Thiosildenafil

CAS No.: 479073-79-5

Chemical Name:: Thiosildenafil

Synonyms: xidi;Sildenafil N;Thiosildenafil;Sildenafil Impurity N;Pinacolborane Impurity 5;Demethyltadalafil Solution, 100ppm;ethyl4-amino-1-methyl-3-propyl-1H-pyrazole-5-carboxylate;5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidine-7-thione;5-(2-ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidine-7(6H)-thione;7H-Pyrazolo[4,3-d]pyrimidine-7-thione, 5-[2-ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-

CBNumber:: CB02104269

Molecular Formula:: C22H30N6O3S2

Molecular Weight:: 490.64

MOL File:: 479073-79-5.mol

Modify Date:: 2023/6/8 9:03:09

Request For Quotation

Thiosildenafil Properties

Melting point	172-174?C
Boiling point	676.1±65.0 °C(Predicted)
Density	1.39±0.1 g/cm3(Predicted)
storage temp.	Refrigerator
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Heated)
form	Solid
pka	5.97±0.42(Predicted)
color	Pale Yellow to Light Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501

NFPA 704

	0
2		0

Thiosildenafil Chemical Properties,Uses,Production

Description

Thiosildenafil is a derivative of the phosphodiesterase 5 (PDE5) inhibitor sildenafil .

Chemical Properties

Pale Yellow Solid

Uses

Sildenafil, marketed under the trade name Viagra?, is a potent cGMP-specific phosphodiesterase inhibitor that is highly selective for PDE5. While most notable for its use in the treatment of erectile dysfunction, sildenafil’s vasorelaxant properties have also been used to control vascular tone in pulmonary arterial hypertension and high-altitude pulmonary edema associated with altitude sickness. Thiosildenafil is a derivative of sildenafil that has been found as an adulterant in dietary supplements advertising sexual enhancement for men. The biological characteristics of thiosildenadil have not been reported.[Cayman Chemical]

Thiosildenafil Preparation Products And Raw materials

Raw materials

5-(2-Ethoxyphenyl)-1,6-dihydro-1-Methyl-3-propyl-7H-pyrazolo[4,3-d]pyriMidine-7-thione 5-(2-ETHOXYPHENYL)-1-METHYL-3-N-PROPYL-1,6-DIHYDRO-7H-PYRAZOLO[4,3-D]-7-PYRIMIDINONE 1-Methylpiperazine

Preparation Products

Thiosildenafil Suppliers

Global( 40)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
sgtlifesciences pvt ltd	+8617013299288	China	12382	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	52927	58	Inquiry
CHANG ZHOU A SANG QI TECHNOLOGY CO.,LTD	18961267976	China	499	58	Inquiry
Nantong Hanfang Biotechnology Co. , Ltd.	18616537568	China	30968	58	Inquiry
Changsha Manshuo Commercial and Trade Bank	18279085560 18279085560	China	29	58	Inquiry
Hubei Wanye Zhongcheng Chemical Reagent Co., Ltd.	18671296875	China	4302	58	Inquiry
TargetMol Chemicals Inc.	4008200310	China	24647	58	Inquiry
JIUWEI	13323819089	China	3	58	Inquiry
Shijiazhuang yaoBo Pharmaceutical Co., Ltd.	15633056635	China	2901	58	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
sgtlifesciences pvt ltd	58
Aladdin Scientific	58
CHANG ZHOU A SANG QI TECHNOLOGY CO.,LTD	58
Nantong Hanfang Biotechnology Co. , Ltd.	58
Changsha Manshuo Commercial and Trade Bank	58
Hubei Wanye Zhongcheng Chemical Reagent Co., Ltd.	58
TargetMol Chemicals Inc.	58
JIUWEI	58
Shijiazhuang yaoBo Pharmaceutical Co., Ltd.	58

479073-79-5(Thiosildenafil)Related Search:

Sildenafil EP IMpurity D Propoxyphenyl Sildenafil DESMETHYL SILDENAFIL Homo Sildenafil Sildenafil impurity

Sildenafil DiMer IMpurity SILDENAFIL N-OXIDE 7H-Pyrazolo[4,3-d]pyrimidin-7-one, 1,6-dihydro-5-(2-hydroxyphenyl)-1-methyl-3-propyl- 4-ethoxy-3-(1-methyl-7-oxo-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-5-yl)benzenesulfonamide 1-Methyl-4-nitro-3-propyl-(1H)-pyrazole-5-carboxamide

5-[2-Ethoxy-5-[(4-Methyl-4-oxido-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-Methyl-3-(2-Methylpropyl)-7H-pyrazolo[4,3-d]pyriMidin-7-one Desethyl Sildenafil 1-METHYL-4-NITRO-3-PROPYL-1H-PYRAZOLE-5-CARBOXYLIC ACID 1H-PYRAZOLE-5-CARBOXAMIDE, 4-[[2-ETHOXY-5-[(4-METHYL-1-PIPERAZINYL)SULFONYL]BENZOYL]AMINO]-1-METHYL-3-PROPYL- 4-AMINO-1-METHYL-5-PROPYL-1H-PYRAZOLE-3-CARBOXYLIC ACID AMIDE

Pyrazole N-Demethyl Sildenafil Sildenafil 5-[2-ethoxy-5-[4-(trideuteriomethyl)piperazin-1-yl]sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidine-7-thione

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Thiosildenafil Demethyltadalafil Solution, 100ppm 5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidine-7-thione Sildenafil N Sildenafil Impurity N Sildenafil Impurity 23/Thiosildenafil/5-(2-Ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidine-7-thione 7H-Pyrazolo[4,3-d]pyrimidine-7-thione, 5-[2-ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl- 5-(2-ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidine-7(6H)-thione xidi Pinacolborane Impurity 5 ethyl4-amino-1-methyl-3-propyl-1H-pyrazole-5-carboxylate 479073-79-5 171596-83-6 C22H27D3N6O3S2 C22H30N6O3S2 Drug Analogues Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds Isotope Labelled Compounds A 1