Chelidonic acid
- CAS No.
- 99-32-1
- Chemical Name:
- Chelidonic acid
- Synonyms
- AI3-19253;JERVA ACID;γ-Pyrone-2;jervaicacid;compoundxi*;AKOS AUF02028;JERVASIC ACID;CHELIDONIC ACID;TIMTEC-BB SBB000242;CHELIDONIC ACID(RG)
- CBNumber:
- CB9441381
- Molecular Formula:
- C7H4O6
- Molecular Weight:
- 184.1
- MDL Number:
- MFCD00006577
- MOL File:
- 99-32-1.mol
- MSDS File:
- SDS
| Melting point | 265 °C (dec.) (lit.) |
|---|---|
| Boiling point | 238.02°C (rough estimate) |
| Density | 1.4880 (rough estimate) |
| refractive index | 1.5600 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO: 1 mg/ml; DMSO:PBS (pH 7.2) (1:6): 0.14 mg/ml |
| form | Solid |
| pka | 1.26±0.40(Predicted) |
| color | Gray to brown |
| Water Solubility | 14.3g/L(25 ºC) |
| Merck | 13,2060 |
| BRN | 163607 |
| InChIKey | PBAYDYUZOSNJGU-UHFFFAOYSA-N |
| LogP | -0.746 (est) |
| CAS DataBase Reference | 99-32-1(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | T33U4W5K6O |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UP7350000 | |||||||||
| HS Code | 29329990 | |||||||||
| NFPA 704 |
|
Chelidonic acid price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 382272 | Chelidonic acid 98% | 99-32-1 | 5g | $193 | 2024-03-01 | Buy |
| Sigma-Aldrich | 382272 | Chelidonic acid 98% | 99-32-1 | 25g | $244.8 | 2024-03-01 | Buy |
| TRC | E588808 | 4-Oxo-4h-pyran-2,6-dicarboxylicAcid | 99-32-1 | 500mg | $75 | 2021-12-16 | Buy |
| TRC | E588808 | 4-Oxo-4h-pyran-2,6-dicarboxylicAcid | 99-32-1 | 100mg | $60 | 2021-12-16 | Buy |
| ApexBio Technology | C7060 | Chelidonic acid | 99-32-1 | 100mg | $60 | 2021-12-16 | Buy |
Chelidonic acid Chemical Properties,Uses,Production
Configuration Method
Chelidonic acid is supplied as a crystalline solid. A stock solution may be made by dissolving thechelidonic acid in the solvent of choice, which should be purged with an inert gas. Chelidonic acid is soluble in the organic solvent DMSO at approximately 1 mg/ml concentration. Chelidonic acid is sparingly soluble in aqueous buffers. For maximum solubility in aqueous buffers,chelidonic acid should first be dissolved in DMSO and then diluted with the aqueous buffer of choice. Chelidonic acid has a solubility of approximately 0.14 mg/ml in a 1:6 solution of DMSO: PBS(pH 7.2) using this method. We do not recommend storing the aqueous solution for more than one day.
Uses
Chelidonic acid is suitable for use a in homogeneous preparation of native dihydrodipicolinate synthase from pea. It may be used as endocyclic oxygen-containing ligand in the synthesis of aqua[bis(2-pyridylmethyl)amine][chelidonato(1.5-)]-copper(II) chelidonate(0.5-) monohydrate.
Definition
ChEBI: Chelidonic acid is a carbonyl compound and a member of pyrans.
General Description
Chelidonic acid (CA) is a γ-pyrone. It is reported as constituent of the rhizome of Chelidonium majus L. It has many pharmacological effects, such as mild analgesic and antimicrobial effects. Therapeutic potential of CA for the treatment of intestinal inflammation has been investigated. CA is reported as inhibitor of the rat brain glutamate decarboxylase. Biosynthesis of CA in cell suspension cultures of Leucojum aestivum has been studied.
Purification Methods
The acid crystallises from aqueous EtOH. Dry it first at 100o/2hours, then at 160o to constant weight to remove water of crystallisation. It decarboxylates at 220-230o in a vacuum. [Riegel & Zwilgmeyer Org Synth Coll Vol II 126 1943, Beilstein 18 H 490, 18/8 V 646.]
Chelidonic acid Preparation Products And Raw materials
Chelidonic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Qingdao Yonghefeng Economic and Trade Co., Ltd. | +86-13375559818 +86-13375559818 | cfy69@163.com | China | 195 | 58 |
| XIAMEN AMITY INDUSTRY AND TRADE CO., LTD. | +8618950047208 | ellena@amitychem.com | China | 43416 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | 1022@dideu.com | China | 3882 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29871 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Nanjing jinheyou Trading Co., Ltd. | 15705188088 | admin@jheyou.com | CHINA | 1268 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
View Lastest Price from Chelidonic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-17 | Chelidonic acid
99-32-1
|
US $33.00-48.00 / mg | ≥95% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-08-25 | Chelidonic acid
99-32-1
|
US $0.00-0.00 / KG | 1KG | 99.0% | 1000KG | Shaanxi Dideu Medichem Co. Ltd | |
 |
2022-02-19 | 4-oxo-4H-pyran-2,6-dicarboxylic acid
99-32-1
|
US $0.00 / KG | 1KG | 98.8% | 100 tons | Honest Joy Holdings Limited
|
-
- Chelidonic acid
99-32-1
- US $33.00-48.00 / mg
- ≥95%
- TargetMol Chemicals Inc.
-
- Chelidonic acid
99-32-1
- US $0.00-0.00 / KG
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- 4-oxo-4H-pyran-2,6-dicarboxylic acid
99-32-1
- US $0.00 / KG
- 98.8%
- Honest Joy Holdings Limited