Fluorinated VHL spy molecule 1
- CAS No.
- 2290526-08-6
- Chemical Name:
- Fluorinated VHL spy molecule 1
- Synonyms
- Fluorinated VHL spy molecule 1;(2S,4R)-1-(3,3-dimethylbutanoyl)-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)-3-(trifluoromethyl)phenyl]methyl}pyrrolidine-2-carboxamide;2-Pyrrolidinecarboxamide, 1-(3,3-dimethyl-1-oxobutyl)-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)-3-(trifluoromethyl)phenyl]methyl]-, (2S,4R)-
- CBNumber:
- CB95541855
- Molecular Formula:
- C23H28F3N3O3S
- Molecular Weight:
- 483.55
- MDL Number:
- MOL File:
- 2290526-08-6.mol
Fluorinated VHL spy molecule 1 price More Price(2)
Fluorinated VHL spy molecule 1 Chemical Properties,Uses,Production
Uses
Fluorinated VHL Spy Molecule 1 can be used for the discovery of new von Hippel-Lindau (VHL) binders. Based on VH032 (cat# 901490), this reporter was designed in the lab of Alessio Ciulli to bind the hydroxyproline (Hyp) recognition site of VHL. When used in competition ligand-observed 19F NMR screening experiments, its displacement indicates binding by another molecule. Additional Fluorinated VHL Spy Molecules are available as listings 909432, 909440 and 909459.
The E3 ligase VHL is of growing interest for targeted protein degradation, and these spy molecules will facilitate the identification of novel VHL ligands and VHL-based degraders.
Fluorinated VHL spy molecule 1 Preparation Products And Raw materials
Raw materials
Preparation Products
Fluorinated VHL spy molecule 1 Suppliers
Global( 6)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | info@SuperLan-chem.com | China | 9949 | 58 |
| Jilin Province Woda Biotechnology Co., Ltd. | 13504435624 | 1927928688@qq.com | China | 1385 | 58 |
| Changzhou Bojia Biomedical Technology Co., Ltd. | 2122619822 | czbjpharma@126.com | China | 18488 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 13417589054 | trendseenbio@gmail.com | China | 9880 | 58 |
| Elucigen bio | 13501719342 | wayne.zheng@elucigenbio.com | China | 4587 | 58 |
Fluorinated VHL spy molecule 1
2-Pyrrolidinecarboxamide, 1-(3,3-dimethyl-1-oxobutyl)-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)-3-(trifluoromethyl)phenyl]methyl]-, (2S,4R)-
(2S,4R)-1-(3,3-dimethylbutanoyl)-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)-3-(trifluoromethyl)phenyl]methyl}pyrrolidine-2-carboxamide
2290526-08-6