ChemicalBook >> CAS DataBase List >>Tosyl cyanide
Tosyl cyanide
- CAS No.
- 19158-51-1
- Chemical Name:
- Tosyl cyanide
- Synonyms
- 4-Methylbenzenesulfonyl cyanide;P-TOLUENESULFONYL CYANIDE;4-Methylbenzene-1-sulfonyl cyanide;TsCN;osyl cyanide;TOSYL CYANIDE;p-Tosyl cyanide;Tosyl Cyanide (>90%);P-TOLYLSULFONYL CYANIDE;4-TolueenesulfonylCyanide
- CBNumber:
- CB9387346
- Molecular Formula:
- C8H7NO2S
- Molecular Weight:
- 181.21
- MDL Number:
- MFCD00009977
- MOL File:
- 19158-51-1.mol
- MSDS File:
- SDS
Last updated:2025-01-27 09:38:02
| Melting point | 47-50 °C (lit.) |
|---|---|
| Boiling point | 105-106 °C/1 mmHg (lit.) |
| Density | 1.3055 (rough estimate) |
| refractive index | 1.5650 (estimate) |
| Flash point | >230 °F |
| storage temp. | 2-8°C |
| solubility | Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Sparingly), Ethyl Acetate |
| form | crystalline solid |
| color | White |
| BRN | 2048159 |
| Stability | Hygroscopic, Moisture Sensitive |
| CAS DataBase Reference | 19158-51-1(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|---|---|
| Signal word | Danger |
| Hazard statements | H312+H332-H314 |
| Precautionary statements | P260-P271-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338 |
| Hazard Codes | C |
| Risk Statements | 20/21-34 |
| Safety Statements | 26-27-28-36/37/39-45 |
| RIDADR | UN 3261 8/PG 2 |
| WGK Germany | 3 |
| F | 10-21 |
| HazardClass | 8 |
| PackingGroup | III |
| HS Code | 2930909899 |
Tosyl cyanide price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 248835 | p-Toluenesulfonyl cyanide technical grade, 95% | 19158-51-1 | 1g | $86.5 | 2024-03-01 | Buy |
| Sigma-Aldrich | 248835 | p-Toluenesulfonyl cyanide technical grade, 95% | 19158-51-1 | 5g | $230 | 2024-03-01 | Buy |
| TRC | T631000 | TosylCyanide(>90%) | 19158-51-1 | 25g | $400 | 2021-12-16 | Buy |
| AK Scientific | X2932 | p-Toluenesulfonyl cyanide | 19158-51-1 | 25g | $480 | 2021-12-16 | Buy |
| SynQuest Laboratories | 8763-1-X2 | Toluene-4-sulfonyl cyanide 97% | 19158-51-1 | 25g | $615 | 2021-12-16 | Buy |
Tosyl cyanide Chemical Properties,Uses,Production
Chemical Properties
White powder
Uses
p-Toluenesulfonyl cyanide can be used in:
- The preparation of polyfunctional nitriles.
- Free-radical cyanation of B-alkylcatecholboranes.
- The synthesis of 4-hyroxypyridines by hetero-Diels-Alder reaction with 1,3-bis-silyl enol ethers.
Uses
Tosyl cyanide is used in a free-radical cyanation of B-alkylcatecholboranes. Also used as a component in a hetero-Diels-Alder reaction with 1,3-bis-silyl enol ethers leading to 4-hyroxypyridines.
Synthesis Reference(s)
Tetrahedron Letters, 10, p. 3351, 1969 DOI: 10.1017/S0009838800024678
General Description
p-Toluenesulfonyl cyanide is an electron-deficient nitrile. It undergoes hetero-Diels-Alder reaction with silyl enol ether of cyclohexenone to yield hydrolytically sensitive [4+2] adduct. It also undergoes facile [2+3] cycloaddition reaction with azides to form 5-sulfonyl tetrazoles. p-Toluenesulfonyl cyanide also reacts with alcohols in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) or 1,4-diazabicyclo[2.2.2]octane (DABCO) to yield sulfinates.
Tosyl cyanide Preparation Products And Raw materials
Raw materials
Preparation Products
2-Azabicyclo[2.2.1]hept-5-en-3-one
Methyl 3-cyano-4-Methylbenzoate
tert-butyl 3-cyanomorpholine-4-carboxylate
5-KETOHEXANENITRILE
2-FUROYLACETONITRILE
2-Bromothiophene-3-carbonitrile
3-BROMOTHIOPHENE-2-CARBONITRILE
1-Adamantanecarbonitrile
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
(1R,2S,5R)-(-)-MENTHYL (S)-P-TOLUENESULFINATE
1of4
Global( 203)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531157085 | abby@chuanghaibio.com | China | 8808 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12809 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | nickzhang@hangyubiotech.com | China | 10983 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20235 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29730 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-+86-371-66670886 | info@dakenam.com | China | 19805 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21628 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| Zjartschem | +86-571 87238903 | jocelynpan@zjarts.com | CHINA | 988 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
View Lastest Price from Tosyl cyanide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-25 | Tosyl cyanide
19158-51-1
|
US $0.00 / KG | 1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2025-04-23 | Tosyl cyanide
19158-51-1
|
US $1.00 / KG | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-04-22 | Tosyl cyanide
19158-51-1
|
US $70.00-700.00 / kg | 10kg | 0.99 | 20tons | Zibo Hangyu Biotechnology Development Co., Ltd |
-
- Tosyl cyanide
19158-51-1
- US $0.00 / KG
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Tosyl cyanide
19158-51-1
- US $1.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Tosyl cyanide
19158-51-1
- US $70.00-700.00 / kg
- 0.99
- Zibo Hangyu Biotechnology Development Co., Ltd
p-tolylsulfonylforMonitrile
p-Toluenesulfonyl cyanide technical grade, 95%
Toluene-4-sulphonylcyanide,tech
P-TOLYLSULFONYL CYANIDE
p-toluenesulphonyl cyanide
TOSYL CYANIDE
4-Toluenesulfonyl Cyanide
P-TOLUENESULFONYL CYANIDE, TECH., APPROX . 95%
4-TolueenesulfonylCyanide
P-TOLUENE SULFONYL CYANIDE(P-TOLYLSULFNYL CYANIDE)
4-TOLUENESULFONYLCYANIDE, 95+%
toluene-4-sulfonyl cyanide
p-Tolylsulfonyl cyanide, Tosyl cyanide
Benzenesulfonylcyanide, 4-Methyl-
Toluene-4-sulphonyl cyanide
Tosyl cyanide, 4-Methylbenzenesulphonyl cyanide
Tosyl cyanide, 4-Methylbenzenesulphonyl cyanide, 4-(Cyanosulphonyl)toluene
p-Toluenesulfonyl cyanide
p-Tosyl cyanide
Toluene-4-sulfonyl cyanide 98%
(4-methylphenyl)sulfonylformonitrile
Tosyl cyanide ISO 9001：2015 REACH
Tosyl Cyanide (>90%)
osyl cyanide
P-TOLUENESULFONYL CYANIDE
4-Methylbenzenesulfonyl cyanide
4-Methylbenzene-1-sulfonyl cyanide
TsCN
19158-51-1
Cyanides/Nitriles
Organic Building Blocks
Nitrogen Compounds
Building Blocks
C8 to C9
Building Blocks
C8 to C9
Chemical Synthesis
Cyanides/Nitriles
Nitrogen Compounds
Organic Building Blocks