2-Chlorobenzoyl chloride
- CAS No.
- 609-65-4
- Chemical Name:
- 2-Chlorobenzoyl chloride
- Synonyms
- O-CHLOROBENZOYL CHLORIDE;OCOC;o-ChL;SKL750;orobenzoyL;o-Chlorobenzoylchlor;chlorobenzoylchloride;o-Chlorbenzoylchlorid;o-Chlorobenzoylchlorid;LABOTEST-BB LTBB000568
- CBNumber:
- CB9721544
- Molecular Formula:
- C7H4Cl2O
- Molecular Weight:
- 175.01
- MDL Number:
- MFCD00000660
- MOL File:
- 609-65-4.mol
- MSDS File:
- SDS
| Melting point | -4--3 °C (lit.) |
|---|---|
| Boiling point | 238 °C (lit.) |
| Density | 1.382 g/mL at 25 °C (lit.) |
| vapor pressure | 0.1 hPa (20 °C) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Store below +30°C. |
| form | Liquid |
| color | Clear colorless to very slightly yellow |
| explosive limit | 1.5-9.4%(V) |
| Water Solubility | Soluble in acetone, ether, and alcohol. Solubility in water it decomposes. |
| Sensitive | Moisture Sensitive |
| BRN | 386435 |
| CAS DataBase Reference | 609-65-4(CAS DataBase Reference) |
| FDA UNII | JR29A4N74X |
| NIST Chemistry Reference | Benzoyl chloride, 2-chloro-(609-65-4) |
| EPA Substance Registry System | Benzoyl chloride, 2-chloro- (609-65-4) |
| UNSPSC Code | 12352106 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314 | |||||||||
| Precautionary statements | P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405 | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 34 | |||||||||
| Safety Statements | 26-36/37/39-45-28A | |||||||||
| RIDADR | UN 3265 8/PG 2 | |||||||||
| WGK Germany | 1 | |||||||||
| F | 19-21 | |||||||||
| Autoignition Temperature | 600 °C | |||||||||
| Hazard Note | Corrosive/Moisture Sensitive | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29163900 | |||||||||
| Toxicity | LD50 orally in Rabbit: 3250 mg/kg | |||||||||
| NFPA 704 |
|
2-Chlorobenzoyl chloride price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 103918 | 2-Chlorobenzoyl chloride 95% | 609-65-4 | 5g | $55.8 | 2024-03-01 | Buy |
| Sigma-Aldrich | 103918 | 2-Chlorobenzoyl chloride 95% | 609-65-4 | 100g | $107 | 2024-03-01 | Buy |
| Sigma-Aldrich | 8.21989 | 2-Chlorobenzoyl chloride for synthesis | 609-65-4 | 250ML | $51.3 | 2024-03-01 | Buy |
| TCI Chemical | C0140 | 2-Chlorobenzoyl Chloride >98.0%(GC)(T) | 609-65-4 | 25mL | $24 | 2024-03-01 | Buy |
| TCI Chemical | C0140 | 2-Chlorobenzoyl Chloride >98.0%(GC)(T) | 609-65-4 | 100mL | $37 | 2024-03-01 | Buy |
2-Chlorobenzoyl chloride Chemical Properties,Uses,Production
Chemical Properties
clear colourless to very slightly yellow liquid
Uses
2-Chlorobenzoyl chloride, is used in organic synthesis. It is used as a pharmaceutical intermediate for eg as an intermediate of clotrimazolc, preparation of p-chlorobenzoic acid and production of trichloro-acaricide.
Definition
ChEBI: An acyl chloride consisting of benzoyl chloride having a chloro substituent in the ortho-position.
General Description
2-Chlorobenzoyl chloride reacts with aromatic amines and ammonium thiocyanate using polyethylene glycol-400 as the catalyst under the condition of solid-liquid phase-transfer catalysis to form N-aryl-N′(2-chlorobenzoyl) thioureas. 2-Chlorobenzoyl chloride causes the acylation of polystyrene during the preparation and regeneration of the polystyrene-based resin.
Synthesis
A process for preparing 2-chlorobenzoyl chloride which comprises reacting 2-chlorobenzaldehyde with chlorine in the presence of phosphorus pentachloride at a temperature of from 50° to 200° C. and wherein the 2-chlorobenzaldehyde: phosphorus pentachloride ratio is from 1:0.05 to 1:0.2. Phosphorus pentachloride (41.5 g, 0.2 mole) was added to 2-chlorobenzaldehyde (289.7 g, 2.0 mole, 97%). After the ensuing exotherm had subsided, the resulting red solution was heated to 160° C. A stream of chlorine was introduced through a sparge tube into the solution for six hours. (Gas chromatography indicated 96.5% conversion.) The solution was then cooled and distilled under reduced pressure, giving 325.4 grams of 2-chlorobenzoyl chloride, which boiled at 135° to 140° C. at 16 millimeters of mercury. The yield of 2-Chlorobenzoyl chloride was 93% (98.5% pure).
2-Chlorobenzoyl chloride Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1of3
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8804 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5887 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18949 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21632 | 55 |
| Shanxi Naipu Import and Export Co.,Ltd | +86-13734021967 +8613734021967 | kaia@neputrading.com | China | 1001 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8618959220845 | sales@amoychem.com | China | 6383 | 58 |
| HubeiwidelychemicaltechnologyCo.,Ltd | 18627774460 | faith@widelychemical.com | CHINA | 742 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Shanghai Longyu Biotechnology Co., Ltd. | +8619521488211 | info@longyupharma.com | China | 2558 | 58 |
View Lastest Price from 2-Chlorobenzoyl chloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-02-14 | 2-Chlorobenzoyl Chloride
609-65-4
|
US $10.00 / Kg/Bag | 25Kg/Bag | 99.99% | 100ton | Hebei Mujin Biotechnology Co.,Ltd | |
 |
2024-11-01 | 2-Chlorobenzoyl chloride
609-65-4
|
US $1.00 / KG | 1KG | 99% | 10 mt | Hebei Weibang Biotechnology Co., Ltd | |
 |
2024-10-11 | Chlorobenzoyl Chlorid Orobenzoyl
609-65-4
|
US $19.00 / KG | 1KG | 99.% | 10 ton | Hebei Chuanghai Biotechnology Co,.LTD |
-
- 2-Chlorobenzoyl Chloride
609-65-4
- US $10.00 / Kg/Bag
- 99.99%
- Hebei Mujin Biotechnology Co.,Ltd
-
- 2-Chlorobenzoyl chloride
609-65-4
- US $1.00 / KG
- 99%
- Hebei Weibang Biotechnology Co., Ltd
-
- Chlorobenzoyl Chlorid Orobenzoyl
609-65-4
- US $19.00 / KG
- 99.%
- Hebei Chuanghai Biotechnology Co,.LTD