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9-L-Leucine-1-9-kallidin

CAS No.
71800-37-8
Chemical Name:
9-L-Leucine-1-9-kallidin
Synonyms
9-L-Leucine-1-9-kallidin;(DES-ARG10,LEU9)-KALLIDIN;1-9-Kallidin, 9-L-leucine-;LYS-(DES-ARG9,LEU8)-BRADYKININ;Lys-(Des-Arg?,Leu?)-Bradykinin;[LYS0, DES-ARG9, LEU8]BRADYKININ;LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-LEU;H-LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-LEU-OH;LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-LEU: KRPPGFSPL;Lys-(Des-Arg9,Leu8)-Bradykinin (Des-Arg10,Leu9)-Kallidin
CBNumber:
CB9723689
Molecular Formula:
C47H75N13O11
Molecular Weight:
998.2
MDL Number:
MFCD00274007
MOL File:
71800-37-8.mol
MSDS File:
SDS
Last updated:2024-07-02 08:55:42

9-L-Leucine-1-9-kallidin Properties

Density 1.45±0.1 g/cm3(Predicted)
storage temp. −20°C
pka 3.71±0.21(Predicted)
form Solid
color White to off-white

SAFETY

Risk and Safety Statements

WGK Germany  3

9-L-Leucine-1-9-kallidin price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Alfa Aesar J66538 Lys-[Des-Arg9, Leu8]-Bradykinin 71800-37-8 5mg $184 2021-12-16 Buy
Biorbyt Ltd orb372521 Lys-(Des-Arg9, Leu8)-Bradykinin > 95% 71800-37-8 1mg $287.3 2021-12-16 Buy
Biorbyt Ltd orb372521 Lys-(Des-Arg9, Leu8)-Bradykinin > 95% 71800-37-8 5mg $552.5 2021-12-16 Buy
Biorbyt Ltd orb372521 Lys-(Des-Arg9, Leu8)-Bradykinin > 95% 71800-37-8 10mg $708.9 2021-12-16 Buy
American Custom Chemicals Corporation SHG0000145 LYS-(DES-ARG9, LEU8)-BRADYKININ TRIFLUOROACETATE SALT 95.00% 71800-37-8 25MG $840.44 2021-12-16 Buy
Product number Packaging Price Buy
J66538 5mg $184 Buy
orb372521 1mg $287.3 Buy
orb372521 5mg $552.5 Buy
orb372521 10mg $708.9 Buy
SHG0000145 25MG $840.44 Buy

9-L-Leucine-1-9-kallidin Chemical Properties,Uses,Production

Description

Lys-(des-Arg9, Leu8)-Bradykinin trifluoroacetate salt is a peptide chain containing nine amino acids. The amino acid sequence of bradykinin is Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg (RPPGFSPFR). Bradykinin is a peptide that causes blood vessels to dilate, thus resulting in lower blood pressure. A class of drugs used to lower blood pressure called ACE inhibitors lower blood pressure by increasing the concentration of bradykinin (by inhibiting its degradation). Bradykinin acts on blood vessels by releasing prostacyclin, nitric oxide, and endothelial-derived hyperpolarizing factors.

Application

As one of the end effectors of the kallikrein-kinin system,Lys-(des-Arg9, Leu8)-Bradykinin trifluoroacetate salt has various biological activities, such as vasodilator, increase vascular permeability, induce contraction of non-vascular smooth muscle and so on.

Mechanism of action

Lys-(des-Arg9, Leu8)-Bradykinin trifluoroacetate salt is a potent endothelium-dependent vasodilator that causes non-vascular smooth muscle contraction, increases vascular permeability and is also involved in pain mechanisms. Bradykinin also causes an increase in urine sodium, which helps lower blood pressure.

It increases calcium levels inside neocortical astrocytes, causing them to release glutamate.

In some patients treated with angiotensin I-converting enzyme (ACE) inhibitors, bradykinin has been implicated as a cause of dry cough. This difficult-to-treat cough usually results from discontinuation of ACE inhibitor therapy. In such cases, angiotensin II receptor antagonists are used as the next step in therapy.

9-L-Leucine-1-9-kallidin Preparation Products And Raw materials

Raw materials

Preparation Products

9-L-Leucine-1-9-kallidin Suppliers

Global( 72)Suppliers
Supplier Tel Email Country ProdList Advantage
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715 admin@nexconn.com China 10311 58
Cellmano Biotech Limited
0551-65326643 18156095617 info@cellmano.com China 999 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29811 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10473 58
Hangzhou Go Top Peptide Biotech
0571-88211921 sales1@gotopbio.com CHINA 2609 58
Chengdu Youngshe Chemical Co., Ltd.
+8618108235634 Cecilia@youngshechem.com China 2345 58
Nanjing Doge Biomedical Technology Co., Ltd
+86-25-58227606 +86-15305155328 sales@dogechemical.com China 4128 58
Nanjing TGpeptide
+86-13347807150 +86-13347807150 support@tgpeptide.com China 3279 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43340 58
Changsha MOL Changes Biotechnology Co., Ltd.
+8619375158599 info@molchanges.com China 5223 58

View Lastest Price from 9-L-Leucine-1-9-kallidin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
	(DES-ARG10,LEU9)-KALLIDIN pictures 2020-02-19 (DES-ARG10,LEU9)-KALLIDIN
71800-37-8
US $7.00 / KG 1KG 99% 100kg Career Henan Chemical Co
(DES-ARG10,LEU9)-KALLIDIN H-LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-LEU-OH LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-LEU LYS-(DES-ARG9,LEU8)-BRADYKININ [LYS0, DES-ARG9, LEU8]BRADYKININ Lys-(des-Arg9, Leu8)-Bradykinin trifluoroacetate salt LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-LEU: KRPPGFSPL Lys-(Des-Arg9,Leu8)-Bradykinin (Des-Arg10,Leu9)-Kallidin 1-9-Kallidin, 9-L-leucine- Lys-(Des-Arg9,Leu8)-Bradykinin trifluoroacetate salt H-Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Leu-OH trifluoroacetate salt 9-L-Leucine-1-9-kallidin Lys-(Des-Arg?,Leu?)-Bradykinin 71800-37-8 C47H75N13O11