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N-(4-BROMOPHENYL)MORPHOLINE

CAS No.
30483-75-1
Chemical Name:
N-(4-BROMOPHENYL)MORPHOLINE
Synonyms
N-(4-BROMOPHENYL)MORPHOLINE;1-Bromo-4-morpholinobenzene;4-(4'-BROMOPHENYL)MORPHOLINE;Morpholine,4-(4-bromophenyl)-;4-(4-Bromophenyl)morpholine 97%
CBNumber:
CB9697164
Molecular Formula:
C10H12BrNO
Molecular Weight:
242.11
MDL Number:
MFCD04112483
MOL File:
30483-75-1.mol
MSDS File:
SDS
Last updated:2023-06-08 17:06:38

N-(4-BROMOPHENYL)MORPHOLINE Properties

Melting point 114-118 °C (lit.)
Boiling point 341.2±37.0 °C(Predicted)
Density 1.433±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
form powder to crystal
pka 4.33±0.40(Predicted)
color White to Light yellow to Light orange

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
HS Code  2934999090
NFPA 704
0
2 0

N-(4-BROMOPHENYL)MORPHOLINE price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 591777 4-(4-Bromophenyl)morpholine 97% 30483-75-1 5g $58.8 2024-03-01 Buy
Sigma-Aldrich 591777 4-(4-Bromophenyl)morpholine 97% 30483-75-1 25g $259 2024-03-01 Buy
TCI Chemical B4890 4-(4-Bromophenyl)morpholine >98.0%(GC)(T) 30483-75-1 5g $129 2024-03-01 Buy
TCI Chemical B4890 4-(4-Bromophenyl)morpholine >98.0%(GC)(T) 30483-75-1 25g $381 2023-01-07 Buy
TRC B678033 4-(4-Bromophenyl)morpholine 30483-75-1 500mg $75 2021-12-16 Buy
Product number Packaging Price Buy
591777 5g $58.8 Buy
591777 25g $259 Buy
B4890 5g $129 Buy
B4890 25g $381 Buy
B678033 500mg $75 Buy

N-(4-BROMOPHENYL)MORPHOLINE Chemical Properties,Uses,Production

Uses

N-(4-BROMOPHENYL)MORPHOLINE is used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Synthesis

1.jpg
In an open flask, 10 mL of 1.5 M NaBr in pH 6.2 phosphate buffer (0.23 M in PO4) or pH 4.2 phosphate buffer (5% NaH2PO4) was added to a solution of 1 mmol of substrate dissolved in 9.75 mL of distilled 1,4- dioxane. To this mixture was added a freshly made solution of diphenyl ditelluride (1e, 0.25 mL of a 10 mM stock in 1,4-dioxane, 2.5 μmol, 0.25 mol % relative to substrate) followed by the addition of 8.8 M H2O2 according to Table 3. The reaction mixture was stirred at room temperature for the appropriate amount of time and was then diluted with 10 mL of water. The resulting solution was extracted with EtOAc (3 × 10 mL), and the combined organic extracts were washed with 0.5 M NaHSO3 (5 mL) and brine (10 mL), dried over MgSO4, and concentrated. Yields reported below are the mean of duplicate runs. N-(4-Bromophenyl)morpholine (21):28 product isolated as a tan solid (224 ± 1 mg, 93% yield). Mp 111-113 °C (lit.28 mp 111-112 °C).

N-(4-BROMOPHENYL)MORPHOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(4-BROMOPHENYL)MORPHOLINE 4-(4'-BROMOPHENYL)MORPHOLINE 1-Bromo-4-morpholinobenzene 4-(4-Bromophenyl)morpholine 97% Morpholine,4-(4-bromophenyl)- 30483-75-1 Building Blocks Heterocyclic Building Blocks Halogenated Heterocycles Morpholines Building Blocks Chemical Synthesis Halogenated Heterocycles Heterocyclic Building Blocks Morpholines/Thiomorpholines pharmacetical Miscellaneous