Cysteamine hydrochloride
- CAS No.
- 156-57-0
- Chemical Name:
- Cysteamine hydrochloride
- Synonyms
- CYSTEAMINE HCL;2-AMINOETHANETHIOL HYDROCHLORIDE;2-MERCAPTOETHYLAMINE HYDROCHLORIDE;Mercaptamine hydrochloride;mercaptoethylammonium chloride;2-Mercaptoethylammonium chloride;2-AMINOETHANE-1-THIOL HYDROCHLORIDE;2-AMINOETHANETHIOL HCL;Aminoethanethiol hydrochloride;DECARBOXYCYSTEINE HYDROCHLORIDE
- CBNumber:
- CB9337215
- Molecular Formula:
- C2H8ClNS
- Molecular Weight:
- 113.61
- MDL Number:
- MFCD00012904
- MOL File:
- 156-57-0.mol
- MSDS File:
- SDS
| Melting point | 67-71 °C |
|---|---|
| Boiling point | 238.5℃[at 101 325 Pa] |
| Density | 0.75 |
| vapor pressure | 5.333Pa at 25℃ |
| refractive index | 1.6100 (estimate) |
| storage temp. | 2-8°C |
| solubility | H2O: 1 m at 20 °C, clear, colorless |
| form | Crystalline Powder or Pellets |
| color | White |
| PH | 3.3-5.0 (400g/l, H2O, 20℃) |
| biological source | synthetic (organic) |
| Water Solubility | VERY SOLUBLE |
| Sensitive | Hygroscopic |
| λmax | λ: 280 nm Amax: ≤0.3 |
| Merck | 14,2779 |
| BRN | 3590083 |
| Stability | Stable, but hygroscopic. Incompatible with strong oxidizing agents. |
| InChIKey | OGMADIBCHLQMIP-UHFFFAOYSA-N |
| LogP | -2.14 at 25℃ |
| CAS DataBase Reference | 156-57-0(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | IF1B771SVB |
| EPA Substance Registry System | Cysteamine hydrochloride (156-57-0) |
| Absorption | cut-off at 270nm in H2O at 1M |
| UNSPSC Code | 85151701 |
| NACRES | NA.51 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H317-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 36/37/39-26-36 | |||||||||
| RIDADR | UN 3335 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | KJ0200000 | |||||||||
| F | 1-3-10-13 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29309070 | |||||||||
| Toxicity | LD50 orally in Rabbit: 642 mg/kg | |||||||||
| NFPA 704 |
|
Cysteamine hydrochloride price More Price(55)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.02835 | Cysteaminium chloride for synthesis | 156-57-0 | 10g | $44.5 | 2024-03-01 | Buy |
| Sigma-Aldrich | 8.02835 | Cysteaminium chloride for synthesis | 156-57-0 | 25g | $55.1 | 2024-03-01 | Buy |
| Sigma-Aldrich | 8.02835 | Cysteaminium chloride for synthesis | 156-57-0 | 100g | $148 | 2024-03-01 | Buy |
| Sigma-Aldrich | 30078 | Cysteamine hydrochloride BioXtra | 156-57-0 | 25g | $139 | 2024-03-01 | Buy |
| TCI Chemical | A0296 | 2-Aminoethanethiol Hydrochloride >95.0%(T) | 156-57-0 | 25g | $40 | 2024-03-01 | Buy |
Cysteamine hydrochloride Chemical Properties,Uses,Production
Description
Cysteamine is a stable aminothiol with radioprotective activities. It reduces ionizing radiation-induced death and chromosomal damage in mice in a dose-dependent manner. Cysteamine binds rapidly and temporarily to plasma proteins upon administration and this activity is directly correlated to its radioprotective effects. In vitro, 0.1 mM cysteamine depletes 90% of free cystine from cystinotic fibroblasts. Formulations containing cysteamine have been used to treat nephropathic cystinosis and reduce glomerular deterioration in humans.
Chemical Properties
White Solid
Uses
Cysteamine hydrochloride has been used in the in-situ generation of chiral cysteamine-capped cadmium sulfide quantum dots (CA-CdS QDs) for the sensing of Cd2+ and S2-.
Uses
An inhibitor of DMBA-induced mammary tumors2-Mercaptoethylamine hydrochloride acts as a precursor in taurine biosynthesis and component of coenzyme A. It is involved in the preparation of active pharmaceutical ingredients like ranitidine and nizatidine. It acts as an antidote for acetaminophen poisoning. Further, it is used in the oral treatment of nephropathic cystinosis, radiation sickness and disorders of cysteine excretion. In addition to this, it serves as an antioxidant and an inhibitor of 7,12-Dimethylbenz[a]anthracene (DMBA)-induced tumors.
Uses
Cysteamine hydrochloride is used as an antioxidant and in radiation therapy.
General Description
Cysteamine is an aminothiol that can reduce important oxidized disulfide molecules such as cystine to yield cysteine.
Hazard
Toxic by inhalation and ingestion.
Biochem/physiol Actions
Cysteamine is an aminothiol that can reduce important oxidized disulfide molecules such as cystine to yield cysteine. Cysteamine is used in a wide range of applications from regulation of gene expression, to depletion of somatostatin, to coating of nanoparticles.
Synthesis
In particular to synthesizing cysteamine hydrochloride in alkali surroundings, which is characterized in that ethanolamine solution and sulfate solution are used as raw material; 2- amino ethyl sulfate is firstly synthesized before made into ring in alkaline solution by 2-amino ethyl sulfate and carbon disulfide, thereby getting Alpha -mercaptothiazoline; alkaline hydrolysis is made upon Alpha -mercaptothiazoline to produce cysteamine hydrochloride.
Purification Methods
Purify the salt by recrystallisation from EtOH. It is freely soluble in H2O and should be stored in a dry atmosphere. [Mills & Bogert J Am Chem Soc 62 1177 1940.] The picrate has m 125-126o; see previous entry for free base. [Beilstein 4 IV 1570.]
Cysteamine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
1of3
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2986 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| Shandong Huisheng Import & Export Co., Ltd. | +86-13176845580 +86-13176845580 | da@zhongda-biotech.com | China | 232 | 58 |
| Anhui Zhongda Biotechnology Co., Ltd | +8615689548120 | linda@zhongda-biotech.com | China | 193 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8803 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5881 | 58 |
| Hebei Dangtong Import and export Co LTD | +86-86-4001020630 +8619831957301 | admin@hbdangtong.com | China | 1000 | 58 |
| Anhui Zhongda Biotechnology Co., Ltd | +8619956560829 | justine@zhongda-biotech.com | China | 286 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 973 | 58 |
| Hangzhou Hyper Chemicals Limited | +86-0086-57187702781 +8613675893055 | info@hyper-chem.com | China | 295 | 58 |
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- Cysteamine Hydrochloride: An Overview of Properties, Composition, Applications, and Safe Storage Practices
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- Nov 28，2024
View Lastest Price from Cysteamine hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-02-26 | Sodium Glycinate
6000-44-8
|
US $120.00 / kg | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co.,Ltd | |
 |
2025-02-26 | Cysteamine hcl
156-57-0
|
US $180.00 / kg | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co.,Ltd | |
 |
2025-02-26 | Cysteamine hydrochloride
156-57-0
|
US $0.00-0.00 / kg/drum kg/bag | 25kg/drum kg/bag | 75% 95% 99% | 1000000MT | Yancheng Green Chemicals Co.,Ltd |
-
- Sodium Glycinate
6000-44-8
- US $120.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd
-
- Cysteamine hcl
156-57-0
- US $180.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd
-
- Cysteamine hydrochloride
156-57-0
- US $0.00-0.00 / kg/drum kg/bag
- 75% 95% 99%
- Yancheng Green Chemicals Co.,Ltd