ChemicalBook >> CAS DataBase List >>INDEX NAME NOT YET ASSIGNED
INDEX NAME NOT YET ASSIGNED
- CAS No.
- 1895916-24-1
- Chemical Name:
- INDEX NAME NOT YET ASSIGNED
- Synonyms
- SuO-Glu-Val-Cit-PAB-MMAE
- CBNumber:
- CB98365816
- Molecular Formula:
- C67H103N11O17
- Molecular Weight:
- 1334.62
- MDL Number:
- MOL File:
- 1895916-24-1.mol
Last updated:2024-07-02 08:55:42
INDEX NAME NOT YET ASSIGNED Chemical Properties,Uses,Production
Biological Activity
SuO-Glu-Val-Cit-PAB-MMAE consists a cleavable ADC linker (SuO-Glu-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE). SuO-Glu-Val-Cit-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs)[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References
[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
INDEX NAME NOT YET ASSIGNED Preparation Products And Raw materials
Raw materials
Preparation Products
INDEX NAME NOT YET ASSIGNED Suppliers
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SuO-Glu-Val-Cit-PAB-MMAE
1895916-24-1
C67H103N11O17
ADC LINKER