 10g | TargetMol Chemicals Inc. | |||
 |
2024-04-02 | Aminooxy-PEG2-azide
1043426-13-6
|
US $0.00 / mg | 500mg | >98.00% | 500mg | Xian confluore Biological Technology Co., Ltd. |
-
- Aminooxy-PEG2-azide
1043426-13-6
- US $49.00-115.00 / mg
- TargetMol Chemicals Inc.
-
- Aminooxy-PEG2-azide
1043426-13-6
- US $0.00 / mg
- >98.00%
- Xian confluore Biological Technology Co., Ltd.