OXONIC ACID POTASSIUM SALT
- CAS No.
- 2207-75-2
- Chemical Name:
- OXONIC ACID POTASSIUM SALT
- Synonyms
- OXO;OTERACIL POTASSIUM;NOX4;POTASSIUM OXONATE;Potassium otastat;oxonic acid potassium;kox;KOX-1;Anti-KOX-1;otassiuM oxonate
- CBNumber:
- CB9435346
- Molecular Formula:
- C4H2KN3O4
- Molecular Weight:
- 195.17
- MDL Number:
- MFCD00010565
- MOL File:
- 2207-75-2.mol
- MSDS File:
- SDS
| Melting point | 300 °C(lit.) |
|---|---|
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Aqueous Base (Slightly), Water (Slightly, Heated, Sonicated) |
| form | Powder |
| color | White |
| biological source | rabbit |
| Water Solubility | Soluble in hot water. |
| CAS DataBase Reference | 2207-75-2(CAS DataBase Reference) |
| FDA UNII | 4R7FFA00RX |
| UNSPSC Code | 12352203 |
| NACRES | NA.41 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| RTECS | RR4580000 |
| HS Code | 29349990 |
OXONIC ACID POTASSIUM SALT price More Price(49)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 156124 | Oxonic acid potassium salt 97% | 2207-75-2 | 5g | $44 | 2024-03-01 | Buy |
| Sigma-Aldrich | 156124 | Oxonic acid potassium salt 97% | 2207-75-2 | 25g | $212 | 2024-03-01 | Buy |
| Sigma-Aldrich | SAB5700950 | Anti- NOX4 antibody produced in rabbit | 2207-75-2 | 100UL | $389 | 2023-06-20 | Buy |
| Sigma-Aldrich | HPA015475 | Anti-NOX4 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 2207-75-2 | 25μL | $282 | 2023-06-20 | Buy |
| Sigma-Aldrich | HPA015475 | Anti-NOX4 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 2207-75-2 | 100μL | $547 | 2023-06-20 | Buy |
OXONIC ACID POTASSIUM SALT Chemical Properties,Uses,Production
Description
Oxonic acid is a uricase inhibitor that prevents metabolism and excretion of uric acid and induces embryotoxicity and nephrotoxicity in rats. It is a component of S-1, a mixture containing a prodrug of the antitumor agent 5-fluorouracil (5-FU; ), that suppresses the gastrointestinal toxicity of 5-FU without inhibiting its antitumor activity in rats. Formulations containing oxonic acid have been used to treat gastric, pancreatic, lung, head, neck, and breast carcinomas.
Chemical Properties
Off-White Solid
Uses
Oxonic acid potassium salt is an inhibitor of uricase. The product from Sigma has been used for the inhibition of 5-fluorouracil-induced gastrointestinal toxicity without the loss of its antitumor activity in rats. It has also been used to induce hyperuricemia in rats; as it inhibits uric acid metabolism.
Uses
Antitumor effect potentiator and antitumor agent
Definition
ChEBI: Potassium 2,6-dihydroxytriazinecarboxylate is an organic molecular entity.
in vivo
Potassium oxonate can be used in animal modeling to create hyperuricemia models. After metabolism, Potassium oxonate primarily distributes within the cells of the small intestine. In the gastrointestinal tract, Potassium oxonate is converted to cyanuric acid via two pathways: the first involves direct conversion by gut microbiota in the cecum, and the second involves conversion through xanthine oxidase, or after degradation by stomach acid into 5-aza-uracil (5-AZU), followed by conversion through aldehyde oxidase[3].
Administration: 300 mg/kg ? i.p. ? once daily for 14 days
(2) On day 15, the mice are fasted for 12 hours, anesthetized with pentobarbital sodium, and then all sacrificed.
(3) Collect mouse blood samples in 2mL EP tubes, centrifuge (3000rpm, 4°C, 10min), and then store at -80°C for biochemical determination.
(4) The kidney tissue is quickly removed, weighed and divided into two parts, one part was fixed in 4% paraformaldehyde for histopathological examination, and the other part is stored at -80°C for further biochemical determination.
Histological changes: Inconspicuous boundaries between adjacent proximal tubule cells, swelling and proximal tubule necrosis.
OXONIC ACID POTASSIUM SALT Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29730 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21628 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| Hubei XinRunde Chemical Co., Ltd. | +8615102730682 | bruce@xrdchem.cn | CHINA | 566 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29858 | 58 |
| Jinan Jianfeng Chemical Co., Ltd | +86-0531-88110457 +86-15562555968 | info@pharmachemm.com | China | 334 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6383 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
View Lastest Price from OXONIC ACID POTASSIUM SALT manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-27 | Oxonic acid potassium salt
2207-75-2
|
US $0.00-0.00 / Kg/Drum | 1KG | 99%min | 500kg | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2025-03-21 | Oteracil potassium
2207-75-2
|
US $120.00 / KG | 1KG | 99.99% | 100KG | Shandong Xuhuang New material CoLTD | |
 |
2024-11-19 | Potassium oxonate
2207-75-2
|
US $44.00 / mg | 99.86% | 10g | TargetMol Chemicals Inc. |
-
- Oxonic acid potassium salt
2207-75-2
- US $0.00-0.00 / Kg/Drum
- 99%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Oteracil potassium
2207-75-2
- US $120.00 / KG
- 99.99%
- Shandong Xuhuang New material CoLTD
-
- Potassium oxonate
2207-75-2
- US $44.00 / mg
- 99.86%
- TargetMol Chemicals Inc.