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METHYL 3-METHOXY-4-METHYLBENZOATE

CAS No.
3556-83-0
Chemical Name:
METHYL 3-METHOXY-4-METHYLBENZOATE
Synonyms
METHYL 4-METHYL-M-ANISATE;METHYL 3-METHOXY-P-TOLUATE;METHYL 3-METHOXY-4-METHYLBENZOATE;4-METHYL-M-ANISIC ACID METHYL ESTER;Methyl3-Methoxy-4-methylbenzoate>3-METHOXY-P-TOLUIC ACID METHYL ESTER;Methyl 4-methyl-3-(methyloxy)benzoate;Methyl 3-methoxy-4-methylbenzoate, 98+%;3-Methoxy-4-methylbenzoate methyl ester;3-Methoxy-4-methyl-benzoesuremethylester
CBNumber:
CB9372636
Molecular Formula:
C10H12O3
Molecular Weight:
180.2
MDL Number:
MFCD00082710
MOL File:
3556-83-0.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06

METHYL 3-METHOXY-4-METHYLBENZOATE Properties

Melting point 50-54 °C (lit.)
Boiling point 119-120°C 1mm
Density 1.075±0.06 g/cm3(Predicted)
refractive index 1.5295
Flash point >230 °F
form powder to crystal
color White to Almost white
BRN 1948339
CAS DataBase Reference 3556-83-0(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  1
HS Code  29189900
NFPA 704
1
0 0

METHYL 3-METHOXY-4-METHYLBENZOATE price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 528781 Methyl 3-methoxy-4-methylbenzoate 96% 3556-83-0 25g $885 2023-06-20 Buy
TCI Chemical M1427 Methyl 3-Methoxy-4-methylbenzoate >98.0%(GC) 3556-83-0 5g $40 2024-03-01 Buy
TCI Chemical M1427 Methyl 3-Methoxy-4-methylbenzoate >98.0%(GC) 3556-83-0 25g $132 2024-03-01 Buy
Alfa Aesar B22695 Methyl 3-methoxy-4-methylbenzoate, 98% 3556-83-0 5g $100.65 2024-03-01 Buy
Alfa Aesar B22695 Methyl 3-methoxy-4-methylbenzoate, 98% 3556-83-0 1g $39.5 2021-12-16 Buy
Product number Packaging Price Buy
528781 25g $885 Buy
M1427 5g $40 Buy
M1427 25g $132 Buy
B22695 5g $100.65 Buy
B22695 1g $39.5 Buy

METHYL 3-METHOXY-4-METHYLBENZOATE Chemical Properties,Uses,Production

Preparation

Methyl 3-methoxy-4-methylbenzoate is synthesized by the following steps:A mixture of methyl 3-hydroxy-4-methylbenzoate 36 (25 g, 0.151 mol),  Me2SO4 (28.3 ml, 0.386 mol), anhydrous K2CO3 (103.5 g, 0.75 mol) was  refluxed in acetone for 2 hours. K2CO3 was filtered off, washed  thoroughly with acetone. The filtrates were combined and concentrated,  the residue was redissolved in EtOAc washed with water, dried  (anhydrous Na2SO4), filtered and concentrated in vacuo to furnish a white solid (19.52 g).  Yield : 72%.

Chemical Properties

White low melting solid

Uses

Methyl 3-Methoxy-4-methylbenzoate has been used as a reactant in the preparation of an antimalaria drug that consists of the 4-aminoquinoline pharmacophore of chloroquine with clotrimazole-based antimalarials.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 33, p. 1771, 1990 DOI: 10.1021/jm00168a036

General Description

Methyl 3-methoxy-4-methylbenzoate can be prepared by reacting diazomethane with 3-methoxy-4-methylbenzoic acid in ether.

7151-68-0
75-36-5
3556-83-0
Synthesis of METHYL 3-METHOXY-4-METHYLBENZOATE from 3-Methoxy-4-methylbenzoic acid and Acetyl chloride
Global( 174)Suppliers
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Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29791 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 18747 58
Accela ChemBio Inc.
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Alchem Pharmtech,Inc.
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CONIER CHEM AND PHARMA LIMITED
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career henan chemical co
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Fuxin Pharmaceutical
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Hefei TNJ Chemical Industry Co.,Ltd.
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Win-Win chemical CO., Limited
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Dayang Chem (Hangzhou) Co.,Ltd.
571-88938639 +8617705817739 info@dycnchem.com China 52849 58

View Lastest Price from METHYL 3-METHOXY-4-METHYLBENZOATE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
	 Methyl 3-methoxy-4-methylbenzoate pictures 2020-01-10 Methyl 3-methoxy-4-methylbenzoate
3556-83-0
US $1.00 / KG 1g 98% 200kgs Career Henan Chemical Co

METHYL 3-METHOXY-4-METHYLBENZOATE Spectrum

METHYL 3-METHOXY-P-TOLUATE METHYL 3-METHOXY-4-METHYLBENZOATE 3-Methoxy-4-methyl-benzoesuremethylester 4-METHOXY-3-METHYLBENZOIC ACID METHYL ESTER Methyl 3-methoxy-4-methylbenzoate, 98+% Benzoic acid, 3-Methoxy-4-Methyl-, Methyl ester 3-Methoxy-4-methylbenzoic Acid Methyl Ester 3-Methoxy-p-toluic Acid Methyl Ester 4-Methyl-m-anisic Acid Methyl Ester Methyl 3-Methoxy-p-toluate Methyl 4-Methyl-m-anisate Methyl 4-methyl-3-(methyloxy)benzoate 4-METHYL-M-ANISIC ACID METHYL ESTER METHYL 4-METHYL-M-ANISATE 3-METHOXY-4-METHYLBENZOIC ACID METHYL ESTER 3-METHOXY-P-TOLUIC ACID METHYL ESTER Methyl3-Methoxy-4-methylbenzoate> 3-Methoxy-4-Methylbenzoic Acid Methyl Easter 3-Methoxy-4-methylbenzoate methyl ester 3556-83-0 CH3OC6H3CH3CO2CH3 Organic Building Blocks Esters Building Blocks Carbonyl Compounds C10 to C11 Carbonyl Compounds Esters Acids & Esters Anisoles, Alkyloxy Compounds & Phenylacetates Aromatic Esters C10 to C11