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Pheniramine maleate

Pheniramine maleate Structure
Pheniramine maleate structure
CAS No.
132-20-7
Chemical Name:
Pheniramine maleate
Synonyms
Pheneramine Maleate;PHENIRAMINE MALEATE SALT;pm241;Fervex;daneral;ho11513;inhiston;Trimetose;205-051-4;Antolozine
CBNumber:
CB9727768
Molecular Formula:
C20H24N2O4
Molecular Weight:
356.42
MDL Number:
MFCD00079250
MOL File:
132-20-7.mol
Last updated:2024-12-18 14:15:32
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Pheniramine maleate Properties

Melting point 104-108°C
Boiling point 489.25°C (rough estimate)
Density 1.2233 (rough estimate)
refractive index 1.6800 (estimate)
storage temp. 2-8°C
solubility Very soluble in water, freely soluble in ethanol (96 per cent), in methanol and in methylene chloride.
form Solid
color White
Water Solubility >=1 g/100 mL at 24 ºC
λmax 262nm(lit.)
Merck 14,7235
Stability Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference 132-20-7(CAS DataBase Reference)
FDA 21 CFR 310.545; 341.12
EWG's Food Scores 1
FDA UNII NYW905655B
EPA Substance Registry System Pheniramine maleate (132-20-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
Hazard Codes  Xn
Risk Statements  22
Safety Statements  36
WGK Germany  3
RTECS  UT0175000
HS Code  2933399090

Pheniramine maleate price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR2646 Pheniramine Maleate Pharmaceutical Secondary Standard; Certified Reference Material 132-20-7 300MG $200 2024-03-01 Buy
Sigma-Aldrich P6902 Pheniramine maleate salt 132-20-7 5g $162 2024-03-01 Buy
Sigma-Aldrich 1522301 Pheniramine maleate United States Pharmacopeia (USP) Reference Standard 132-20-7 150mg $436 2024-03-01 Buy
TCI Chemical P2271 Pheniramine Maleate >98.0%(HPLC)(T) 132-20-7 25g $139 2024-03-01 Buy
Sigma-Aldrich P0850000 Pheniramine maleate European Pharmacopoeia (EP) Reference Standard 132-20-7 p0850000 $153 2024-03-01 Buy
Product number Packaging Price Buy
PHR2646 300MG $200 Buy
P6902 5g $162 Buy
1522301 150mg $436 Buy
P2271 25g $139 Buy
P0850000 p0850000 $153 Buy

Pheniramine maleate Chemical Properties,Uses,Production

Chemical Properties

white powder

Originator

Trimeton Maleate, Schering ,US,1948

Uses

Pheniramine, a H1-receptor antagonist, is an antihistamine with anticholinergic and sedative properties. Pheniramine is used to treat allergic conditions such as hay fever or urticaria.

Definition

ChEBI: Pheniramine maleate is an organic molecular entity.

Manufacturing Process

According to US Patent 2,676,964: to 1.0 mol of potassium amide in 3 liters of liquid ammonia, is added 1.0 mol of 2-benzylpyridine. After 15 minutes, 1.1 mols of β-dimethylaminoethyl chloride are added. The ammonia is allowed to evaporate and the reaction product decomposed with water and ether extracted. The ether layer is dried over sodium sulfate and after evaporation the residue is distilled, giving the Pheniramine, BP 139°-142°C/1-2 mm. The Pheniramine maleate is produced by reaction with maleic acid.

Therapeutic Function

Antihistaminic

General Description

White powder with a faint amine-like odor. Melting point 107°C. pH (1% solution) 4.5-5.5. Used medicinally as an antihistaminic.

General Description

Pheniramine maleate, 2-[α-[2-dimethylaminoethyl]benzyl]-pyridine bimaleate (Trimeton,Inhiston), is a white crystalline powder, with a faint aminelikeodor, which is soluble in water (1:5) and very soluble inalcohol. This drug is the least potent member of the seriesand is marketed as the racemate. The usual adult dose is 20to 40 mg 3 times daily. It is available in certain combinationproducts.

Air & Water Reactions

Water soluble.

Reactivity Profile

Pheniramine maleate gives weakly acidic aqueous solutions. May react with strong oxidizing agents.

Fire Hazard

Flash point data are not available for Pheniramine maleate, but Pheniramine maleate is probably combustible.

Biochem/physiol Actions

Pheniramine maleate is a H1 histamine receptor antagonist. It is an alkylamine derivative. Structurally, pheniramine contains a chiral carbon atom with a hydrogen atom. Other substituents include the pyridyl, alkylamine and phenyl groups. It is used as an antiallergic drug for treating the common cold, respiratory allergies, urticaria, and systematic allergic reactions.

Side effects

Drowsiness, dizziness, dry mouth/nose/throat, headache, upset stomach, constipation, or trouble sleeping may occur. 

Pheniramine maleate Preparation Products And Raw materials

Raw materials

POTASSIUM AMIDE Maleic acid 2-Benzylpyridine

Preparation Products

Pheniramine maleate Suppliers

Global( 378)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd 		+86 13288715578 +8613288715578 sales@hbmojin.com China 12834 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29791 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
Hangzhou FandaChem Co.,Ltd. 		+8615858145714 FandaChem@Gmail.com China 9084 55
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29880 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28172 58
Hebei Weibang Biotechnology Co., Ltd 		+8615531157085 abby@weibangbio.com China 8807 58
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22963 58
Shanghai Longyu Biotechnology Co., Ltd. 		+8619521488211 info@longyupharma.com China 2541 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
Supplier Advantage
Hebei Mojin Biotechnology Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
Hangzhou FandaChem Co.,Ltd. 		55
career henan chemical co 		58
Hubei Jusheng Technology Co.,Ltd. 		58
Hebei Weibang Biotechnology Co., Ltd 		58
Hubei xin bonus chemical co. LTD 		58
Shanghai Longyu Biotechnology Co., Ltd. 		58
Chongqing Chemdad Co., Ltd 		58

Related articles

View Lastest Price from Pheniramine maleate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Pheniramine maleate pictures 2024-12-13 Pheniramine maleate
132-20-7
 US $0.00 / KG 1KG 98%min 100KG WUHAN FORTUNA CHEMICAL CO., LTD
Pheniramine maleate pictures 2024-11-19 Pheniramine maleate
132-20-7
 US $93.00-50.00 / mg 99.79% 10g TargetMol Chemicals Inc.
Pheniramine maleate pictures 2024-11-19 Pheniramine maleate
132-20-7
 US $93.00-50.00 / mg 99.79% 10g TargetMol Chemicals Inc.

Pheniramine maleate Spectrum

Pheniramine maleate(132-20-7)1HNMR

132-20-7(Pheniramine maleate)Related Search:

Trimebutine maleate Pheniramine Maleic acid Chlorphenamine maleate PHENYL VALERATE
Rosiglitazone maleate TRIS MALEATE Disodium fumarate Phenyl salicylate Cinepazide maleate
Enalapril maleate Dibutyl phthalate Diphenyldimethoxysilane 4-Dimethylaminopyridine Diphenyl ether
Brompheniramine PHENYL RESIN Phenylacetic acid

1of4

PROPHENPYRIDAMINE MALEATE PHENIRAMINE MALEATE inhiston n,n-dimethyl-gamma-phenyl-2-pyridinepropanamin(z)-2-butenedioate(1:1) pheniraminehydrogenmaleate phenyl(2-pyridyl)(beta-n,n-dimethylaminomethyl)methanemaleate pm241 trimetonmaleate 1-phenyl-1-(2-pyridyl)-3-dimethylaminopropane maleate 2-[ALPHA-(2-DIMETHYLAMINOETHYL) BENZYL]PYRIDINE MALEATE SALT But-2-enedioic acid N,N-dimethyl-3-phenyl-3-pyridin-2-ylpropan-1-amine Pyridine, 2-(alpha-(2-(dimethylamino)ethyl)benzyl)-, maleate (1:1) Trimetose N,N-Dimethyl-3-phenyl-3-(2-pyridyl)propane-1-amine·maleic acid HeniraMine Maleate Pheniramine Maleate (150 mg) 2-[α-[2-(DiMethylaMino)ethyl]benzyl]pyridine Maleate Antolozine Fervex N,N-DiMethyl-γ-phenyl-2-pyridinepropanaMine (2Z)-2-Butenedioate 2-Pyridinepropanamine, N,N-dimethyl-γ-phenyl-, (2Z)-2-butenedioate (1:1) 2-Pyridinepropanamine, N,N-dimethyl-.gamma.-phenyl-, (2Z)-2-butenedioate (1:1) PHENIRAMINEMALEATE,BP 205-051-4 4-CYANO PRYIDINE (PHENIRAMINE MALEATE) PHENIRAMIN MALEATE 1-(n,n-dimethylamino)-3-(phenyl-3-alpha-pyridyl)propanemaleate 2-(alpha-(2-(dimethylamino)ethyl)benzyl)pyridine,bimaleate 2-(alpha-(2-(dimethylamino)ethyl)benzyl)pyridine,maleate 2-(alpha-(2-(dimethylamino)ethyl)benzyl)-pyridinmaleate(1:1) avil-retard daneral ho11513 dimethyl-[3-phenyl-3-(2-pyridin-1-iumyl)propyl]ammonium Dexchlorpheniramine Impurity 1 (Dexchlorpheniramine EP Impurity A) Chlorpheniramine Impurity G Pheniramine maleate CRS Pheniramine maleate USP/EP/BP N,N-dimethyl-3-phenyl-3-(pyridin-2-yl)propan-1-amine maleate Pheniramine maleateQ: What is Pheniramine maleate Q: What is the CAS Number of Pheniramine maleate Q: What is the storage condition of Pheniramine maleate Q: What are the applications of Pheniramine maleate Pheniramine Maleate (1522301) (3RS)-N,N-Dimethyl-3-phenyl-3-(pyridin-2-yl)propan-1-amine (Pheniramine) Pheniramine Maleate （Dexchlorpheniramine EP Impurity A Maleate Salt） PHENIRAMINE MALEATE SALT Pheneramine Maleate Dexchlorpheniramine Maleate EP Impurity A as Maleate Dextrochlorobenzamine maleate EP impurity A Brompheniramine Maleate EP Impurity C as Maleate 132-20-7 C16H20N2C4H4O4 H1 histamine receptor antagonist. Antagonists Histaminergics Neurotransmitters Amines Aromatics Heterocycles Intermediates & Fine Chemicals