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20-CARBOXY-LEUKOTRIENE B4

CAS No.
80434-82-8
Chemical Name:
20-CARBOXY-LEUKOTRIENE B4
Synonyms
20-COOH-LTB4;20-CARBOXY-LEUKOTRIENE B4;20-hydroxy-20-oxoleukotriene B4;5S,12R-DIHYDROXY-6Z,8E,10E,14Z-EICOSATETRAENE-1,20-DIOIC ACID;(5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,14-tetraenedioic acid;6,8,10,14-Eicosatetraenedioic acid, 5,12-dihydroxy-, (5S,6Z,8E,10E,12R,14Z)-
CBNumber:
CB9769067
Molecular Formula:
C20H30O6
Molecular Weight:
366.45
MDL Number:
MFCD00065857
MOL File:
80434-82-8.mol
Last updated:2024-07-02 08:55:42

20-CARBOXY-LEUKOTRIENE B4 Properties

Boiling point 588.3±50.0 °C(Predicted)
Density 1.151±0.06 g/cm3(Predicted)
Flash point 14℃
storage temp. −20°C
solubility DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml
form Liquid
pka 4.66±0.10(Predicted)
color Colorless to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H315-H319-H335
Precautionary statements  P210-P261-P305+P351+P338
Hazard Codes  F,Xi
Risk Statements  11-36/37/38
Safety Statements  16-26-36
RIDADR  UN 1170 3/PG 2
WGK Germany  3
NFPA 704
3
0 0

20-CARBOXY-LEUKOTRIENE B4 price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C6046 20-Carboxy-leukotriene B4 ~1?mg/mL in ethanol, ≥90% (HPLC) 80434-82-8 25μg $428 2023-06-20 Buy
Cayman Chemical 20180 20-carboxy Leukotriene B4 ≥97% 80434-82-8 25μg $174 2024-03-01 Buy
Cayman Chemical 20180 20-carboxy Leukotriene B4 ≥97% 80434-82-8 50μg $328 2024-03-01 Buy
Cayman Chemical 20180 20-carboxy Leukotriene B4 ≥97% 80434-82-8 100μg $618 2024-03-01 Buy
TRC C724805 20-COOH-LTB4 80434-82-8 100μg $540 2021-12-16 Buy
Product number Packaging Price Buy
C6046 25μg $428 Buy
20180 25μg $174 Buy
20180 50μg $328 Buy
20180 100μg $618 Buy
C724805 100μg $540 Buy

20-CARBOXY-LEUKOTRIENE B4 Chemical Properties,Uses,Production

Description

20-carboxy LTB4 is a metabolite of LTB4 in human neutrophils. In human leukocytes, LTB4 is inactivated by the enzyme LTB4 20-hydroxylase. The resulting 20-hydroxy LTB4 is further oxidized to 20-carboxy LTB4. LTB4 metabolism in isolated rat hepatocytes also results in production of 20-carboxy LTB4 along with other ω-oxidation products. The biological activity of 20-carboxy LTB4 is only about 2.6% compared to that of LTB4 in causing PMNL degranulation.

Uses

20-COOH-LTB4 is a leukotriene B4 metabolite and substrate for β-oxidation pathways.

Definition

ChEBI: A member of the class of leukotrienes that is leukotriene B4 in which the terminal methyl group has undergone formal oxidation to the corresponding carboxylic acid.

20-CARBOXY-LEUKOTRIENE B4 Preparation Products And Raw materials

Raw materials

Preparation Products

20-CARBOXY-LEUKOTRIENE B4 Suppliers

Global( 26)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
amyjetsci 027-59626688 18771149750 sales@amyjet.com China 3003 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24644 58
Shanghai Yiyan Biotechnology Co. , Ltd. 021-69985186 13611928337 3427709316@qq.com China 7979 58
Shanghai Yingxin laboratory equipment Co., Ltd 021-021-59178156 15300768757 359382369@qq.com China 10674 58
Shanghai Guchen Biotechnology Co., LTD 021-34675735 19147740836 1986399151@qq.com China 9844 58
Hubei Danding Pharmaceutical Technology Co., Ltd 18917019315 181646821@qq.com China 9014 58
20-CARBOXY-LEUKOTRIENE B4 20-COOH-LTB4 5S,12R-DIHYDROXY-6Z,8E,10E,14Z-EICOSATETRAENE-1,20-DIOIC ACID (5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,14-tetraenedioic acid 20-hydroxy-20-oxoleukotriene B4 6,8,10,14-Eicosatetraenedioic acid, 5,12-dihydroxy-, (5S,6Z,8E,10E,12R,14Z)- 80434-82-8 C20H30O6 Lipids Fatty Acids Biochemicals and Reagents BioChemical Leukotrienes Fatty Acids Leukotrienes Lipids