Dios-Arg (trifluoroacetate salt)
- CAS No.
- 1807353-31-6
- Chemical Name:
- Dios-Arg (trifluoroacetate salt)
- Synonyms
- Dios-Arg (trifluoroacetate salt);(3β,25R)-3-[6-[[(2S)-2-amino-5-[(aminoiminomethyl)amino]-1-oxopentyl]amino]hexanoate]spirost-5-en-3-ol,bis(2,2,2-trifluoroacetate)
- CBNumber:
- CB94814501
- Molecular Formula:
- C41H66F3N5O7
- Molecular Weight:
- 798
- MDL Number:
- MOL File:
- 1807353-31-6.mol
Dios-Arg (trifluoroacetate salt) price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 25945 | Dios-Arg (trifluoroacetate salt) | 1807353-31-6 | 5mg | $109 | 2024-03-01 | Buy |
| Cayman Chemical | 25945 | Dios-Arg (trifluoroacetate salt) | 1807353-31-6 | 10mg | $184 | 2024-03-01 | Buy |
| Cayman Chemical | 25945 | Dios-Arg (trifluoroacetate salt) | 1807353-31-6 | 1mg | $32 | 2024-03-01 | Buy |
| AK Scientific | 1546EN | [(4S)-4-Azaniumyl-5-oxo-5-[[6-oxo-6-[(1S,2S,4S,5'R,6R,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-yl]oxyhexyl]amino]pentyl]-(diaminomethylidene)azanium;2,2,2-trifluoroacetate | 1807353-31-6 | 10mg | $302 | 2021-12-16 | Buy |
Dios-Arg (trifluoroacetate salt) Chemical Properties,Uses,Production
Description
Dios-Arg is a steroid-based cationic lipid that contains a diosgenin skeleton coupled to an L-arginine head group.1 It forms a complex with plasmid DNA and decreases plasmid DNA migration in an agarose-gel retardant assay at charge ratio greater than or equal to 4.2 Dios-Arg facilitates transfection of plasmid DNA into H1299 and HeLa cells in the presence and absence of fetal bovine serum, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin and the caveolae-mediated endocytosis inhibitor genistein . It has been used, coupled to 1,2-dioleoyl-sn-glycero-3-PE (DOPE; ), to bind siRNA and plasmid DNA to for cationic lipid nanoparticles (LNPs) for intracellular transport. Dios-Arg is cytotoxic to H1299 and HeLa cells (IC50s = 83.5 and 74.1 μg/ml, respectively).2
References
1. Sheng, R., Zhuang, X., Wang, Z., et al. Cationic nanoparticles assembled from natural-
2. Sheng, R., Wang, Z., Luo, T., et al. Skeleton-
Dios-Arg (trifluoroacetate salt) Preparation Products And Raw materials
Raw materials
Preparation Products
Dios-Arg (trifluoroacetate salt) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6777 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24644 | 58 |
| Shanghai Easy CDMO Co.,Ltd | 021-61734564 | August@easycdmo.com | China | 10030 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11974 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | ET-market@chemextension.com | China | 25929 | 58 |
View Lastest Price from Dios-Arg (trifluoroacetate salt) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-24 | Dios-Arg (trifluoroacetate salt)
1807353-31-6
|
US $273.00-78.00 / mg | 10g | TargetMol Chemicals Inc. |
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- Dios-Arg (trifluoroacetate salt)
1807353-31-6
- US $273.00-78.00 / mg
- TargetMol Chemicals Inc.