methyl 1-methyl-1H-pyrazole-3-carboxylate
- CAS No.
- 17827-61-1
- Chemical Name:
- methyl 1-methyl-1H-pyrazole-3-carboxylate
- Synonyms
- Methyl 1-Methylpyrazole-3-carboxylate;Methyl 1-methyl-1H-pyrazol-3-carboxylate;methyl 1-methyl-1H-pyrazole-3-carboxylate
- CBNumber:
- CB02522883
- Molecular Formula:
- C6H8N2O2
- Molecular Weight:
- 140.14
- MOL File:
- 17827-61-1.mol
- Modify Date:
- 2023/5/12 14:13:59
| Boiling point | 108-110 °C(Press: 1 Torr) |
|---|---|
| Density | 1.18±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | -0.17±0.10(Predicted) |
| InChI | InChI=1S/C6H8N2O2/c1-8-4-3-5(7-8)6(9)10-2/h3-4H,1-2H3 |
| InChIKey | WUUOFOYBXXQAGD-UHFFFAOYSA-N |
| SMILES | N1(C)C=CC(C(OC)=O)=N1 |
| CAS DataBase Reference | 17827-61-1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS02 |
|---|---|
| Signal word | Danger |
| Hazard statements | H314-H226 |
| Precautionary statements | P501-P240-P210-P233-P243-P241-P242-P264-P280-P370+P378-P303+P361+P353-P301+P330+P331-P363-P304+P340+P310-P305+P351+P338+P310-P403+P235-P405 |
| HS Code | 2933199090 |
methyl 1-methyl-1H-pyrazole-3-carboxylate Chemical Properties,Uses,Production
Uses
Used as an intermediate in organic synthesis.
Synthesis
A mixture of 2.11 g of pyrazole-3-carboxylic acid (V), 50 ml of methanol, and 0.5 ml of POCl3 was refluxed for 12 h. After cooling the reaction mixture was concentrated. The resulting crystals were washed with 20% sodium carbonate solution, dried at 55°C (1 mm Hg), and recrystallized from benzene. Methyl 1-methylpyrazole-3-carboxylate (VIII) was obtained similarly from 6.12 g of 1-methyl-3-pyrazole carboxylic acid VI, 50 ml of methanol and 0.5 ml of POCl3 . Yield 10.2 g (72.8%). bp 125°C (1 mm Hg). IR spectrum, ν, cm -1: 1520 (ring), 1730 (C═O). 1H NMR spectrum, δ, ppm (J, Hz): 3.77 s (3H, NCH3), 3.85 s (3H, OCH3), 6.68 d (1H, 4-H, J2.2), 7.1 br. s (1H, 5H). Found, %: C 51.63; H 5.85; N 20.28. C6H8N2O2. Calculated, %: C 51.42; H 5.71; N 20.00.
methyl 1-methyl-1H-pyrazole-3-carboxylate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29898 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | China | 34571 | 58 | Inquiry |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | China | 9624 | 58 | Inquiry |
| Henan Alfa Chemical Co., Ltd | +8618339805032 | China | 13140 | 58 | Inquiry |
| changzhou huayang technology co., ltd | +8615250961469 | China | 9827 | 58 | Inquiry |
| Nanjing Hengbei Chemicals Co., Ltd. | +86-25-58393656 | China | 6856 | 58 | Inquiry |