ChemicalBook >> CAS DataBase List >>2'-O-Methylcytidine
2'-O-Methylcytidine
- CAS No.
- 2140-72-9
- Chemical Name:
- 2'-O-Methylcytidine
- Synonyms
- 4-amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one;OMe-rC;2'-OMe-C;2'-OMe-C;2'-OMe-rC;2'-OMe-Cr;2'-O-Me-dC;2'-O-Me-rC;2'-OMe Cytidine;2'-OMe-cytidine
- CBNumber:
- CB9324099
- Molecular Formula:
- C10H15N3O5
- Molecular Weight:
- 257.24
- MDL Number:
- MFCD11519076
- MOL File:
- 2140-72-9.mol
- MSDS File:
- SDS
Last updated:2024-08-28 13:53:27
Melting point | 252-253 C |
---|---|
Boiling point | 506.0±60.0 °C(Predicted) |
Density | 1.68±0.1 g/cm3(Predicted) |
storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
solubility | Soluble in DMSO. |
pka | 13.37±0.70(Predicted) |
form | Powder |
color | White to Off-white |
PH | 4.2 |
λmax | 281 (pH 1);273 (EtOH) |
InChI | InChI=1S/C10H15N3O5/c1-17-8-7(15)5(4-14)18-9(8)13-3-2-6(11)12-10(13)16/h2-3,5,7-9,14-15H,4H2,1H3,(H2,11,12,16)/t5-,7-,8-,9-/m1/s1 |
InChIKey | RFCQJGFZUQFYRF-ZOQUXTDFSA-N |
SMILES | OC[C@H]1O[C@@H](N2C=CC(N)=NC2=O)[C@H](OC)[C@@H]1O |
CAS DataBase Reference | 2140-72-9(CAS DataBase Reference) |
FDA UNII | 5XD9IH2G27 |
SAFETY
Risk and Safety Statements
Hazard Codes | Xi |
---|---|
Risk Statements | 36/37/38 |
Safety Statements | 26-36-24/25 |
WGK Germany | 3 |
HS Code | 29349990 |
2'-O-Methylcytidine price More Price(21)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TCI Chemical | M2317 | 2'-O-Methylcytidine >98.0%(HPLC)(T) | 2140-72-9 | 200mg | $47 | 2024-03-01 | Buy |
TCI Chemical | M2317 | 2'-O-Methylcytidine >98.0%(HPLC)(T) | 2140-72-9 | 1g | $185 | 2024-03-01 | Buy |
Alfa Aesar | J65528 | 2'-O-Methylcytidine, 99% | 2140-72-9 | 1g | $64.65 | 2024-03-01 | Buy |
Usbiological | 296261 | 2'-O-Methylcytidine | 2140-72-9 | 300mg | $333 | 2021-12-16 | Buy |
TRC | M294660 | 2’-O-MethylCytidine | 2140-72-9 | 5g | $480 | 2021-12-16 | Buy |
2'-O-Methylcytidine Chemical Properties,Uses,Production
Description
2'-O-Methylcytidine is a nucleoside with a hydroxyl group on the 2' carbon, making it an effective viral replication inhibitor. 2'-O-Methylcytidine is also metabolized by nucleotide salvage pathways and may be able to bind to the response element on DNA, which could inhibit protein synthesis in cancer cells. It is an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50 = 3.8 μM). It inhibits HCV replication in a replicon assay (IC50 = 21.2 μM).
Chemical Properties
White powder
Uses
Cytidine analog.
Uses
2'-O-Methylcytidine is used in the preparation of nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase.
Definition
ChEBI: 2'-O-methylcytidine is a methylcytidine.
2'-O-Methylcytidine Preparation Products And Raw materials
Global( 253)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Yunbio Tech Co.,Ltd. | +86-010-60605551 +86-18046518538 | yunbiochem@126.com | China | 321 | 58 |
LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20274 | 58 |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29793 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29880 | 58 |
Nanjing Baifuli Technology Co., Ltd. | +86-15335185688 | sales@unisyn.cn | CHINA | 332 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
View Lastest Price from 2'-O-Methylcytidine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-08-07 | 2'-O-Methylcytidine
2140-72-9
|
US $0.00 / KG | 1KG | 98% | 300KG per month | Yunbio Tech Co.,Ltd. | ||
2024-03-29 | 2'-O-Methylcytidine
2140-72-9
|
US $6.00-1.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | ||
2023-04-04 | 2'-O-Methylcytidine
2140-72-9
|
US $0.00-0.00 / kg | 1kg | 98% | 500kg per month | Zhejiang Hengkang Pharmaceutical Co., Ltd. |
- 2'-O-Methylcytidine
2140-72-9
- US $0.00 / KG
- 98%
- Yunbio Tech Co.,Ltd.
- 2'-O-Methylcytidine
2140-72-9
- US $6.00-1.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
- 2'-O-Methylcytidine
2140-72-9
- US $0.00-0.00 / kg
- 98%
- Zhejiang Hengkang Pharmaceutical Co., Ltd.
2140-72-9(2'-O-Methylcytidine)Related Search:
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(R)-(-)-TETRAHYDROFURFURYL ALCOHOL
1of4
2'-OMe-C
4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-3-methoxy-5-methylol-tetrahydrofuran-2-yl]pyrimidin-2-one
4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]pyrimidin-2-one
4-azanyl-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxy-oxolan-2-yl]pyrimidin-2-one
2'-OMe Cytidine
4-aMino-1-[(2R,3R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)-3-Methoxyoxolan-2-yl]-1,2-dihydropyriMidin-2-one
2'-O-Methylcytidine, >=99%
2'-O-METHYLCYTIDINE
2''-(O-METHYL)-CYTIDINE, HPLC PURIFIED, 98% PURE WITH HPLC UV CHROMATOGRAM
2'-O-Methylcytidineanhydrous
2'-O-Methyl-D-cytidine
2'-O-Methylcytidine, >98.0%(HPLC)
2'-O-Methylcytidine>
2'-OMe-rC
2'-O-Methylcytidine USP/EP/BP
4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-1,2-dihydropyrimidin-2-one
2'-OMe-Cr
2’-O-Methyl cytidine, RNA nucleoside Cm
4-amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one
OMe-rC
2'-O-Methylcytidine
2'-OMe-cytidine
2'-O-Me-dC
2'-O-Me-rC
Cytidine, 2'-O-methyl-
2'-OMe-C
2140-72-9
Nucleosides, Nucleotides, Oligonucleotides
Nucleoside Analogs
BioChemical
Biochemicals and Reagents
Bases & Related Reagents
Carbohydrates & Derivatives
Heterocycles
Nucleotides
Nucleosides, Nucleotides, Oligonucleotides
Biochemicals and Reagents
Nucleoside Analogs
Nucleosides
Modified(deoxy)nucleoside
Nucleosides-2'-OMe Nucleosides