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4-(2-Bromoethynyl)benzoic acid

 4-(2-Bromoethynyl)benzoic acid Structure
CAS No.
1485684-77-2
Chemical Name:
4-(2-Bromoethynyl)benzoic acid
Synonyms
4- (broMoethynyl)benzoic acid;4-(2-bromoethynyl)benzoic acid;Benzoic acid, 4-(2-bromoethynyl)-;4-(2-BROMOETHYNYL)BENZOIC ACID(WXC01681)
CBNumber:
CB02677145
Molecular Formula:
C9H5BrO2
Molecular Weight:
225.04
MOL File:
1485684-77-2.mol
Modify Date:
2023/10/20 10:55:24

4-(2-Bromoethynyl)benzoic acid Chemical Properties,Uses,Production

Synthesis

To a solution of methyl 4,-(bromomethyl) benzoate (67 g, 250 mmol, 10 equiv) in (1100 mL) was added NaOH (44,84 g, 4,0 equiv) and the reaction mixture was stirred at 25°C for 3 hr. The volatiles were removed under reduced pressure and the resulting solution was neutralized with 1 HCl to pH 3-5. 4- (bromomethyl) benzoic acid (INT-1.5) was collected by filtration. The filter cake was washed with water and dried in an oven at 50°C for 5 hr to yield 4- (broMoethynyl)benzoic acid (61g, 96%).
    4- (broMoethynyl)benzoic acid

4-(2-Bromoethynyl)benzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

4-(2-Bromoethynyl)benzoic acid Suppliers

4- (broMoethynyl)benzoic acid 4-(2-bromoethynyl)benzoic acid 4-(2-BROMOETHYNYL)BENZOIC ACID(WXC01681) Benzoic acid, 4-(2-bromoethynyl)- 1485684-77-2