ChemicalBook >> CAS DataBase List >>Keap1–Nrf2-IN-1
Keap1–Nrf2-IN-1
- CAS No.
- 2232112-72-8
- Chemical Name:
- Keap1–Nrf2-IN-1
- Synonyms
- Keap1–Nrf2-IN-1;Keap1 Nrf2 IN 1,Keap1Nrf2IN1,Keap-1-Nrf2-IN-1;L-Proline, 1-[4-[(carboxymethyl)[(4-methoxyphenyl)sulfonyl]amino]-1-naphthalenyl]-
- CBNumber:
- CB98054440
- Molecular Formula:
- C24H24N2O7S
- Molecular Weight:
- 484.52
- MDL Number:
- MOL File:
- 2232112-72-8.mol
Last updated:2023-05-21 10:59:17
Keap1–Nrf2-IN-1 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0100953 | Keap1-Nrf2-IN-1 98.08% | 2232112-72-8 | 5mg | $450 | 2021-12-16 | Buy |
| ChemScene | CS-0100953 | Keap1-Nrf2-IN-1 98.08% | 2232112-72-8 | 10mg | $750 | 2021-12-16 | Buy |
| ChemScene | CS-0100953 | Keap1-Nrf2-IN-1 98.08% | 2232112-72-8 | 50mg | $2250 | 2021-12-16 | Buy |
| ChemScene | CS-0100953 | Keap1-Nrf2-IN-1 98.08% | 2232112-72-8 | 100mg | $3350 | 2021-12-16 | Buy |
Keap1–Nrf2-IN-1 Chemical Properties,Uses,Production
Description
Keap1-Nrf2 IN-1 (compound35) is a Kelch-like ECH-associated protein 1-nuclear factor erythroid 2-related factor 2 (Keap1-Nrf2) protein-protein interaction inhibitor, and with an IC50 of 43 nM for Keap1 protein. Keap1-Nrf2 IN-1 (compound35) activates Nrf2-regulated cytoprotective response and antagonizes acetaminophen-induced liver injury both in cellular and in vivo models[1]. IC50: 43 nM (Keap1 protein)[1]
References
[1]. Lu MC, et al. Discovery of a Potent Kelch-Like ECH-Associated Protein 1-Nuclear Factor Erythroid 2-Related Factor 2 (Keap1-Nrf2) Protein-Protein Interaction Inhibitor with Natural Proline Structure as a Cytoprotective Agent against Acetaminophen-Induced Hepatotoxicity. J Med Chem. 2019 Jul 25;62(14):6796-6813.
Keap1–Nrf2-IN-1 Preparation Products And Raw materials
Raw materials
Preparation Products
Keap1–Nrf2-IN-1 Suppliers
Global( 4)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52924 | 58 |
| Chengdu Peter-like Biotechnology Co., Ltd. | 028-81700200 18108052721 | 2850505130@qq.com | China | 5173 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9266 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| Aladdin Scientific | 58 |
| Chengdu Peter-like Biotechnology Co., Ltd. | 58 |
| RD International Technology Co., Limited | 58 |
Keap1–Nrf2-IN-1
Keap1 Nrf2 IN 1,Keap1Nrf2IN1,Keap-1-Nrf2-IN-1
L-Proline, 1-[4-[(carboxymethyl)[(4-methoxyphenyl)sulfonyl]amino]-1-naphthalenyl]-
2232112-72-8