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ChemicalBook >> CAS DataBase List >>N-{6-[(7S,9aS)-7-(hydroxymethyl)-octahydropyrazino[2,1-c][1,4]oxazin-8-yl]-4-(4-fluoro-2-methylphenyl)pyridin-3-yl}-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide

N-{6-[(7S,9aS)-7-(hydroxymethyl)-octahydropyrazino[2,1-c][1,4]oxazin-8-yl]-4-(4-fluoro-2-methylphenyl)pyridin-3-yl}-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide

N-{6-[(7S,9aS)-7-(hydroxymethyl)-octahydropyrazino[2,1-c][1,4]oxazin-8-yl]-4-(4-fluoro-2-methylphenyl)pyridin-3-yl}-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide Structure
N-{6-[(7S,9aS)-7-(hydroxymethyl)-octahydropyrazino[2,1-c][1,4]oxazin-8-yl]-4-(4-fluoro-2-methylphenyl)pyridin-3-yl}-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide structure
CAS No.
929046-33-3
Chemical Name:
N-{6-[(7S,9aS)-7-(hydroxymethyl)-octahydropyrazino[2,1-c][1,4]oxazin-8-yl]-4-(4-fluoro-2-methylphenyl)pyridin-3-yl}-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide
Synonyms
NT814;NT-814;NT 814;Elinzanetant;inhibit,BAY3427080,Elinzanetant,BAY-3427080,Inhibitor,Tachykinin receptor,NT-814,NT814,NK receptor,Neurokinin Receptor,NT 814,BAY 3427080;N-{6-[(7S,9aS)-7-(hydroxymethyl)-octahydropyrazino[2,1-c][1,4]oxazin-8-yl]-4-(4-fluoro-2-methylphenyl)pyridin-3-yl}-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide;2-[3,5-bis(trifluoromethyl)phenyl]-N-{4-(4-fluoro-2-methylphenyl)-6-[(7S,9aS)-7-(hydroxymethyl)hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl]pyridin-3-yl}-N,2-dimethylpropanamide;Benzeneacetamide, N-[4-(4-fluoro-2-methylphenyl)-6-[(7S,9aS)-hexahydro-7-(hydroxymethyl)pyrazino[2,1-c][1,4]oxazin-8(1H)-yl]-3-pyridinyl]-N,α,α-trimethyl-3,5-bis(trifluoromethyl)-
CBNumber:
CB94776711
Molecular Formula:
C33H35F7N4O3
Molecular Weight:
668.66
MDL Number:
MFCD34589885
MOL File:
929046-33-3.mol
Last updated:2024-07-26 15:15:01
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N-{6-[(7S,9aS)-7-(hydroxymethyl)-octahydropyrazino[2,1-c][1,4]oxazin-8-yl]-4-(4-fluoro-2-methylphenyl)pyridin-3-yl}-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide Properties

Boiling point 672.1±55.0 °C(Predicted)
Density 1.40±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 100 mg/mL (149.56 mM; Need ultrasonic)
pka 14.57±0.10(Predicted)
form Solid
color White to light yellow
InChIKey DWRIJNIPBUFCQS-NCTSPAQWNA-N
SMILES N(C1=CN=C(N2C[C@@]3([H])COCCN3C[C@H]2CO)C=C1C1C=CC(F)=CC=1C)(C)C(=O)C(C1C=C(C(F)(F)F)C=C(C(F)(F)F)C=1)(C)C |&1:7,15,r|
FDA UNII NZW2BOW35N

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501

N-{6-[(7S,9aS)-7-(hydroxymethyl)-octahydropyrazino[2,1-c][1,4]oxazin-8-yl]-4-(4-fluoro-2-methylphenyl)pyridin-3-yl}-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide Preparation Products And Raw materials

Raw materials

Preparation Products

N-{6-[(7S,9aS)-7-(hydroxymethyl)-octahydropyrazino[2,1-c][1,4]oxazin-8-yl]-4-(4-fluoro-2-methylphenyl)pyridin-3-yl}-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide Suppliers

Global( 37)Suppliers
Supplier Tel Email Country ProdList Advantage
Shijiazhuang Dingmin Pharmaceutical Sciences Co., Ltd.
+86-0311-67591193 +8613931880626 sales02@dingminpharma.com China 252 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38631 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52924 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		+8613720134139 orders@jknbiochem.com China 5221 58
Nanjing Vcare PharmaTech Co., Ltd 025-58741518 13327700685 sales@vcarepharmatech.com China 508 58
Taizhou Nanfeng Pharmaceutical Research Institute 18616377689 nanfengdrug@163.com China 20000 58
Bayee Biotech (Anqing) Co., Ltd. 0556-5032306 18917961636 wtx@bayeebio.com China 261 61
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. 17702719238 17702719238 sales@sun-shinechem.com China 985 64
Cangzhou Enke Pharma-tech Co., Ltd. 0317-5296180 15533709196 sale@enkepharma.com China 1931 55
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8012 62
Supplier Advantage
Shijiazhuang Dingmin Pharmaceutical Sciences Co., Ltd.
58
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		58
Nanjing Vcare PharmaTech Co., Ltd 58
Taizhou Nanfeng Pharmaceutical Research Institute 58
Bayee Biotech (Anqing) Co., Ltd. 61
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. 64
Cangzhou Enke Pharma-tech Co., Ltd. 55
ShangHai Biochempartner Co.,Ltd 62

N-{6-[(7S,9aS)-7-(hydroxymethyl)-octahydropyrazino[2,1-c][1,4]oxazin-8-yl]-4-(4-fluoro-2-methylphenyl)pyridin-3-yl}-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide Spectrum

N-{6-[(7S,9aS)-7-(hydroxymethyl)-octahydropyrazino[2,1-c][1,4]oxazin-8-yl]-4-(4-fluoro-2-methylphenyl)pyridin-3-yl}-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide(929046-33-3)1HNMR
N-{6-[(7S,9aS)-7-(hydroxymethyl)-octahydropyrazino[2,1-c][1,4]oxazin-8-yl]-4-(4-fluoro-2-methylphenyl)pyridin-3-yl}-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide Benzeneacetamide, N-[4-(4-fluoro-2-methylphenyl)-6-[(7S,9aS)-hexahydro-7-(hydroxymethyl)pyrazino[2,1-c][1,4]oxazin-8(1H)-yl]-3-pyridinyl]-N,α,α-trimethyl-3,5-bis(trifluoromethyl)- Elinzanetant NT 814 NT814 NT-814 2-[3,5-bis(trifluoromethyl)phenyl]-N-{4-(4-fluoro-2-methylphenyl)-6-[(7S,9aS)-7-(hydroxymethyl)hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl]pyridin-3-yl}-N,2-dimethylpropanamide inhibit,BAY3427080,Elinzanetant,BAY-3427080,Inhibitor,Tachykinin receptor,NT-814,NT814,NK receptor,Neurokinin Receptor,NT 814,BAY 3427080 929046-33-3 C33H35F7N4O3 API