Methyl indole-3-carboxylate
- CAS No.
- 942-24-5
- Chemical Name:
- Methyl indole-3-carboxylate
- Synonyms
- METHYL 1H-INDOLE-3-CARBOXYLATE;3-Methoxycarbonylindole;methyl indoline-3-carboxylate;INDOLE-3-CARBOXYLIC ACID METHYL ESTER;1H-INDOLE-3-CARBOXYLIC ACID METHYL ESTER;RARECHEM AH BS 0112;3-Carbomethoxyindole;Oxiracetam Impurity 38;3-indole,Methyl forMate;Tropisetron Impurity 23
- CBNumber:
- CB9385281
- Molecular Formula:
- C10H9NO2
- Molecular Weight:
- 175.18
- MDL Number:
- MFCD00189407
- MOL File:
- 942-24-5.mol
- MSDS File:
- SDS
Melting point | 149-152 °C (lit.) |
---|---|
Boiling point | 306.47°C (rough estimate) |
Density | 1.1999 (rough estimate) |
refractive index | 1.5060 (estimate) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | Solid |
pka | 15.42±0.30(Predicted) |
color | Light Pink |
Water Solubility | Slightly soluble methanol and dimethyl sulfoxide. Insoluble in water. |
BRN | 142023 |
CAS DataBase Reference | 942-24-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H402 | |||||||||
Precautionary statements | P501-P273-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36-37/39 | |||||||||
WGK Germany | 3 | |||||||||
HazardClass | IRRITANT | |||||||||
HS Code | 29339900 | |||||||||
NFPA 704 |
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Methyl indole-3-carboxylate price More Price(28)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 395307 | Methyl indole-3-carboxylate 99% | 942-24-5 | 25g | $78.5 | 2023-06-20 | Buy |
TCI Chemical | I0491 | Methyl Indole-3-carboxylate >98.0%(GC) | 942-24-5 | 25g | $35 | 2024-03-01 | Buy |
TCI Chemical | I0491 | Methyl Indole-3-carboxylate >98.0%(GC) | 942-24-5 | 500g | $377 | 2024-03-01 | Buy |
Alfa Aesar | L14516 | Methyl indole-3-carboxylate, 99% | 942-24-5 | 25g | $45.65 | 2024-03-01 | Buy |
Alfa Aesar | L14516 | Methyl indole-3-carboxylate, 99% | 942-24-5 | 100g | $150.65 | 2024-03-01 | Buy |
Methyl indole-3-carboxylate Chemical Properties,Uses,Production
Chemical Properties
light brown amorphous powder
Uses
Reactant for preparation of:
- Nitric oxide synthase (nNOS) inhibitorS
- Protein kinase c alpha (PKCα) inhibitors
- Inhibitors of the C-terminal domain of RNA polymerase II as antitumor agents
- Kinase insert domain receptor (KDR) inhibitors
- Organocatalysts for the anti-Mannich reaction
- Very late antigen-4 (VLA-4) antagonists
- Inhibitors of Human 5-Lipoxygenase
- Serotonin 5-HT4 receptor antagonists
- Hyaluronidase inhibitors
Reactant for:
- Enantioselective Meerwein-Eschenmoser Claisen rearrangement reactions?
Uses
Methyl indole-3-carboxylate is a reagent in the preaparation of oncrasin-1 derivatives which is a novel inhibitor of the C-terminal domain of RNA polymerase II.
Definition
ChEBI: Methyl indole-3-carboxylate is the methyl ester of indole-3-carboxylic acid. It has a role as a metabolite. It is a member of indoles and a methyl ester. It is functionally related to an indole-3-carboxylic acid.
General Description
Methyl indole-3-carboxylate (3-Methoxycarbonylindole, 3-Carbomethoxyindole, Methyl indolyl-3-carboxylate) has been extracted from the marine Streptomyces sp. 060524. Its crystal structure indicates the presence of inter-molecular N-H…O hydrogen bond. It is also obtained during the isolation of sorazinones A and B from Sorangium cellulosum strain Soce895. It undergoes regioselective dibromination with bromine in acetic acid to afford methyl 5,6-dibromoindole-3-carboxylate.
Methyl indole-3-carboxylate Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12450 | 58 |
Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3002 | 58 |
Hebei Shengyang Water Conservancy Engineering Co., Ltd. | +8615373025980 | clara@hbshengyang.com | China | 873 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21668 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29894 | 58 |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 7621 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10828 | 58 |
View Lastest Price from Methyl indole-3-carboxylate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2024-05-11 | Methyl indole-3-carboxylate
942-24-5
|
US $18.00-18.00 / kg | 1kg | 99.9 | 5000 | Hebei Shengyang Water Conservancy Engineering Co., Ltd. | |
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2024-04-22 | Methyl indole-3-carboxylate
942-24-5
|
US $150.00 / kg | 1kg | 99% | 5ton | Hebei Zhuanglai Chemical Trading Co.,Ltd | |
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2023-10-09 | Methyl indole-3-carboxylate
942-24-5
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd |
-
- Methyl indole-3-carboxylate
942-24-5
- US $18.00-18.00 / kg
- 99.9
- Hebei Shengyang Water Conservancy Engineering Co., Ltd.
-
- Methyl indole-3-carboxylate
942-24-5
- US $150.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd
-
- Methyl indole-3-carboxylate
942-24-5
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd