D(+)-Malic acid
- CAS No.
- 636-61-3
- Chemical Name:
- D(+)-Malic acid
- Synonyms
- D-MALIC ACID;(R)-MALIC ACID;D-(+)-MALIC ACID;(2R)-2-Hydroxybutanedioic acid;D-(+)-MaL;D(+)-Malic;D-APPLE ACID;(R)-malicaci;l(+)-malicaci;D-Aepfelsaeure
- CBNumber:
- CB9373789
- Molecular Formula:
- C4H6O5
- Molecular Weight:
- 134.09
- MDL Number:
- MFCD00004245
- MOL File:
- 636-61-3.mol
- MSDS File:
- SDS
Melting point | 98-102 °C (lit.) |
---|---|
Boiling point | 167.16°C (rough estimate) |
alpha | 2.2 º (c=3, H2O) |
Density | 1.60 |
refractive index | 6.5 ° (C=10, Acetone) |
storage temp. | Store below +30°C. |
solubility | Soluble in methanol, ethanol, acetone, ether. |
pka | 3.61±0.23(Predicted) |
form | Crystalline Powder |
color | White |
PH | 2.2 (10g/l, H2O, 20℃) |
optical activity | [α]20/D +28.0±2°, c = 5.5% in pyridine |
Water Solubility | soluble |
Merck | 14,5707 |
BRN | 1723540 |
LogP | -1.370 (est) |
CAS DataBase Reference | 636-61-3(CAS DataBase Reference) |
FDA UNII | P750Y95K96 |
NIST Chemistry Reference | (r)-Hydroxybutanedioic acid(636-61-3) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS05,GHS07 |
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Signal word | Danger | |||||||||
Hazard statements | H315-H318-H335 | |||||||||
Precautionary statements | P261-P280-P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 37/38-41-36/37/38 | |||||||||
Safety Statements | 26-36-37/39 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | ON7260000 | |||||||||
HS Code | 29181980 | |||||||||
NFPA 704 |
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D(+)-Malic acid price More Price(45)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 02300 | D-(+)-Malic acid unnatural form, ≥97.0% (T) | 636-61-3 | 1g | $34.02 | 2024-03-01 | Buy |
Sigma-Aldrich | 8.00763 | D-(+)-Malic acid for the resolution of racemates for synthesis | 636-61-3 | 5G | $120 | 2024-03-01 | Buy |
Sigma-Aldrich | 46940-U | D-Malic acid analytical standard | 636-61-3 | 1kit | $37 | 2024-03-01 | Buy |
Sigma-Aldrich | 02300 | D-(+)-Malic acid unnatural form, ≥97.0% (T) | 636-61-3 | 5g | $83.3 | 2024-03-01 | Buy |
TCI Chemical | M0021 | D-(+)-Malic Acid >98.0%(GC)(T) | 636-61-3 | 5g | $21 | 2024-03-01 | Buy |
D(+)-Malic acid Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powde
Uses
D-(+)-Malic acid can be used:
- As a starting material for the enantioselective total synthesis of (?)-erinapyrone B.
- As a chiral organocatalyst in the synthesis of α-aminophosphonates from various aldehydes, aniline, and diethyl phosphite.
Uses
The naturally occuring isomer is the L-form which has been found in apples and many other fruits and plants. Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid rece
Uses
D-(+)-Malic acid used as an acidulant and flavoring agent, food additive. And it is also used in the place of the less sour citric acid in sour sweets.
Definition
ChEBI: An optically active form of malic acid having (R)-configuration.
Biological Activity
D-(+)-Malic acid, an active isomer of Malic acid, is a competitive inhibitor of L(--)malic acid transport.
Synthesis
Malic acid is isolated from immature apples; industrially prepared is obtained by catalytic oxidation of benzene, then reacting with water at high temperature and high pressure to generate maleic anhydride.
in vitro
Some bacteria belonging to Arthrobacter, Brevibacterium, Corynebacterium, Pseudomonas, Bacillus, and Acinetobacter produced D-(+)-Malic acid (D-Malic acid) from Maleic acid when the cells grown in a medium containing citraconic acid are reacted aerobically with Maleic acid in the pH 7.0 phosphate buffer containing 0.1% sodium chloride.
D(+)-Malic acid Preparation Products And Raw materials
Raw materials
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Preparation Products
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Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Nanjing New Thinking Chem Co.,Ltd | +8615896017193 | nanjingxinsi@163.com | China | 217 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5857 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5892 | 58 |
Hebei Weibang Biotechnology Co., Ltd | +8617732866630 | bess@weibangbio.com | China | 18153 | 58 |
Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618092446649 | sarah@tnjone.com | China | 1143 | 58 |
Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
Speranza Chemical Co., Ltd. | +86-86-075521030354 +8618688942810 | sophieliu@speranzachem.com | China | 802 | 55 |
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
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- D(+)-Malic acid Found extensively in various fruits and vegetables, it plays a significant role in metabolic processes, partic....
- Nov 22,2024
View Lastest Price from D(+)-Malic acid manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-11-25 | D( )Malic acid
636-61-3
|
US $0.00-0.00 / KG | 5KG | 99% | 500kg | Speranza Chemical Co., Ltd. | ||
2024-11-22 | D(+)-Malic acid
636-61-3
|
US $0.00 / KG | 1KG | 98.0% | 1000kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
2024-11-19 | D-(+)-Malic acid
636-61-3
|
US $39.00 / mg | 99.62% | 10g | TargetMol Chemicals Inc. |
- D( )Malic acid
636-61-3
- US $0.00-0.00 / KG
- 99%
- Speranza Chemical Co., Ltd.
- D(+)-Malic acid
636-61-3
- US $0.00 / KG
- 98.0%
- WUHAN FORTUNA CHEMICAL CO., LTD
- D-(+)-Malic acid
636-61-3
- US $39.00 / mg
- 99.62%
- TargetMol Chemicals Inc.
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