ANTI-HUMAN FIBROBLAST SURFACE PROTEIN
- CAS No.
- Chemical Name:
- ANTI-HUMAN FIBROBLAST SURFACE PROTEIN
- Synonyms
- ANTI-HUMAN FIBROBLAST SURFACE PROTEIN;Monoclonal Anti-Fibroblast Surface Protein antibody produced in mouse
- CBNumber:
- CB9441356
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00164646
- MOL File:
- Mol file
ANTI-HUMAN FIBROBLAST SURFACE PROTEIN Chemical Properties,Uses,Production
Uses
Monoclonal anti-fibroblast surface protein antibody can be used in flow cytometry of human fibroblasts and monocytes. It is also useful in immunoblotting and western blotting.
General Description
Monoclonal Anti-Human Fibroblast Surface Protein (mouse IgM isotype) is derived from the 1B10 hybridoma1 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with cultured human thymic fibroblasts. Human fibroblast surface protein is a fibroblast antigen that is expressed mainly on human synovial, foreskin and thymic fibroblasts and is absent on human epithelial cells and lymphocytes.
Biochem/physiol Actions
Monoclonal Anti-Fibroblast Surface Protein antibody is also used to remove fibroblasts from human cultured cells by inhibiting fibroblasts adherence to the culture vessel or by cytotoxic effect in the presence of rabbit complement. In addition, apart from the functional significance of cells characteristics, the characterization of cell lines is important for correlation of cultures with tissue origin, identification of the lineage to which the cells belong or the precursor status of the cells. Monoclonal antibodies to fibroblast surface protein should provide a powerful tool for control of fibroblast growth in a variety of human cell culture systems, such as thymic epithelial (TE) cell cultures allowing the growth of highly enriched populations of the TE cells.
ANTI-HUMAN FIBROBLAST SURFACE PROTEIN Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-HUMAN FIBROBLAST SURFACE PROTEIN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |