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(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride

(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride structure

CAS No.: 5843-53-8

Chemical Name:: (+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride

Synonyms: BA-7205;Rexigen;ClobenzorexHCl;Einecs 227-434-5;(S)-(+)-Clobenzorex Hydrochloride;N-(2-chlorobenzyl)-1-phenylpropan-2-amine hydrochloride;Chlorhydrate de D-N-(phenyl-1 propyl-2) chloro-2 benzylamine;(2-chlorobenzyl)-(1-methyl-2-phenyl-ethyl)amine hydrochloride;N-[(2-chlorophenyl)methyl]-1-phenylpropan-2-amine hydrochloride;(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride

CBNumber:: CB9928091

Molecular Formula:: C16H19Cl2N

Molecular Weight:: 296.23476

MDL Number:: MFCD00242899

MOL File:: 5843-53-8.mol

Last updated:2023-05-15 10:44:01

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(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride Properties

Melting point	182-183° (isopropanol)
alpha	D20 +26.3° (water)
solubility	Methanol (Slightly), Water (Slightly, Heated)
form	Solid
color	White to Off-White
EWG's Food Scores	1
FDA UNII	BC6X5MB664

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P264-P270-P301+P312-P330-P501
Toxicity	LD50 i.p. in mice: 103 mg/kg (Boissier et al.)

(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth Carbosynth	FC131572	N-(2-Chlorobenzyl)-1-phenylpropan-2-amine hydrochloride	5843-53-8	250mg	$57.5	2021-12-16	Buy
Biosynth Carbosynth	FC131572	N-(2-Chlorobenzyl)-1-phenylpropan-2-amine hydrochloride	5843-53-8	500mg	$100	2021-12-16	Buy
Matrix Scientific	155683	N-(2-Chlorobenzyl)-1-phenylpropan-2-amine hydrochloride	5843-53-8	0.500g	$160	2021-12-16	Buy
Biosynth Carbosynth	FC131572	N-(2-Chlorobenzyl)-1-phenylpropan-2-amine hydrochloride	5843-53-8	1g	$170	2021-12-16	Buy
Matrix Scientific	155683	N-(2-Chlorobenzyl)-1-phenylpropan-2-amine hydrochloride	5843-53-8	1g	$200	2021-12-16	Buy

Product number	Packaging	Price	Buy
FC131572	250mg	$57.5	Buy
FC131572	500mg	$100	Buy
155683	0.500g	$160	Buy
FC131572	1g	$170	Buy
155683	1g	$200	Buy

(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride Chemical Properties,Uses,Production

Chemical Properties

White Solid

Originator

Asenlix,Aventis

Uses

The S-enantiomer of Clobenzorex (C583000), an anorexic.

Manufacturing Process

A solution of 21.0 g (0.15 mol) of 2-chlorobenzaldehyde in 100 ml of ethanol (95%) was added to a solution of 20.5 g (0.152 mol) of D-1-phenyl-2-aminopropane in 100 ml of ethanol (95%). After standing for 15 h at room temperature, the ethanol was driven off, and the oily residue was then distilled to yield 36.2 g (94%) of D-N-(2-chlorobenzylidene)-2-amino-1- phenylpropane, boiling point 142°-146°C/0.1 mm Hg.
To the solution of 36.0 g (0.14 mol) of D-N-(2-chlorobenzylidene)-2-amino-1- phenylpropane in 200 ml of dry methanol were added, in portions, 5.3 g (0.14 mol) of sodium borohydride. The mixture was stirred for 1 h at room
temperature, and refluxed for 1 h water (100 ml) was then added and the methanol was removed in vacuo. After acidifying carefully with dilute hydrochloric acid, the solution was made alkaline by dilute sodium hydroxide, and extracted with ether. 33.0 g (90%) of D-N-(1-phenyl-2-propyl)-2-
chlorobenzylamine, boiling point 132°-134°C/0.1 mm Hg, were obtained by distillation.

Therapeutic Function

Anorexic

(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride Preparation Products And Raw materials

Raw materials

D-AMPHETAMINE HYDROCHLORIDE Sodium hydroxide 2-Chlorobenzaldehyde

Preparation Products

(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride Suppliers

Global( 22)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32956	60
Dorne Chemical Technology co. LTD	+86-86-13583358881 +8618560316533	Ethan@dornechem.com	China	3096	58
Guangzhou CATO Research Chemicals Inc.	+86-020-81960175-617 +8615602392859	Intermediate@cato-chem.com	China	8047	58
Chizhou Kailong Import and Export Trade Co., Ltd.		xg01_gj@163.com	China	9484	50
Shanghai SuperLan Chemcial Technique Centre	021-2022843681 15618226720	lucy@atkchemical.com	China	9952	58
Angel Pharmatech, Ltd.	17317130613	3358272972@qq.com	China	3253	58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.	021-51816796-820 13611835272	sales2@sunwaypharm.com	China	44458	58
Hangzhou Taorui Biotechnology Co., Ltd	4000-360-990 15268198094	sales@torreybio.com	China	2885	58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd	15229059051	1027@dideu.com	China	10003	58
Pushan Industry (Shaanxi) Co., Ltd.	029-81310890 13571859809	info@pushanshiye.com	China	10000	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
Dorne Chemical Technology co. LTD	58
Guangzhou CATO Research Chemicals Inc.	58
Chizhou Kailong Import and Export Trade Co., Ltd.	50
Shanghai SuperLan Chemcial Technique Centre	58
Angel Pharmatech, Ltd.	58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.	58
Hangzhou Taorui Biotechnology Co., Ltd	58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd	58
Pushan Industry (Shaanxi) Co., Ltd.	58

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BenzeneethanaMine,N-[(2-chlorophenyl)Methyl]-a-Methyl-, hydrochloride (1:1), (+)- (2-chlorobenzyl)-(1-methyl-2-phenyl-ethyl)amine hydrochloride N-(2-chlorobenzyl)-1-phenylpropan-2-amine hydrochloride BA-7205 Chlorhydrate de D-N-(phenyl-1 propyl-2) chloro-2 benzylamine Chlorhydrate de D-N-(phenyl-1 propyl-2) chloro-2 benzylamine [french] Einecs 227-434-5 (S)-(+)-Clobenzorex Hydrochloride N-[(2-chlorophenyl)methyl]-1-phenyl-propan-2-amine hydrochloride N-[(2-chlorophenyl)methyl]-1-phenylpropan-2-amine hydrochloride Phenethylamine, N-(o-chlorobenzyl)-alpha-methyl-, hydrochloride, (+)- Rexigen (+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride ClobenzorexHCl (2S)-N-[(2-chlorophenyl)methyl]-1-phenylpropan-2-amine:hydrochloride (+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride 5843-53-8 Amines Aromatics Intermediates & Fine Chemicals Pharmaceuticals