MK-0736
- CAS No.
- 719272-79-4
- Chemical Name:
- MK-0736
- Synonyms
- MK-0736;4H-1,2,4-Triazole, 3-[4-[3-(ethylsulfonyl)propyl]bicyclo[2.2.2]oct-1-yl]-4-methyl-5-[2-(trifluoromethyl)phenyl]-
- CBNumber:
- CB95852726
- Molecular Formula:
- C23H30F3N3O2S
- Molecular Weight:
- 469.56
- MDL Number:
- MOL File:
- 719272-79-4.mol
| FDA UNII | 9RT16RBU2Y |
|---|
MK-0736 Chemical Properties,Uses,Production
Uses
MK-0736 is a 11β-HSD type 1 (11β-HSD1) inhibitor that reduces blood pressure. MK-0736 can be used for type 2 diabetes and metabolic syndrome research[1].
References
[1] Sukrut Shah, et al. Efficacy and safety of the selective 11β-HSD-1 inhibitors MK-0736 and MK-0916 in overweight and obese patients with hypertension. J Am Soc Hypertens. 2011 May-Jun;5(3):166-76. DOI:10.1016/j.jash.2011.01.009
[2] Bauman DR, et al. Evaluation of selective inhibitors of 11β-HSD1 for the treatment of hypertension. Bioorg Med Chem Lett. 2013 Jun 15;23(12):3650-3. DOI:10.1016/j.bmcl.2013.03.011
MK-0736 Preparation Products And Raw materials
Raw materials
Preparation Products
MK-0736 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32202 | 58 |
| TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19889 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19746 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
