(+/-)-MUSCARINE CHLORIDE

CAS No.
2936-25-6
Chemical Name:
(+/-)-MUSCARINE CHLORIDE
Synonyms
(+)-MUSCARINE;Muscarinic chloride;DL-MUSCARINCHLORIDE);DL-MUSCARINECHLORIDE;(+/-)-MUSCARINE CHLORIDE;(±)-Muscarine chloride hydrate;(+/-)-muscarine chloride approx. 95%;(+/-)-MUSCARINE CHLORIDE SYNTHETIC >99%;(±)-Muscarine chloride hydrate in methanol;Tetrahydro-4α-hydroxy-N,N,N,5β-tetramethyl-2β-furanmethanaminium
CBNumber:
CB9427721
Molecular Formula:
C9H20ClNO2
Molecular Weight:
209.71
MDL Number:
MFCD00055067
MOL File:
2936-25-6.mol
Last updated:2024-11-19 23:02:33

(+/-)-MUSCARINE CHLORIDE Properties

storage temp. room temp
solubility deionized water: ≥20mg/mL
form powder
color white
FDA UNII 7T101UWZ5W

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H319
Precautionary statements  P264-P270-P280-P301+P312-P305+P351+P338-P337+P313
Hazard Codes  Xn
Risk Statements  22-36
Safety Statements  26-36
RIDADR  1544
WGK Germany  3
HazardClass  6.1(a)
PackingGroup  II

(+/-)-MUSCARINE CHLORIDE price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich M104 (±)-Muscarine chloride hydrate ≥98% (HPLC) 2936-25-6 5mg $167 2024-03-01 Buy
Sigma-Aldrich M104 (±)-Muscarine chloride hydrate ≥98% (HPLC) 2936-25-6 25mg $537 2024-03-01 Buy
TRC M814005 (+/-)-MuscarineChloride 2936-25-6 25mg $1175 2021-12-16 Buy
American Custom Chemicals Corporation HBL0000023 (+/-)-MUSCARINE CHLORIDE 95.00% 2936-25-6 5MG $578 2021-12-16 Buy
American Custom Chemicals Corporation HBL0000023 (+/-)-MUSCARINE CHLORIDE 95.00% 2936-25-6 10MG $883.49 2021-12-16 Buy
Product number Packaging Price Buy
M104 5mg $167 Buy
M104 25mg $537 Buy
M814005 25mg $1175 Buy
HBL0000023 5MG $578 Buy
HBL0000023 10MG $883.49 Buy

(+/-)-MUSCARINE CHLORIDE Chemical Properties,Uses,Production

Description

Muscarine is a natural alkaloid that is found in a number of wild mushrooms. Despite the fact that muscarine does not have any therapeutic value, it is of interest because of its expressed toxic properties, which made it one of the first systematically studied cholinomimetic substances. This compound was an underlying classification of cholinergic muscarinic receptors. The action of muscarine is similar to that of acetylcholine on peripheral autonomic effector organs, and atropine is an antagonist to it. Unlike acetylcholine, muscarine does not act on nicotinic receptors.

Uses

(+/-)-Muscarine Chloride is a muscarinic acteylcholine receptor agonist.

Biochem/physiol Actions

Muscarine is a potent agonist than acetylcholine and is not susceptible to degradation by cholinesterases. Muscarine administration results in muscle spasm especially in gut, bronchus and uterus.

Synthesis

Muscarine, 2-methyl-3-hydroxy-5-(N,N,N-trimethylammonium) methylentetrahydrofuran chloride (13.1.14), was first isolated from the poisonous mushrooms Amanita muscaria. It can be synthesized in various ways from completely different substances [16¨C24], particularly from 2,5-dimethyl-3-carboxymethylflurane, which undergoes a Curtius reaction, i.e. successive reactions with hydrazine and further with nitrous acid in isopropyl alcohol, which forms the urethane (13.1.9), the acidic hydrolysis of which gives 2,5-dimethyl-2H-furane-3 (13.1.10). Allylic bromination of this gives 2- methyl-5-bromomethyl-2H-furanone-3 (13.1.11), which is reacted with dimethylamine, forming 2-methyl-5-dimethylaminomethyl-2H-fluranone-3 (13.1.12). Reducing this compound leads to formation of 2-methyl-3-hydroxy-5-dimethylaminomethyltetrahydroflurane (13.1.13), the reaction of which with methyl chloride gives muscarine (13.1.14) as a mixture of stereoisomers.

Synthesis_2936-25-6

(+/-)-MUSCARINE CHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

(+/-)-MUSCARINE CHLORIDE Suppliers

Global( 22)Suppliers
Supplier Tel Email Country ProdList Advantage
Zibo Hangyu Biotechnology Development Co., Ltd
+86-0533-2185556 +8617865335152 Mandy@hangyubiotech.com China 10986 58
TargetMol Chemicals Inc.
+8613564774135 zijue.cai@tsbiochem.com United States 19885 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15839 69
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51456 80
Shanghai Moqi Biological Technology Co., LTD 021-38218169 13341702378 190129269@qq.com China 9126 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24647 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11974 58
Shandong Mopai Biotechnology Co., Ltd 13070690626 admin@mopaikeji.com China 10756 58
4008-099-669 23419001name@qq.com CHINA 71677 58
United States Biological -- sales@advtechind.com United States 6075 58

View Lastest Price from (+/-)-MUSCARINE CHLORIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(±)-Muscarine chloride pictures 2024-11-19 (±)-Muscarine chloride
2936-25-6
US $0.00-0.00 / mg 10g TargetMol Chemicals Inc.
(+)-MUSCARINE (+/-)-MUSCARINE CHLORIDE TETRAHYDRO-4-HYDROXY-N,N,N,5-TETRAMETHYL-2-FURANMETHANAMMONIUM CHLORIDE (+/-)-muscarine chloride approx. 95% (+/-)-MUSCARINE CHLORIDE SYNTHETIC >99% DL-MUSCARINECHLORIDE DL-MUSCARINCHLORIDE) (-)-α-[[(2R)-Tetrahydro-4α-hydroxy-5β-methylfuran]-2β-yl]-N,N,N-trimethylmethanaminium (2R)-Tetrahydro-4α-hydroxy-N,N,N,5β-tetramethyl-2β-furanmethanaminium (2R,4S,5R)-Tetrahydro-4-hydroxy-5,N,N,N-tetramethyl-2-furanmethanaminium [(4α-Hydroxy-5β-methyltetrahydrofuran-2β-yl)methyl]trimethylaminium Tetrahydro-4α-hydroxy-N,N,N,5β-tetramethyl-2β-furanmethanaminium rac-(2S*)-Tetrahydro-4β*-hydroxy-N,N,N,5α*-tetramethyl-2α*-furanmethanaminium 2-Furanmethanaminium, tetrahydro-4-hydroxy-N,N,N,5-tetramethyl-, chloride, (2alpha,4beta,5alpha)-(+-)- (±)-Muscarine chloride hydrate Tetrahydro-4-hydroxy-N,N,N,5-tetramethyl-2-furanmethanammonium chloride hydrate Muscarinic chloride (±)-Muscarine chloride hydrate in methanol 2936-25-6 C9H20NO2