ChemicalBook >> CAS DataBase List >>N-Oleoyl Leucine

N-Oleoyl Leucine

N-Oleoyl Leucine structure

CAS No.: 136560-76-4

Chemical Name:: N-Oleoyl Leucine

Synonyms: N-Oleoyl Leucine;NOleoyl Leucine,N Oleoyl Leucine;N-[(9Z)-1-oxo-9-octadecen-1-yl]-L-leucine;L-Leucine, N-[(9Z)-1-oxo-9-octadecen-1-yl]-

CBNumber:: CB94667044

Molecular Formula:: C24H45NO3

Molecular Weight:: 395.62

MDL Number:

MOL File:: 136560-76-4.mol

Last updated:2024-11-06 19:41:26

Request For Quotation

N-Oleoyl Leucine Properties

Boiling point	560.0±43.0 °C(Predicted)
Density	0.942±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMF: 10 mg/ml; DMSO: 12 mg/ml; Ethanol: 12 mg/ml; Ethanol:PBS (pH 7.2) (1:4): 200 μg/ml
pka	3.67±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS07

Signal word

Danger

Hazard statements

H225-H319

Precautionary statements

P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501

NFPA 704

	3
2		0

N-Oleoyl Leucine price More Price(3)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	20064	N-Oleoyl Leucine ≥98%	136560-76-4	1mg	$81	2024-03-01	Buy
Cayman Chemical	20064	N-Oleoyl Leucine ≥98%	136560-76-4	5mg	$317	2024-03-01	Buy
Cayman Chemical	20064	N-Oleoyl Leucine ≥98%	136560-76-4	10mg	$593	2024-03-01	Buy

Product number	Packaging	Price	Buy
20064	1mg	$81	Buy
20064	5mg	$317	Buy
20064	10mg	$593	Buy

N-Oleoyl Leucine Chemical Properties,Uses,Production

Description

N-Oleoyl leucine is an N-acyl amide generated by PM20D1 that uncouples mitochondrial respiration independent of uncoupling protein 1 (UCP1) in vitro.¹ N-Oleoyl leucine (25 mg/kg, i.p.) decreases body weight and food intake, preferentially decreasing fat mass in a diet-induced obesity mouse model. It improves glucose homeostasis in a fasting glucose tolerance test and increases VO₂ while slightly decreasing overall locomotor activity.

Definition

ChEBI: N-oleoyl-L-leucine is an L-leucine derivative resulting from the formal condensation of the carboxy group of oleic acid with the amino group of L-leucine. It is a L-leucine derivative and a N-(fatty acyl)-L-alpha-amino acid. It is functionally related to an oleic acid. It is a conjugate acid of a N-oleoyl-L-leucinate.

References

1. Long, J.Z., Svensson, K.J., Bateman, L.A., et al. The secreted enzyme PM20D1 regulates lipidated amino acid uncouplers of mitochondria Cell 166(2),1-12(2016).

N-Oleoyl Leucine Preparation Products And Raw materials

Raw materials

Preparation Products

N-Oleoyl Leucine Suppliers

Global( 8)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32070	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6777	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11217	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11974	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	19711	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
Shanghai Hongye Biotechnology Co. Ltd	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
Shanghai Yifei Biotechnology Co. , Ltd.	58
TargetMol Chemicals Inc.	58

View Lastest Price from N-Oleoyl Leucine manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-11-06	N-Oleoyl Leucine 136560-76-4	US $156.00-572.00 / mg		98.25%	10g	TargetMol Chemicals Inc.

N-Oleoyl Leucine
136560-76-4
US $156.00-572.00 / mg
98.25%
TargetMol Chemicals Inc.

N-Oleoyl Leucine NOleoyl Leucine,N Oleoyl Leucine L-Leucine, N-[(9Z)-1-oxo-9-octadecen-1-yl]- N-[(9Z)-1-oxo-9-octadecen-1-yl]-L-leucine 136560-76-4