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Asp-AMS

Asp-AMS structure

CAS No.: 828288-98-8

Chemical Name:: Asp-AMS

Synonyms: Asp-AMS;Asp AMS,AspAMS;Adenosine, 5'-[N-[(2S)-2-amino-3-carboxy-1-oxopropyl]sulfamate]

CBNumber:: CB94797022

Molecular Formula:: C14H19N7O9S

Molecular Weight:: 461.41

MDL Number:: MFCD31746899

MOL File:: 828288-98-8.mol

Last updated:2024-07-02 08:55:42

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Asp-AMS Properties

Density	2.14±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO : ≥ 100 mg/mL (216.73 mM)
form	Solid
pka	0.90±0.70(Predicted)
color	White to off-white

Asp-AMS price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0067151	Asp-AMS >98.0%	828288-98-8	5mg	$550	2021-12-16	Buy
ChemScene	CS-0067151	Asp-AMS >98.0%	828288-98-8	10mg	$850	2021-12-16	Buy
ChemScene	CS-0067151	Asp-AMS >98.0%	828288-98-8	25mg	$1750	2021-12-16	Buy
Biorbyt Ltd	orb573002	Asp-AMS >98%	828288-98-8	250mg	$3580.2	2021-12-16	Buy
Biorbyt Ltd	orb573002	Asp-AMS >98%	828288-98-8	1g	$7136.6	2021-12-16	Buy

Product number	Packaging	Price	Buy
CS-0067151	5mg	$550	Buy
CS-0067151	10mg	$850	Buy
CS-0067151	25mg	$1750	Buy
orb573002	250mg	$3580.2	Buy
orb573002	1g	$7136.6	Buy

Asp-AMS Chemical Properties,Uses,Production

Biological Activity

Asp-AMS is an analog of aspartate adenylate, an inhibitor of aspartyl-tRNA synthetase, and a potent and competitive inhibitor of mitochondrial enzyme.

in vitro

Asp-AMS is a 500-fold stronger competitive inhibitor of the mitochondrial enzyme than aspartol-AMP (10 nM) and a 35-fold lower competitor of human and bovine cyt-AspRSs (300 nM).It is a strong inhibitor with K _i in the nanomolar (nM) range.It has also the highest inhibitory effect for the mitochondrial enzyme.It is the most active inhibitor with K _i values in the nanomolar range, with a stronger effect on bacterial AspRSs ( E. coli and P. aeruginosa ) than on human cytosolic AspRS.

target

Aspartyl-tRNA synthetase, Mitochondrial enzyme .

Asp-AMS Preparation Products And Raw materials

Raw materials

Preparation Products

Asp-AMS Suppliers

Global( 11)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Fan De(Beijing) Biotechnology Co., Ltd.	15911056312	liming@bio-fount.com	China	9730	58
DC Chemicals	021-58447131 13564518121	sales@dcchemicals.com	China	9412	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Beijing Jin Ming Biotechnology Co., Ltd.	010-60605840 15801484223;	psaitong@jm-bio.com	China	29778	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24647	58
Shanghai Yiyan Biotechnology Co. , Ltd.	021-69985186 13611928337	3427709316@qq.com	China	7979	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11975	58
RD International Technology Co., Limited	18024082417	market@ubiochem.com	China	9268	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Fan De(Beijing) Biotechnology Co., Ltd.	58
DC Chemicals	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
Beijing Jin Ming Biotechnology Co., Ltd.	58
TargetMol Chemicals Inc.	58
Shanghai Yiyan Biotechnology Co. , Ltd.	58
Shanghai Yifei Biotechnology Co. , Ltd.	58
RD International Technology Co., Limited	58

Asp-AMS Adenosine, 5'-[N-[(2S)-2-amino-3-carboxy-1-oxopropyl]sulfamate] Asp AMS,AspAMS 828288-98-8 C14H19N7O9S