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6-Aminonicotinic acid

CAS No.
3167-49-5
Chemical Name:
6-Aminonicotinic acid
Synonyms
3-Pyridinecarboxylic acid, 6-amino-;6- aMinoacid;6-AMinonicotinic a;TIMTEC-BB SBB004186;RARECHEM AL BO 1167;6-Aminonicotinc Acid;6-AMINONICOTINIC ACID;Nicotinic acid, 6-amino-;2-Amino-5-carboxypyridine;6-Aminonicotinic acid 98%
CBNumber:
CB9449781
Molecular Formula:
C6H6N2O2
Molecular Weight:
138.12
MDL Number:
MFCD00006326
MOL File:
3167-49-5.mol
MSDS File:
SDS
Last updated:2024-11-19 23:02:33

6-Aminonicotinic acid Properties

Melting point >300 °C (lit.)
Boiling point 253.51°C (rough estimate)
Density 1.3471 (rough estimate)
refractive index 1.5100 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
form Powder
pka 2.86±0.10(Predicted)
color White to beige
Water Solubility ca 1.0 g/L (20 ºC)
Merck 14,456
BRN 115992
CAS DataBase Reference 3167-49-5(CAS DataBase Reference)
FDA UNII 9VR2O1OK60
NIST Chemistry Reference Nicotinic acid, 6-amino-(3167-49-5)
EPA Substance Registry System 3-Pyridinecarboxylic acid, 6-amino- (3167-49-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi,T
Risk Statements  36/37/38-23/24/25
Safety Statements  22-24/25-45-36/37/39-26
WGK Germany  3
TSCA  T
HazardClass  IRRITANT
HS Code  29333990
NFPA 704
0
1 0

6-Aminonicotinic acid price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 216879 6-Aminopyridine-3-carboxylic acid 97% 3167-49-5 5g $45.5 2024-03-01 Buy
Sigma-Aldrich 216879 6-Aminopyridine-3-carboxylic acid 97% 3167-49-5 1g $24.9 2023-06-20 Buy
TCI Chemical A1486 6-Aminonicotinic Acid >98.0%(T) 3167-49-5 1g $41 2024-03-01 Buy
TCI Chemical A1486 6-Aminonicotinic Acid >98.0%(T) 3167-49-5 5g $123 2024-03-01 Buy
Alfa Aesar A11223 6-Aminonicotinic acid, 98% 3167-49-5 5g $99.65 2024-03-01 Buy
Product number Packaging Price Buy
216879 5g $45.5 Buy
216879 1g $24.9 Buy
A1486 1g $41 Buy
A1486 5g $123 Buy
A11223 5g $99.65 Buy

6-Aminonicotinic acid Chemical Properties,Uses,Production

Chemical Properties

Light yellow Cryst

Uses

6-Aminopyridine-3-carboxylic acid (6-Aminonicotinic acid) was used in the preparation of resin-bound 2-aminoazine.

Uses

Antiproliferative

Definition

ChEBI: An aminonicotinic acid in which the amino group is situated at position 6 of the pyridine ring.

Application

6-Aminonicotinic acid is an inhibitor of bacterial DNA gyrase and topoisomerase IV. It has been shown to inhibit the growth of a number of bacteria, including E. coli K-12, with potent inhibitory activity against these enzymes. It binds to the active sites on these enzymes and prevents them from working. The detection time for 6-aminonicotinic acid is about 3 hours after exposure. It has been shown to be more potent than other inhibitors of bacterial DNA gyrase and topoisomerase IV such as 2,4-diaminopyrimidine (2,4DAP).

General Description

Electrosynthesis of 6-aminopyridine-3-carboxylic acid (6-aminonicotinic acid) by electrochemical reduction of 2-amino-5-bromo and 2-amino-5-chloropyridine in the presence of CO2 at silver electrode has been reported.

Purification Methods

Crystallise the acid from aqueous acetic acid. Dry it in vacuo at 70o. [Beilstein 22 III/IV 6726.]

39658-41-8
3167-49-5
Synthesis of 6-Aminonicotinic acid from Ethyl 6-aminonicotinate
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View Lastest Price from 6-Aminonicotinic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
6-Aminonicotinic acid pictures 2024-11-19 6-Aminonicotinic acid
3167-49-5
US $29.00 / g 99.94% 10g TargetMol Chemicals Inc.
6-Aminonicotinic Acid pictures 2024-10-11 6-Aminonicotinic Acid
3167-49-5
US $10.00 / kg 1kg 98% 10 ton Hebei Chuanghai Biotechnology Co,.LTD
6-Aminonicotinic acid pictures 2024-07-08 6-Aminonicotinic acid
3167-49-5
US $1.00 / Kg 1Kg 98% 20T Shaanxi Dideu Medichem Co. Ltd
6-amino-3-pyridinecarboxylicaci 6-AMINONICOTINIC ACID 6-AMINOPYRIDINE-3-CARBOXYLIC ACID 2-AMINO-5-PYRIDINECARBOXYLIC ACID 2-AMINOPYRIDINE-5-CARBOXYLIC ACID RARECHEM AL BO 1167 TIMTEC-BB SBB004186 2-Amino-5-carboxypyridine 6-Amino-3-pyridinecaboxylic acid 6-Aminonicotinic acid;6-Aminopyridine-3-carboxylic acid 6-AMINO-3-PYRIDINE CARBOXLIC ACID 6-Aminonicotinic acid, 98+% 2-Aminopyridine-5-carboxylic acid(6-Aminonicotinic acid) 6-Amino-3-pyridinecarboxylic Acid 6-Aminopyridine-3-carboxylic acid ,98% 6-Aminonicotinic acid 98% 3-Pyridinecarboxylicacid,6-amino-(9CI) 6-Aminonicotinc Acid 2-Aminopyridine-5-carboxylic acid, 6-Aminopyridine-3-carboxylic acid, 6-Amino-3-carboxypyridine 6-aMinopyridine-3-carbo×ylic acid 6-AMinonicotinic a 2-Aminopyridine-5-carboxylic acid, 6-Aminopyridine-3-carboxylic acid, 2-Amino-5-carboxypyridine 6- aMinoacid Nicotinic acid, 6-amino- 2-AMINO-5-CARBOXAMIDE PYRIDINE Nicotinic acid, 6-amino- (8CI) 6-Aminonicotinic Acid > 6-Aminonicotinic acid USP/EP/BP 3-Pyridinecarboxylic acid, 6-amino- 6-Aminonicotinic acid?New 3167-49-5 167-49-5 3617-49-5 C6 Building Blocks CARBOXYLIC ACID Heterocyclic Building Blocks Pyridines Aromatics Chemical Amines Heterocycles Carboxylic Acids AMINOACID Amines blocks Carboxes Pyridines Pyridine pyridine derivative Pyridines, Pyrimidines, Purines and Pteredines pharmacetical Pyridine series Carboxylic Acids Organic acids