(3R,20S)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester

(3R,20S)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester Structure
CAS No.
14019-66-0
Chemical Name:
(3R,20S)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester
Synonyms
Uncarine F;(3R,20S)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester;(1'S,3R,4'aS,5'aR,10'aS)-1,2,5',5'a,7',8',10',10'a-Octahydro-1'-methyl-2-oxospiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid methyl ester;Spiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid, 1,2,5',5'a,7',8',10',10'a-octahydro-1'-methyl-2-oxo-, methyl ester, (1'S,3R,4'aS,5'aR,10'aS)-
CBNumber:
CB02362913
Molecular Formula:
C21H24N2O4
Molecular Weight:
368.43
MOL File:
14019-66-0.mol
Modify Date:
2023/5/4 17:34:33

(3R,20S)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester Properties

Boiling point 555.2±50.0 °C(Predicted)
Density 1.33
pka 13.56±0.60(Predicted)

(3R,20S)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester Chemical Properties,Uses,Production

Description

An Uncaria alkaloid, this base forms a colourless, non-crystallizable glass. The specific rotation is [α]D + 84° (CHCI3 ). It is stereoisomeric with the other alkaloids of this species just described.

References

Hart, Johns, Lamberton., Chem. Commun., 87 (1967)
Hemingway, Phillipson., J. Pharm. Pharmacol., 24, 169P (1972)
Circular dichroism: Beecham et al., Tetrahedron Lett., 991 (1967)

(3R,20S)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

(3R,20S)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester Suppliers

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(3R,20S)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester (1'S,3R,4'aS,5'aR,10'aS)-1,2,5',5'a,7',8',10',10'a-Octahydro-1'-methyl-2-oxospiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid methyl ester Uncarine F Spiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid, 1,2,5',5'a,7',8',10',10'a-octahydro-1'-methyl-2-oxo-, methyl ester, (1'S,3R,4'aS,5'aR,10'aS)- 14019-66-0