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DM1-Sme

DM1-Sme Structure
CAS No.
138148-68-2
Chemical Name:
DM1-Sme
Synonyms
DM1-Sme;CS-2715;DM1-SSMe;AP3 Intermidate 2;MaytansinoidDM4Impurity6;1H-Inden-2-ol,1-amino-2,3-dihydro-,(1R,4S)-;N2'-Deacetyl-N2'-[3-(methyldithio)-1-oxopropyl]maytansine;Maytansine, N2'-deacetyl-N2'-[3-(methyldithio)-1-oxopropyl]-;4,24-Dioxa-9,22-diazatetracyclo[19.3.1.1 10,14.03,5]hexacosane,maytansine deriv.;maytansinoid derivative with ADC linker. Maytansine or mertansine or emtansine derivative
CBNumber:
CB03139071
Molecular Formula:
C36H50ClN3O10S2
Molecular Weight:
784.38
MOL File:
138148-68-2.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:54:57
Request For Quotation

DM1-Sme Properties

Boiling point 957.1±65.0 °C(Predicted)
Density 1.34±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO:12.0(Max Conc. mg/mL);15.3(Max Conc. mM)
DMF:16.0(Max Conc. mg/mL);20.4(Max Conc. mM)
DMF:PBS (pH 7.2) (1:5):0.16(Max Conc. mg/mL);0.2(Max Conc. mM)
form A crystalline solid
pka 9.82±0.70(Predicted)
color Off-white to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS08
Signal word  Danger
Hazard statements  H303-H312-H315-H319-H361-H372-H317-H351-H335-H336-H412
Precautionary statements  P501-P273-P272-P260-P270-P202-P201-P271-P264-P280-P312-P337+P313-P305+P351+P338-P362+P364-P333+P313-P302+P352+P312-P304+P340+P312-P403+P233-P405

DM1-Sme Chemical Properties,Uses,Production

DM1-Sme Preparation Products And Raw materials

Raw materials

Preparation Products

Mertansine

DM1-Sme Suppliers

Global( 55)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32835 60 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8474 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686 China 2977 58 Inquiry
Hefei Hirisun Pharmatech Co., Ltd. +86-0551-62678551 +86-15056975894 China 190 55 Inquiry
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 60
BOC Sciences 58
TargetMol Chemicals Inc. 58
Zhejiang J&C Biological Technology Co.,Limited 58
InvivoChem 58
Wuhan Topule Biopharmaceutical Co., Ltd 58
Aladdin Scientific 58
Amadis Chemical Company Limited 58
Shanghai Rechem science Co., Ltd. 58
Hefei Hirisun Pharmatech Co., Ltd. 55
DM1-Sme N2'-Deacetyl-N2'-[3-(methyldithio)-1-oxopropyl]maytansine AP3 Intermidate 2 CS-2715 DM1-SME; DM1-SSME; MAYTANSINOID DERIVATIVE WITH ADC LINKER. MAYTANSINE OR MERTANSINE OR EMTANSINE DERIVATIVE; N2'-DEACETYL-N2'-[3-(METHYLDITHIO)-1-OXOPROPYL]MAYTANSINE. DM1-SSMe maytansinoid derivative with ADC linker. Maytansine or mertansine or emtansine derivative Maytansine, N2'-deacetyl-N2'-[3-(methyldithio)-1-oxopropyl]- 4,24-Dioxa-9,22-diazatetracyclo[19.3.1.1 10,14.03,5]hexacosane,maytansine deriv. (14S,16S,32S,33S,2R,4S,10E,12E,14R)-86-Chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl N-methyl-N-(3-(methyldisulfaneyl)propanoyl)-L-alaninate MaytansinoidDM4Impurity6 1H-Inden-2-ol,1-amino-2,3-dihydro-,(1R,4S)- Microtubule/Tubulin,ADC Payload,anti-tumor activity,tumor cell,DM1 SMe,DM1-SMe,inhibit,Inhibitor,maytansinoid,ADC Cytotoxin,DM-1-SMe,antibody-drug conjugate,DM1SMe (1S,2R,3S,5S,6R,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.11?,1?.03,?]hexacosa-10,12,14(26),16,18-pentaen-6-yl (2S)-2-[N-methyl-3-(methyldisulfanyl)propanamido]propanoate 138148-68-2 C36H50ClN3O10S2