ChemicalBook >> CAS DataBase List >>Boc-Dap-OH
Boc-Dap-OH
- CAS No.
- 73259-81-1
- Chemical Name:
- Boc-Dap-OH
- Synonyms
- BOC-L-DAP-OH;(S)-3-AMINO-2-(TERT-BUTOXYCARBONYLAMINO)PROPANOIC ACID;BOC-L-DAP;BOC-DPR-OH;BOC-DAP-OH;Boc-Dapa-OH;BOC-L-DAPA-OH;(N-Boc-β-amino)-AL;Boc-Dap-OH USP/EP/BP;3-Amino-Boc-L-alanin
- CBNumber:
- CB9715251
- Molecular Formula:
- C8H16N2O4
- Molecular Weight:
- 204.22
- MDL Number:
- MFCD00236843
- MOL File:
- 73259-81-1.mol
- MSDS File:
- SDS
Last updated:2023-10-25 11:55:14
| Melting point | 210 °C (dec.) |
|---|---|
| alpha | -5.5 º (c=1, acetic acid) |
| Boiling point | 364.4±37.0 °C(Predicted) |
| Density | 1.189±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | DMSO (Slightly, Heated, Sonicated), Water (Sparingly, Heated, Sonicated) |
| form | Solid |
| pka | 2.88±0.16(Predicted) |
| color | White to Off-White |
| optical activity | [α]20/D +5.5±1°, c = 1% in methanol: water (1:1) |
| BRN | 4182136 |
| InChI | InChI=1S/C8H16N2O4/c1-8(2,3)14-7(13)10-5(4-9)6(11)12/h5H,4,9H2,1-3H3,(H,10,13)(H,11,12)/t5-/m0/s1 |
| InChIKey | KRJLRVZLNABMAT-YFKPBYRVSA-N |
| SMILES | C(O)(=O)[C@H](CN)NC(OC(C)(C)C)=O |
| CAS DataBase Reference | 73259-81-1(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |     GHS05,GHS07,GHS08,GHS02 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H314-H361-H335-H336-H225-H260 | |||||||||
| Precautionary statements | P501-P223-P261-P270-P202-P240-P231+P232-P210-P233-P201-P243-P241-P242-P271-P264-P280-P370+P378-P335+P334-P308+P313-P303+P361+P353-P301+P330+P331-P363-P301+P312+P330-P304+P340+P310-P305+P351+P338+P310-P403+P233-P402+P404-P403+P235-P405 | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29241990 | |||||||||
| NFPA 704 |
|
Boc-Dap-OH price More Price(52)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 15402 | Boc-Dap-OH ≥98.0% (TLC) | 73259-81-1 | 1g | $86.8 | 2024-03-01 | Buy |
| Sigma-Aldrich | 15402 | Boc-Dap-OH ≥98.0% (TLC) | 73259-81-1 | 5g | $390 | 2024-03-01 | Buy |
| TCI Chemical | A2470 | (S)-3-Amino-2-(tert-butoxycarbonylamino)propionic Acid >95.0%(HPLC)(T) | 73259-81-1 | 1g | $25 | 2024-03-01 | Buy |
| TCI Chemical | A2470 | (S)-3-Amino-2-(tert-butoxycarbonylamino)propionic Acid >95.0%(HPLC)(T) | 73259-81-1 | 5g | $72 | 2024-03-01 | Buy |
| Alfa Aesar | H26919 | N(alpha)-Boc-L-2,3-diaminopropionic acid, 97% | 73259-81-1 | 1g | $63.65 | 2024-03-01 | Buy |
Boc-Dap-OH Chemical Properties,Uses,Production
Chemical Properties
White powder
Uses
Reactant for:
- Protein assembly directed by synthetic molecular recognition motifs
- Solid phase synthesis of gramicidin S cyclic analogs with antibiotic and hemolytic activities
- Synthesis of HCV protease inhibitor modified analogs
- Solid phase synthesis of peptidic V1a receptor agonists
- Directed peptide assembly at lipid-water interface
Uses
(S)-3-amino-2-(tert-Butoxycarbonylamino)propionic acid (Boc-Dap-OH) is a derivative of amino acids, mainly used as an intermediate in organic synthesis and pharmaceutical chemistry, and can be used in the synthesis of peptide drug molecules and bioactive molecules.
Preparation
The raw material was dissolved inabsolute ethanol (5 mL), and the reaction flask was immersed in a water bath at 25 C. To the alcoholicsolution, 10% palladium-carbon (22.9 mg) and 1,4-cyclohexadiene (10 equivalents with respect to4; 0.47 mL, 5.0 mmol) were added, and the mixture was allowed to react under magnetic stirringovernight. After filtration over a short pad of Celite 545, the solvent was evaporated under reducedpressure conditions, and the solid residue was partitioned in a 1:1 (v/v) H2O/EtOAc mixture (10 mL).The aqueous phase was separated, back extracted with EtOAc (3 10 mL), concentrated under reducedpressure conditions, and lyophilized.Finally, the target product Boc-Dap-OH is obtained.
Definition
Boc-Dap-OH is an amino acid molecule that is a zwitterion. Therefore, the addition of a base is required to prepare a nucleophilic amino acid. It is commonly acts as a nucleophile to attack the acyl carbon.
Boc-Dap-OH Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 243)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sichuan HongRi Pharma-Tech Co.,Ltd | +86-028-64841719 +8617390183901 | daisy@enlaibio.com | China | 1106 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29882 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Sichuan Jiaying Lai Technology Co.,LTD | 18716376478 | ycling@enlaibio.com | CHINA | 302 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8838 | 58 |
View Lastest Price from Boc-Dap-OH manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-22 | Boc-L-Dap-OH
73259-81-1
|
US $0.00-0.00 / kg | 1kg | 98% | 1T+ | Sichuan HongRi Pharma-Tech Co.,Ltd | |
 |
2020-01-06 | Boc-Dap-OH
73259-81-1
|
US $1.00 / g | 1g | 98% | 100KG | Sichuan Jiaying Lai Technology Co.,LTD | |
|
|
2020-01-06 | Boc-Dap-OH
73259-81-1
|
US $1.00 / g | 1g | 98% | 100KG | Sichuan Jiaying Lai Technology Co.,LTD |
-
- Boc-L-Dap-OH
73259-81-1
- US $0.00-0.00 / kg
- 98%
- Sichuan HongRi Pharma-Tech Co.,Ltd
-
- Boc-Dap-OH
73259-81-1
- US $1.00 / g
- 98%
- Sichuan Jiaying Lai Technology Co.,LTD
-
- Boc-Dap-OH
73259-81-1
- US $1.00 / g
- 98%
- Sichuan Jiaying Lai Technology Co.,LTD
73259-81-1(Boc-Dap-OH)Related Search:
Cbz-beta-Amino-L-alanine
(S)-1-N-BOC-4-N-FMOC-PIPERAZINE-2-CARBOXYLIC ACID
(S)-N-1-Boc-N-4-Cbz-2-piperazine carboxylic acid
(S)-4-Boc-Piperazine-3-carboxylic acid
Boc-Dap-OH
1of4
Nalpha-BOC-beta-Amino-L-alanine,97%
(s)-3-Amino-2-tert-butoxycarbonylamino-propionic acid
3-Amino-2-tert-butoxycarbonylamino-propionic acid
Boc-Dapa-OH
3-AMINO-(TERT-BUTOXYCARBONYL)-L-ALANINE
Nα-Boc-L-2,3-diaminopropionic acid≥ 98% (HPLC)
L-ALANINE, 3-AMINO-N-[(1,1-DIMETHYLETHOXY)CARBONYL]-
BOC-L-DAPA-OH
BOC-L-2,3-DIAMINOPROPIONIC ACID
BOC-L-ALPHA,BETA-DIAMINOPROPIONIC ACID
BOC-DPR-OH
BOC-DAP-OH
BOC-ALPHA,BETA-DIAMINOPROPIONIC ACID
T-BUTYLOXYCARBONYL-L-2,3-DIAMINOPROPIONIC ACID
N-ALPHA-BOC-(S)-2,3-DIAMINOPROPIONIC ACID
NALPHA-BOC-L-BETA-AMINOALANINE
N-ALPHA-BOC-L-DIAMINOPROPIONIC ACID
N-ALPHA-BOC-L-2,3-DIAMINOPROPIONIC ACID
N-ALPHA-BOC-BETA-AMINO-L-ALANINE
Boc-Dap-OH(Na-Boc-2,3-DiaMinopropionic acid)
3-[(tert-butoxy)(carbaMoyl)aMino]propanoic acid
Nalpha-BOC-beta-AMino-L-alanine, 97% 1GR
Nalpha-Boc-2,3-diaminopropionic Acid
3-Amino-N-(tert-butoxycarbonyl)-L-alanine
3-Amino-N-Boc-L-alanine
Boc-Dap-OH
Boc-Dpr-OH
(S)-3-AMino-2-Boc-propionic acid
N2-tertbutoxycarbonyl-L-2,3-diaMinopropanoic acid
(S)-3-AMino-2-Boc-propionic acid
3-Amino-N-(tert-butoxycarbonyl)-L-alanine
(S)-2-(AMinoMethyl)-4-(tert-butoxy)-4-oxobutanoic acid
(S)-2-[(tert-Butoxycarbonyl)amino]-3-aminopropionic acid
N2-(tert-Butoxycarbonyl)-(S)-2,3-diaminopropionic acid
N2-tert-Butoxycarbonyl-L-2,3-diaminopropionic acid
Nα-BOC-(S)-β-aminoalanine
Nα-Boc-L-β-aminoalanine
(S)-3-AMino-Boc-Alanine
N-ALPHA-T-BUTOXYCARBONYL-L-ALPHA,BETA-DIAMINOPROPIONIC ACID
N-ALPHA-L-(BUTOXYCARBONYL)2,3-DIAMINOPROPIONIC ACID
N-ALPHA-TERT-BUTYLOXYCARBONYL-L-2,3-DIAMINOPROPIONIC ACID
(N-BOC-BETA-AMINO)-ALA-OH
N-T-BOC-BETA-AMINO-L-ALANINE
Boc-Dpr-OH, N-Boc-L-2,3-diaminopropanoic acid
Na-Boc-L-2,3-diaminopropionic acid
N-t-BOC-?amino-L-alanine
N-BOC-L-2,3-DIAMINOPROPANOIC ACID
(n-boc-β-amino)-ala-oh
BOC-L-DAP-OH BOC-L-2,3- DIAMINOPROPIONIC ACID
N-ALPHA-T-BUTYLOXYCARBONYL-L-2,3-DIAMINOPROPIONIC ACID
NALPHA-tert-Butoxycarbonyl-L-2,3-diaminopropionic acid
N-ALPHA-L-(BUTOXYCARBONYL)-2,3-DIAMINOPROPIONIC
N-TERT-BOC-BETA-AMINO-L-ALANINE
3-Amino-Boc-L-alanine
N(ɑ)-Boc-L-2,3-diaminopropionic acid, 97%
3-Amino-(tert-butoxycarbonyl)-L-alanine, Boc-Dap-OH, Boc-Dpr-OH, (S)-3-Amino-2-(tert-butoxycarbonylamino)propanoic acid, Nα-Boc-L-2,3-diaminopropionic acid
3-Amino-(tert-butoxycarbonyl)-L-alanine, Boc-Dpr-OH, (S)-3-Amino-2-(tert-butoxycarbonylamino)propanoic acid, Nα-Boc-L-2,3-diaminopropionic acid
(S)-3-Amino-2-(tert-butoxycarbonylamino)propionic Acid >
(N-Boc-β-amino)-AL
N(Alpha)-Boc-L-2,3-DiaminopropionicAci
Boc-Dap-OH USP/EP/BP
Nα-Boc-L-2,3-diaminopropionic acid