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1H-Pyrrole-3-carboxamide, 5-(2-amino-4-pyrimidinyl)-2-[2-chloro-5-(trifluoromethyl)phenyl]-

1H-Pyrrole-3-carboxamide, 5-(2-amino-4-pyrimidinyl)-2-[2-chloro-5-(trifluoromethyl)phenyl]- Structure
1H-Pyrrole-3-carboxamide, 5-(2-amino-4-pyrimidinyl)-2-[2-chloro-5-(trifluoromethyl)phenyl]- structure
CAS No.
1403679-33-3
Chemical Name:
1H-Pyrrole-3-carboxamide, 5-(2-amino-4-pyrimidinyl)-2-[2-chloro-5-(trifluoromethyl)phenyl]-
Synonyms
NMS-P953;1H-Pyrrole-3-carboxamide, 5-(2-amino-4-pyrimidinyl)-2-[2-chloro-5-(trifluoromethyl)phenyl]-
CBNumber:
CB99755627
Molecular Formula:
C16H11ClF3N5O
Molecular Weight:
381.74
MDL Number:
MOL File:
1403679-33-3.mol
Last updated:2024-10-28 16:48:35
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1H-Pyrrole-3-carboxamide, 5-(2-amino-4-pyrimidinyl)-2-[2-chloro-5-(trifluoromethyl)phenyl]- Properties

Boiling point 602.8±65.0 °C(Predicted)
Density 1.519±0.06 g/cm3(Predicted)
pka 11.92±0.50(Predicted)

1H-Pyrrole-3-carboxamide, 5-(2-amino-4-pyrimidinyl)-2-[2-chloro-5-(trifluoromethyl)phenyl]- Chemical Properties,Uses,Production

Description

NMS-P953 is a JAK2 inhibitor, displaying significant tumor growth inhibition in SET-?2 xenograft tumor model. NMS-P953 has a mechanism of action confirmed in vivo by typical modulation of known biomarkers, and with a favorable pharmacokinetic and safety profile.

1H-Pyrrole-3-carboxamide, 5-(2-amino-4-pyrimidinyl)-2-[2-chloro-5-(trifluoromethyl)phenyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Pyrrole-3-carboxamide, 5-(2-amino-4-pyrimidinyl)-2-[2-chloro-5-(trifluoromethyl)phenyl]- Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+8613564774135 zijue.cai@tsbiochem.com United States 19863 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19711 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
TargetMol Chemicals Inc. 58

View Lastest Price from 1H-Pyrrole-3-carboxamide, 5-(2-amino-4-pyrimidinyl)-2-[2-chloro-5-(trifluoromethyl)phenyl]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
NMS-P953 pictures 2024-10-28 NMS-P953
1403679-33-3
 US $3700.00-2120.00 / mg 10g TargetMol Chemicals Inc.
  • NMS-P953 pictures
  • NMS-P953
    1403679-33-3
  • US $3700.00-2120.00 / mg
  • TargetMol Chemicals Inc.
1H-Pyrrole-3-carboxamide, 5-(2-amino-4-pyrimidinyl)-2-[2-chloro-5-(trifluoromethyl)phenyl]- NMS-P953 1403679-33-3