6-Aminonicotinic acid
- CAS No.
- 3167-49-5
- Chemical Name:
- 6-Aminonicotinic acid
- Synonyms
- 3-Pyridinecarboxylic acid, 6-amino-;6- aMinoacid;6-AMinonicotinic a;TIMTEC-BB SBB004186;RARECHEM AL BO 1167;6-Aminonicotinc Acid;6-AMINONICOTINIC ACID;Nicotinic acid, 6-amino-;2-Amino-5-carboxypyridine;6-Aminonicotinic acid 98%
- CBNumber:
- CB9449781
- Molecular Formula:
- C6H6N2O2
- Molecular Weight:
- 138.12
- MDL Number:
- MFCD00006326
- MOL File:
- 3167-49-5.mol
- MSDS File:
- SDS
Melting point | >300 °C (lit.) |
---|---|
Boiling point | 253.51°C (rough estimate) |
Density | 1.3471 (rough estimate) |
refractive index | 1.5100 (estimate) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
form | Powder |
pka | 2.86±0.10(Predicted) |
color | White to beige |
Water Solubility | ca 1.0 g/L (20 ºC) |
Merck | 14,456 |
BRN | 115992 |
CAS DataBase Reference | 3167-49-5(CAS DataBase Reference) |
FDA UNII | 9VR2O1OK60 |
NIST Chemistry Reference | Nicotinic acid, 6-amino-(3167-49-5) |
EPA Substance Registry System | 3-Pyridinecarboxylic acid, 6-amino- (3167-49-5) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
Hazard Codes | Xi,T | |||||||||
Risk Statements | 36/37/38-23/24/25 | |||||||||
Safety Statements | 22-24/25-45-36/37/39-26 | |||||||||
WGK Germany | 3 | |||||||||
TSCA | T | |||||||||
HazardClass | IRRITANT | |||||||||
HS Code | 29333990 | |||||||||
NFPA 704 |
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6-Aminonicotinic acid price More Price(35)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 216879 | 6-Aminopyridine-3-carboxylic acid 97% | 3167-49-5 | 5g | $45.5 | 2024-03-01 | Buy |
Sigma-Aldrich | 216879 | 6-Aminopyridine-3-carboxylic acid 97% | 3167-49-5 | 1g | $24.9 | 2023-06-20 | Buy |
TCI Chemical | A1486 | 6-Aminonicotinic Acid >98.0%(T) | 3167-49-5 | 1g | $41 | 2024-03-01 | Buy |
TCI Chemical | A1486 | 6-Aminonicotinic Acid >98.0%(T) | 3167-49-5 | 5g | $123 | 2024-03-01 | Buy |
Alfa Aesar | A11223 | 6-Aminonicotinic acid, 98% | 3167-49-5 | 5g | $99.65 | 2024-03-01 | Buy |
6-Aminonicotinic acid Chemical Properties,Uses,Production
Chemical Properties
Light yellow Cryst
Uses
6-Aminopyridine-3-carboxylic acid (6-Aminonicotinic acid) was used in the preparation of resin-bound 2-aminoazine.
Uses
Antiproliferative
Definition
ChEBI: An aminonicotinic acid in which the amino group is situated at position 6 of the pyridine ring.
Application
6-Aminonicotinic acid is an inhibitor of bacterial DNA gyrase and topoisomerase IV. It has been shown to inhibit the growth of a number of bacteria, including E. coli K-12, with potent inhibitory activity against these enzymes. It binds to the active sites on these enzymes and prevents them from working. The detection time for 6-aminonicotinic acid is about 3 hours after exposure. It has been shown to be more potent than other inhibitors of bacterial DNA gyrase and topoisomerase IV such as 2,4-diaminopyrimidine (2,4DAP).
General Description
Electrosynthesis of 6-aminopyridine-3-carboxylic acid (6-aminonicotinic acid) by electrochemical reduction of 2-amino-5-bromo and 2-amino-5-chloropyridine in the presence of CO2 at silver electrode has been reported.
Purification Methods
Crystallise the acid from aqueous acetic acid. Dry it in vacuo at 70o. [Beilstein 22 III/IV 6726.]
6-Aminonicotinic acid Preparation Products And Raw materials
Raw materials
1of4
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Nanjing Shunxiang Pharmaceutical Technology Co.,Ltd. | +86-86-02586819868 +8613913839793 | sales@jinchemical.com | China | 23 | 58 |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-18789408387 | 1057@dideu.com | China | 3958 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5892 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20286 | 58 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29881 | 58 |
Shanghai Arbor Chemical Co., Ltd. | 021-60451682 | act@arborchemical.com | CHINA | 904 | 58 |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
View Lastest Price from 6-Aminonicotinic acid manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-11-19 | 6-Aminonicotinic acid
3167-49-5
|
US $29.00 / g | 99.94% | 10g | TargetMol Chemicals Inc. | |||
2024-10-11 | 6-Aminonicotinic Acid
3167-49-5
|
US $10.00 / kg | 1kg | 98% | 10 ton | Hebei Chuanghai Biotechnology Co,.LTD | ||
2024-07-08 | 6-Aminonicotinic acid
3167-49-5
|
US $1.00 / Kg | 1Kg | 98% | 20T | Shaanxi Dideu Medichem Co. Ltd |
- 6-Aminonicotinic acid
3167-49-5
- US $29.00 / g
- 99.94%
- TargetMol Chemicals Inc.
- 6-Aminonicotinic Acid
3167-49-5
- US $10.00 / kg
- 98%
- Hebei Chuanghai Biotechnology Co,.LTD
- 6-Aminonicotinic acid
3167-49-5
- US $1.00 / Kg
- 98%
- Shaanxi Dideu Medichem Co. Ltd