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Dolutegravir Impurity C

Dolutegravir Impurity C structure

CAS No.: 1802141-49-6

Chemical Name:: Dolutegravir Impurity C

Synonyms: Dolutegravir Impurity 20;Dolutegravir Impurity 23;Dolutegravir Impurity 32;Syringaresinol Impurity 1(Syringaresinol Diglucoside);(4R,12aS)-N-(2,4-difluorobenzyl)-7-ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1,2:;(4R,12aS)-N-(2,4-difluorobenzyl)-7-ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1'',2'':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,4-difluorophenyl)methyl]-7-ethoxy-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo-, (4R,12aS)-

CBNumber:: CB96222324

Molecular Formula:: C22H23F2N3O5

Molecular Weight:: 447.43

MDL Number:

MOL File:: 1802141-49-6.mol

Last updated:2022-12-21 16:56:50

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Dolutegravir Impurity C Properties

Boiling point	688.1±55.0 °C(Predicted)
Density	1.42±0.1 g/cm3(Predicted)
pka	10.71±0.40(Predicted)
FDA UNII	674Y3KR4XU

Dolutegravir Impurity C Chemical Properties,Uses,Production

Uses

O-Ethyl Dolutegravir is an impurity of Dolutegravir (D528800), which is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.

Dolutegravir Impurity C Preparation Products And Raw materials

Raw materials

Preparation Products

Dolutegravir Impurity C Suppliers

Global( 9)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd.	020-89854820	sales@jzpharma.cn	China	1050	58
Shenzhen Hengfeng Wanda Pharmaceutical Technology Co., Ltd	0755-22677922 18126518403	2851922760@qq.com	China	5043	58
Molcoo Chemicals Inc.	18627923403 18627753421	3001006472@qq.com	China	9022	58
Shenzhen Roark Pharma-Tec Co., Ltd.	13128912434	2880126944@qq.com	China	2579	58
guoyungurui	18162595016	3287908757@qq.com	China	10012	58
ShenZhen H&D Pharmaceutical Technology Co., LTD	18367470722	2885785763@qq.com	China	3763	58

Supplier	Advantage
Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd.	58
Shenzhen Hengfeng Wanda Pharmaceutical Technology Co., Ltd	58
Molcoo Chemicals Inc.	58
Shenzhen Roark Pharma-Tec Co., Ltd.	58
guoyungurui	58
ShenZhen H&D Pharmaceutical Technology Co., LTD	58

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Dolutegravir Impurity 24

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Dolutegravir Impurity 20 (4R,12aS)-N-(2,4-difluorobenzyl)-7-ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1,2: Dolutegravir Impurity 23 (4R,12aS)-N-(2,4-difluorobenzyl)-7-ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1'',2'':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide 2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,4-difluorophenyl)methyl]-7-ethoxy-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo-, (4R,12aS)- Dolutegravir Impurity 32 Syringaresinol Impurity 1(Syringaresinol Diglucoside) 1802141-49-6