DM1-Sme
- CAS No.
- 138148-68-2
- Chemical Name:
- DM1-Sme
- Synonyms
- DM1-Sme;CS-2715;DM1-SSMe;AP3 Intermidate 2;DM1-SMe, 10 mM in DMSO;MaytansinoidDM4Impurity6;1H-Inden-2-ol,1-amino-2,3-dihydro-,(1R,4S)-;N2'-Deacetyl-N2'-[3-(methyldithio)-1-oxopropyl]maytansine;Maytansine, N2'-deacetyl-N2'-[3-(methyldithio)-1-oxopropyl]-;4,24-Dioxa-9,22-diazatetracyclo[19.3.1.1 10,14.03,5]hexacosane,maytansine deriv.
- CBNumber:
- CB03139071
- Molecular Formula:
- C36H50ClN3O10S2
- Molecular Weight:
- 784.38
- MOL File:
- 138148-68-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2025/4/18 9:51:28
| Boiling point | 957.1±65.0 °C(Predicted) |
|---|---|
| Density | 1.34±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility |
DMSO:12.0(Max Conc. mg/mL);15.3(Max Conc. mM) DMF:16.0(Max Conc. mg/mL);20.4(Max Conc. mM) DMF:PBS (pH 7.2) (1:5):0.16(Max Conc. mg/mL);0.2(Max Conc. mM) |
| form | A crystalline solid |
| pka | 9.82±0.70(Predicted) |
| color | Off-white to light yellow |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H303-H312-H315-H319-H361-H372-H317-H351-H335-H336-H412 |
| Precautionary statements | P501-P273-P272-P260-P270-P202-P201-P271-P264-P280-P312-P337+P313-P305+P351+P338-P362+P364-P333+P313-P302+P352+P312-P304+P340+P312-P403+P233-P405 |
DM1-Sme Preparation Products And Raw materials
Global( 60)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 33024 | 60 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19552 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 32159 | 58 | Inquiry |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10473 | 58 | Inquiry |
| InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6391 | 58 | Inquiry |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | China | 8467 | 58 | Inquiry |
| Aladdin Scientific | United States | 52924 | 58 | Inquiry | |
| Amadis Chemical Company Limited | 571-89925085 | China | 131957 | 58 | Inquiry |
| Shanghai Hao Zhun Biological Technology Co., Ltd. | 15800340161 | CHINA | 6650 | 58 | Inquiry |
| Shanghai Han-Xiang Chemical Co., Ltd. | +86 (21) 5027-2946, +86 13818785766 | China | 1037 | 50 | Inquiry |
DM1-Sme
N2'-Deacetyl-N2'-[3-(methyldithio)-1-oxopropyl]maytansine
(14S,16S,32S,33S,2R,4S,10E,12E,14R)-86-Chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl N-methyl-N-(3-(methyldisulfaneyl)propanoyl)-L-alaninate
4,24-Dioxa-9,22-diazatetracyclo[19.3.1.1 10,14.03,5]hexacosane,maytansine deriv.
Maytansine, N2'-deacetyl-N2'-[3-(methyldithio)-1-oxopropyl]-
maytansinoid derivative with ADC linker. Maytansine or mertansine or emtansine derivative
DM1-SSMe
DM1-SME; DM1-SSME; MAYTANSINOID DERIVATIVE WITH ADC LINKER. MAYTANSINE OR MERTANSINE OR EMTANSINE DERIVATIVE; N2'-DEACETYL-N2'-[3-(METHYLDITHIO)-1-OXOPROPYL]MAYTANSINE.
CS-2715
AP3 Intermidate 2
MaytansinoidDM4Impurity6
1H-Inden-2-ol,1-amino-2,3-dihydro-,(1R,4S)-
Microtubule/Tubulin,ADC Payload,anti-tumor activity,tumor cell,DM1 SMe,DM1-SMe,inhibit,Inhibitor,maytansinoid,ADC Cytotoxin,DM-1-SMe,antibody-drug conjugate,DM1SMe
(1S,2R,3S,5S,6R,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.11?,1?.03,?]hexacosa-10,12,14(26),16,18-pentaen-6-yl (2S)-2-[N-methyl-3-(methyldisulfanyl)propanamido]propanoate
DM1-SMe, 10 mM in DMSO
138148-68-2
C36H50ClN3O10S2