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Udenafil

Udenafil Structure
CAS No.
268203-93-6
Chemical Name:
Udenafil
Synonyms
Zydena;Da-8159;Da 8159;Udenafi;CS-1353;Udenafil;Udenafil, >=98%;Udenafil, DA 8159;Udenafil(DA 8159,Zydena);Udenafil Solution, 100ppm
CBNumber:
CB01508622
Molecular Formula:
C25H36N6O4S
Molecular Weight:
516.66
MOL File:
268203-93-6.mol
Modify Date:
2023/9/11 16:43:46
Request For Quotation

Udenafil Properties

Melting point 152-159°C
Boiling point 697.0±65.0 °C(Predicted)
Density 1.35
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Chloroform (Slightly), Methanol (Sparingly)
form Solid
pka 11.07±0.50(Predicted)
color White to Pale Beige

Udenafil Chemical Properties,Uses,Production

Description

Udenafil is the fourth in a class of drugs targeting the inhibition of the enzyme phosphodiesterase 5 (PDE5) for the treatment of erectile dysfunction. Inhibition of PDE5 results in the increase in endogenous cyclic guanosine monophosphate (cGMP) concentrations in the penile corpus cavernosum. cGMP induces smooth muscle cell relaxation and subsequent increased blood flow leading to a sustainable erection. Udenafil is a potent antagonist of human PDE5 with an IC50 of 8.25nM and a comparable selectivity profile as sildenafil for the other PDEs. Unlike tadalafil, it does not inhibit PDE11, which has been implicated in myalgia and testicular toxicity. Furthermore, udenafil produced up to a 91% vaginal penetration success rate and up to a 67% intercourse completion rate compared to a 29% completion rate by placebo. Overall patient satisfaction, measured by a standard global assessment question, was 86% compared to only 26% in the placebo group. The most frequently recorded adverse events were mild-to-moderate facial flushing and headache.

Chemical Properties

Off-White Solid

Uses

Udenafil is an oral phosphodiesterase 5 inhibitor used for the treatment of erectile dysfunction.

Udenafil Preparation Products And Raw materials

Raw materials

Preparation Products

Udenafil Suppliers

Global( 132)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Rakshit Group of Companies (Rakshit Drugs Pvt Ltd) +91-4023810385 +91-9246228579 Telangana, India 36 58 Inquiry
DR REDDYS LABORATORIES LTD +91-40-49002900 New Delhi, India 201 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Hebei Yanxi Chemical Co., Ltd. +8617531190177 China 5873 58 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21667 55 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49392 58 Inquiry
Hebei Mojin Biotechnology Co., Ltd +86 13288715578 +8613288715578 China 12446 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
ANHUI WITOP BIOTECH CO., LTD +8615255079626 China 23555 58 Inquiry
Supplier Advantage
Rakshit Group of Companies (Rakshit Drugs Pvt Ltd) 58
DR REDDYS LABORATORIES LTD 58
CLEARSYNTH LABS LTD. 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Hebei Yanxi Chemical Co., Ltd. 58
Henan Tianfu Chemical Co.,Ltd. 55
CONIER CHEM AND PHARMA LIMITED 58
Hebei Mojin Biotechnology Co., Ltd 58
TargetMol Chemicals Inc. 58
ANHUI WITOP BIOTECH CO., LTD 58

Udenafil Spectrum

Udenafil(268203-93-6)MS

268203-93-6(Udenafil)Related Search:

Avanafil MIRODENAFIL Vardenafil hydrochloride Sildenafil
Benzenesulfonamide, 3-(4,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-D)pyrimidin-5-yl)-N-(2-(1-methyl-2-pyrrolidinyl)ethyl)-4-propoxy- Da 8159 Da-8159 3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-(2-(1-methylpyrrolidin-2-yl)ethyl)-4-propoxybenzenesulfonamide Udenafil Udenafi 3-(6,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]-4-propoxybenzenesulfonamide 5-[2-propyloxy-5-(2-(1-Methylpyrrolidin-2-yl)ethylaMinosulphonyl)phenyl]-1-Methyl-3-propyl-6,7-dihydro-1H-pyrazolo(4,3-d)pyriMidin-7-one 5-[2-propyloxy-5-[2-(1-Methyl-2-pyrrolidinyl)ethylaMinosulfonyl]phenyl]-1-Methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyriMidine-7-one Zydena Udenafil(DA 8159,Zydena) BenzenesulfonaMide,3-(6,7-dihydro-1-Methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyriMidin-5-yl)-N-[2-(1-Methyl-2-pyrrolidinyl)ethyl]-4-propoxy- Udenafil, >=98% 5-(2-Propyloxy-5-(1-methyl-2-pyrollidinylethylamidosulfonyl)phenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo(4,3-D)pyrimidine-7-one Udenafil Solution, 100ppm CAS No.268203-93-6 Udenafil Udenafil, DA 8159 CS-1353 268203-93-6 C25H36N6O3S2 Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals