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FM479

CAS No.
2226521-64-6
Chemical Name:
FM479
Synonyms
FM479;2-Cyano-3-(5-(1-cyclohexyl-6-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)furan-2-yl)-N,N-dimethylacrylamide;2-Propenamide, 2-cyano-3-[5-(1-cyclohexyl-1,6-dihydro-6-methylimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)-2-furanyl]-N,N-dimethyl-
CBNumber:
CB94667099
Molecular Formula:
C25H26N6O2
Molecular Weight:
442.51
MDL Number:
MFCD31697722
MOL File:
2226521-64-6.mol
Last updated:2023-07-12 16:44:02

FM479 Properties

Boiling point 735.7±70.0 °C(Predicted)
Density 1.33±0.1 g/cm3(Predicted)
pka 6.39±0.40(Predicted)

FM479 Chemical Properties,Uses,Production

Biological Activity

FM-479 is a negative control for FM-381 (HY-102046) and has no activity against JAK3 or other kinases. FM-381 is a potent covalent reversible inhibitor of JAK3 targeting unique Cys909.

in vitro

FM-479 is the inactive control of FM-381, the concentration used in assays is similar.

target

JAK3

FM479 Preparation Products And Raw materials

Raw materials

Preparation Products

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FM479 2-Propenamide, 2-cyano-3-[5-(1-cyclohexyl-1,6-dihydro-6-methylimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)-2-furanyl]-N,N-dimethyl- 2-Cyano-3-(5-(1-cyclohexyl-6-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)furan-2-yl)-N,N-dimethylacrylamide 2226521-64-6