ChemicalBook >> CAS DataBase List >>2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile
2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile
![2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile Structure](CAS/20180723/GIF/177028-90-9.gif)
- CAS No.
- 177028-90-9
- Chemical Name:
- 2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile
- Synonyms
- WAY-298592;AChE-IN-27;AChE-IN-27, 10 mM in DMSO;2-Amino-5-oxo-4-(p-tolyl)-4H,5H-pyrano[3,2-c]chromene-3-carbonitrile;2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile;4H,5H-Pyrano[3,2-c][1]benzopyran-3-carbonitrile, 2-amino-4-(4-methylphenyl)-5-oxo-;neurological diseases,alzheimer's disease,WAY 298592,Inhibitor,dementia,myasthenia gravis,Cholinesterase (ChE),inhibit,ataxia,WAY298592
- CBNumber:
- CB94228740
- Molecular Formula:
- C20H14N2O3
- Molecular Weight:
- 330.34
- MDL Number:
- MFCD00565058
- MOL File:
- 177028-90-9.mol
Last updated:2025-04-17 18:22:24
| Melting point | 255 °C |
|---|---|
| Boiling point | 641.0±55.0 °C(Predicted) |
| Density | 1.40±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO : 100 mg/mL (302.72 mM; ultrasonic and warming and heat to 60°C) |
| pka | 3.15±0.40(Predicted) |
| form | Solid |
| color | White to off-white |
2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile Chemical Properties,Uses,Production
Uses
AChE-IN-27 (compound 8c) is an AChE inhibitor (IC50=0.19 μM). AChE-IN-27 can be used in studies of neurological diseases such as alzheimer's disease, dementia, ataxia and myasthenia gravis[1].
References
[1] Bouazizi Y, et al. Synthesis of new 3, 4-dihydropyrano [c] chromene derivatives and their evaluation as acetyl cholinesterase inhibitors[J]. European Journal of Chemistry, 2014, 5(3): 457-462.
2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile Suppliers
Global( 19)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38630 | 58 | |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71829 | 60 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 6345 | 55 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 62072 | 58 |
| Changzhou Bojia Biomedical Technology Co., Ltd. | 2122619822 | czbjpharma@126.com | China | 18478 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24642 | 58 |
| Nanjing Tengyi Biotechnology Co., Ltd | 025-58851786 17714337195 | sales@tybiochem.com | China | 7165 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11973 | 58 |
View Lastest Price from 2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | AChE-IN-27
177028-90-9
|
US $46.00-173.00 / mg | 98.54% | 10g | TargetMol Chemicals Inc. |
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- AChE-IN-27
177028-90-9
- US $46.00-173.00 / mg
- 98.54%
- TargetMol Chemicals Inc.
2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile
WAY-298592
neurological diseases,alzheimer's disease,WAY 298592,Inhibitor,dementia,myasthenia gravis,Cholinesterase (ChE),inhibit,ataxia,WAY298592
2-Amino-5-oxo-4-(p-tolyl)-4H,5H-pyrano[3,2-c]chromene-3-carbonitrile
4H,5H-Pyrano[3,2-c][1]benzopyran-3-carbonitrile, 2-amino-4-(4-methylphenyl)-5-oxo-
AChE-IN-27
AChE-IN-27, 10 mM in DMSO
177028-90-9