ChemicalBook >> CAS DataBase List >>2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE

2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE

CAS No.
149847-77-8
Chemical Name:
2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE
Synonyms
2-MPMDQ;2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE;2-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)-6-methyl-2,6-dihydroimidazo[1,2-c]quinazolin-5(3H)-one;Imidazo[1,2-c]quinazolin-5(3H)-one, 2,6-dihydro-2-[[4-(2-methoxyphenyl)-1-piperazinyl]methyl]-6-methyl-
CBNumber:
CB9771332
Molecular Formula:
C23H27N5O2
Molecular Weight:
405.49
MDL Number:
MFCD00673888
MOL File:
Mol file
Last updated:2023-05-18 11:31:02

2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE Properties

storage temp. Store at RT
solubility <20.27mg/ml in DMSO
form Powder

2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 0661 2-MPMDQ 149847-77-8 10 $154 2021-12-16 Buy
Tocris 0661 2-MPMDQ 149847-77-8 50 $628 2021-12-16 Buy
TRC M745853 2-MPMDQ 149847-77-8 2.5mg $195 2021-12-16 Buy
TRC M745853 2-MPMDQ 149847-77-8 5mg $330 2021-12-16 Buy
Usbiological 254368 2-MPMDQ 149847-77-8 10mg $403 2021-12-16 Buy
Product number Packaging Price Buy
0661 10 $154 Buy
0661 50 $628 Buy
M745853 2.5mg $195 Buy
M745853 5mg $330 Buy
254368 10mg $403 Buy

2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE Chemical Properties,Uses,Production

Uses

2-MPMDQ is a novel class of α1-adrenoceptor antagonists and acts as an anti-hypertensive agent.

Definition

ChEBI: 2-[[4-(2-methoxyphenyl)-1-piperazinyl]methyl]-6-methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5-one is a member of piperazines.

Biological Activity

Potent and selective α 1 -adrenoceptor antagonist; hypotensive.

References

[1]. chern jw, tao pl, yen mh, et al. studies on quinazolines. 5. 2,3-dihydroimidazo[1,2-c]quinazoline derivatives: a novel class of potent and selective alpha 1-adrenoceptor antagonists and antihypertensive agents. j med chem, 1993, 36(15): 2196-2207.

2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE Suppliers

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Wuhan Topule Biopharmaceutical Co., Ltd
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EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8447 60
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Nantong Hanfang Biotechnology Co. , Ltd. 18616537568 hanfangpharma@126.com China 29971 58
ApexBio Technology -- sales@apexbt.com United States 6251 58
2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE 2-MPMDQ Imidazo[1,2-c]quinazolin-5(3H)-one, 2,6-dihydro-2-[[4-(2-methoxyphenyl)-1-piperazinyl]methyl]-6-methyl- 2-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)-6-methyl-2,6-dihydroimidazo[1,2-c]quinazolin-5(3H)-one 149847-77-8