9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)
- CAS No.
- 756499-04-4
- Chemical Name:
- 9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)
- Synonyms
- 11(E)-CLA;9(Z),11(E)-Conjugated Linoleic Acid (sodium salt);(9Z,11E)-9,11-octadecadienoic acid, monosodium salt
- CBNumber:
- CB98571031
- Molecular Formula:
- C18H33NaO2
- Molecular Weight:
- 304.45
- MDL Number:
- MOL File:
- 756499-04-4.mol
9(Z),11(E)-Conjugated Linoleic Acid (sodium salt) Chemical Properties,Uses,Production
Biological Activity
9(Z),11(E)-Conjugated linoleic acid is an isomer of linoleic acid that has been found in beef and milk fat.1 It binds to peroxisome proliferator-activated receptor α (PPARα; IC50 = 140 nM) and activates the receptor in a reporter assay using COS-1 cells expressing mouse PPARα when used at a concentration of 100 μM.2 9(Z),11(E)-Conjugated linoleic acid inhibits TNF-α-induced GLUT4 expression and increases insulin-stimulated glucose transport in 3T3-L1 adipocytes.3 Dietary administration of 9(Z)11(E)-conjugated linoleic acid reduces serum fasting glucose, insulin, and triglyceride levels and decreases white adipose tissue macrophage infiltration in ob/ob mice. It also increases body weight gain and body fat in weanling mice.4 [Matreya, LLC. Catalog No. 1278]
References
1.Shultz, T.D., Chew, B.P., Seaman, W.R., et al.Inhibitory effect of conjugated dienoic derivatives of linoleic acid and β-carotene on the in vitro growth of human cancer cellsCancer Lett.63(2)125-133(1992) 2.Moya-Camarena, S.Y., Heuvel, J.P.V., Blanchard, S.G., et al.Conjugated linoleic acid is a potent naturally occurring ligand and activator of PPARαJ. Lipid Res.40(8)1426-1433(1999) 3.Moloney, F., Toomey, S., Noone, E., et al.Antidiabetic effects of cis-9, trans-11-conjugated linoleic acid may be mediated via anti-inflammatory effects in white adipose tissueDiabetes56(3)574-582(2007) 4.Pariza, M.W., Park, Y., and Cook, M.E.The biologically active isomers of conjugated linoleic acidProg. Lipid Res.40(4)283-298(2001)
9(Z),11(E)-Conjugated Linoleic Acid (sodium salt) Preparation Products And Raw materials
Raw materials
Preparation Products
9(Z),11(E)-Conjugated Linoleic Acid (sodium salt) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 | 3477467573@qq.com | China | 8618 | 58 |
| Beijing Biocreative Technology Co., Ltd. | 15522676233 | 3007606172@qq.com | China | 1249 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8739 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 28118 | 58 |
| SHANGHAI ZZBIO CO., LTD. | 19921389125 19921389125 | tech@zzbioco.com | China | 12065 | 58 |