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Clinofibrate

CAS No.
30299-08-2
Chemical Name:
Clinofibrate
Synonyms
S 8527;lipoclin;bis(oxy);CLINOFIBRATE;Clinofibrate >CLINOFIBRATE (S-8527);Clinofibrate USP/EP/BP;2,2'-(cyclohexyliden...;CLINOFIBRATE(FORR&DONLY);bis(2-methylbutanoic acid)
CBNumber:
CB9333525
Molecular Formula:
C28H36O6
Molecular Weight:
468.58
MDL Number:
MFCD00865769
MOL File:
30299-08-2.mol
Last updated:2024-11-19 20:33:22

Clinofibrate Properties

Melting point 143-145°C
Boiling point 498.6°C (rough estimate)
Density 1.1005 (rough estimate)
refractive index 1.4482 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Methanol (Sligthly)
form Solid
pka 3.00±0.10(Predicted)
color White to Off-White
Merck 14,2357
CAS DataBase Reference 30299-08-2(CAS DataBase Reference)
FDA UNII 0374EZJ8CU

SAFETY

Risk and Safety Statements

RTECS  ES8900000
HS Code  2918.99.4700

Clinofibrate price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical C3100 Clinofibrate >98.0%(HPLC) 30299-08-2 200mg $93 2024-03-01 Buy
TCI Chemical C3100 Clinofibrate >98.0%(HPLC) 30299-08-2 1g $282 2024-03-01 Buy
TRC C580100 Clinofibrate 30299-08-2 5mg $50 2021-12-16 Buy
TRC C580100 Clinofibrate 30299-08-2 100mg $590 2021-12-16 Buy
Biosynth Carbosynth FC20487 Clinofibrate 30299-08-2 50mg $841.5 2021-12-16 Buy
Product number Packaging Price Buy
C3100 200mg $93 Buy
C3100 1g $282 Buy
C580100 5mg $50 Buy
C580100 100mg $590 Buy
FC20487 50mg $841.5 Buy

Clinofibrate Chemical Properties,Uses,Production

Chemical Properties

White Solid

Originator

Lipocrin,Sumitomo,Japan,1981

Uses

Clinofibrate is an antilipemic, used as an anti-atherosclerosis agent.

Definition

ChEBI: Clinofibrate is an organic molecular entity.

Manufacturing Process

Into a mixture of 6.0 g of a bishydroxyphenyl derivative, and 44.0 g of methyl ethyl ketone was added 16.2 g of crushed potassium hydroxide or sodium hydroxide. Chloroform was added dropwise into the above mixture with stirring at 20°C to 80°C, and the resultant mixture was heated for 20 hours under reflux to complete the reaction. Thereafter the reaction mixture was concentrated to give a residue. Into the residue was added water. After cooling, the resultant mixture was treated with activated charcoal and acidified by diluted hydrochloric acid or sulfuric acid to give an oily substance. The oily substance was extracted by ether and the ether solution was contacted with aqueous diluted Na2CO3 solution. The separated aqueous layer was washed with ether, acidified and again extracted with ether. The obtained ester layer was dried over anhydrous sodium sulfate and concentrated to give 1.0 g of a crude product which was purified by recrystallization or chromatography, to give crystals MP 143°C to 146°C (decomp.)

Therapeutic Function

Antihyperlipoproteinemic

Clinofibrate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 157)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29882 58
Xiamen AmoyChem Co., Ltd
+86-86-5926051114 +8618959220845 sales@amoychem.com China 6383 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49374 58
SIMAGCHEM CORP
+86-13806087780 sale@simagchem.com China 17365 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32165 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34553 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-89586680 +86-18192503167 1026@dideu.com China 7724 58
AFINE CHEMICALS LIMITED
+86-0571-85134551 sales@afinechem.com China 15354 58
Dayang Chem (Hangzhou) Co.,Ltd.
571-88938639 +8617705817739 info@dycnchem.com China 52849 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58

View Lastest Price from Clinofibrate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Clinofibrate pictures 2024-11-19 Clinofibrate
30299-08-2
US $39.00-113.00 / mg 99.84% 10g TargetMol Chemicals Inc.
Clinofibrate pictures 2020-05-12 Clinofibrate
30299-08-2
US $0.00-0.00 / KG 1KG 99.0% 500 MT Shaanxi Dideu Medichem Co. Ltd
Clinofibrate pictures 2019-09-02 Clinofibrate
30299-08-2
US $7.00 / KG 1KG 99% 1000KG Career Henan Chemical Co
  • Clinofibrate pictures
  • Clinofibrate
    30299-08-2
  • US $39.00-113.00 / mg
  • 99.84%
  • TargetMol Chemicals Inc.
  • Clinofibrate pictures
  • Clinofibrate
    30299-08-2
  • US $0.00-0.00 / KG
  • 99.0%
  • Shaanxi Dideu Medichem Co. Ltd
  • Clinofibrate pictures
  • Clinofibrate
    30299-08-2
  • US $7.00 / KG
  • 99%
  • Career Henan Chemical Co

Clinofibrate Spectrum

2,2’-cyclohexane-1,1-diylbis(p-phenyleneoxy)bis(2-methylbutyricacid) lipoclin 2,2'-(cyclohexylidenebis(4,1-phenyleneoxy))bis(2-methyl)-butanoic acid CLINOFIBRATE CLINOFIBRATE(FORR&DONLY) 1,1-Bis[4'-(1''-carboxy-1''-methylpropoxy)phenyl]cyclohexane Butanoic acid, 2,2'-[cyclohexylidenebis(4,1-phenyleneoxy)]bis[2-methyl- S 8527 2,2'-[(1,1-Cyclohexanediyl)bis(4,1-phenyleneoxy)]bis(2-methylbutanoic acid) 2,2'-[Cyclohexylidenebis(4,1-phenyleneoxy)]bis(2-methylbutyric acid) 2,2'-(cyclohexyliden... 2,2,-((cyclohexane-1,1-diylbis(4,1-phenylene))bis(oxy))bis(2-methylbutanoic acid) 2,2'-((Cyclohexane-1,1-diylbis(4,1-phenylene) bis(2-methylbutanoic acid) bis(oxy) 2,2’-(4,4’-cyclohexylidenediphenoxy)-2,2’-dimethyldibutyricacid 2,2’-cyclohexane-1,1-diylbis(p-phenyleneoxy)bis-(2-methyl-butyricaci CLINOFIBRATE (S-8527) Clinofibrate > 2,2'-(4,4'-Cyclohexylidenediphenoxy)-2,2'-dimethyldibutanoic Acid Clinofibrate USP/EP/BP Clinofibrate (10mM in DMSO) 2,2’-[[Cyclohexane-1,1-diylbis(4,1-phenylene)]bis(oxy)]bis(2-methylbutanoic Acid) 30299-08-2 30298-08-2 C28H36O6 API Inhibitors Aromatics Intermediates & Fine Chemicals Pharmaceuticals