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N-PHENYL-7-(HYDROXYIMINO)CYCLOPROPA[B]CHROMEN-1A-CARBOXAMIDE

N-PHENYL-7-(HYDROXYIMINO)CYCLOPROPA[B]CHROMEN-1A-CARBOXAMIDE Structure
CAS No.
1161205-27-1
Chemical Name:
N-PHENYL-7-(HYDROXYIMINO)CYCLOPROPA[B]CHROMEN-1A-CARBOXAMIDE
Synonyms
PHCCC;N-PHENYL-7-(HYDROXYIMINO)CYCLOPROPA[B]CHROMEN-1A-CARBOXAMIDE;(1aS,7E,7aS)-7-hydroxyimino-N-phenyl-1,7a-dihydrocyclopropa[b]chromene-1a-carboxamide;(1aS,7E,7aS)-7,7a-Dihydro-7-(hydroxyimino)-N-phenylbenzo[b]cyclopropa[e]pyran-1a(1H)-carboxamide;Benzo[b]cyclopropa[e]pyran-1a(1H)-carboxamide, 7,7a-dihydro-7-(hydroxyimino)-N-phenyl-, (1aS,7E,7aS)-
CBNumber:
CB0450874
Molecular Formula:
C17H14N2O3
Molecular Weight:
294.3
MOL File:
Mol file
Modify Date:
2022/12/21 16:56:50
Request For Quotation

N-PHENYL-7-(HYDROXYIMINO)CYCLOPROPA[B]CHROMEN-1A-CARBOXAMIDE Properties

Boiling point 579.1±50.0 °C(Predicted)
Density 1.41±0.1 g/cm3(Predicted)
storage temp. Store at RT
pka 10.79±0.40(Predicted)

N-PHENYL-7-(HYDROXYIMINO)CYCLOPROPA[B]CHROMEN-1A-CARBOXAMIDE Chemical Properties,Uses,Production

Biological Activity

Group I metabotropic glutamate receptor antagonist (IC 50 ~ 3 μ M); 67 times more potent than (S)-4-carboxyphenylglycine ((S)-4-Carboxyphenylglycine). Also a positive allosteric modulator for mGlu 4a ; potentiates L-AP4-mediated inhibition of striatopallidal synaptic transmission in vitro . Displays antiParkinsonian effects in rats in vivo .

N-PHENYL-7-(HYDROXYIMINO)CYCLOPROPA[B]CHROMEN-1A-CARBOXAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

N-PHENYL-7-(HYDROXYIMINO)CYCLOPROPA[B]CHROMEN-1A-CARBOXAMIDE Suppliers

Global( 40)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Fluorochem Ltd (01457) 868921 (4 lines) United Kingdom 6383 65 Inquiry
3B Scientific Corporation 847.281.9822 United States 6744 47 Inquiry
MOLEKULA Ltd. +44 (0) 1747 831066 United Kingdom 6152 66 Inquiry
CARBONE SCIENTIFIC CO.,LTD +44(0)870 486 8629 United Kingdom 6682 30 Inquiry
Tocris Bioscience +44 (0) 117 916 3333 United Kingdom 5729 77 Inquiry
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 China 15848 69 Inquiry
Shanghai Yupu Chemical Technology Co., Ltd. 021-61842042 18964386050 CHINA 1328 58 Inquiry
Shanghai Han-Xiang Chemical Co., Ltd. +86 (21) 5027-2946, +86 13818785766 China 1039 50 Inquiry
Boao Pike 010-57798038 15652371397 CHINA 6629 58 Inquiry
Shanghai Machine Pure Industrial Co., Ltd. 021-54720761 13524933993 CHINA 6800 58 Inquiry
Supplier Advantage
Fluorochem Ltd 65
3B Scientific Corporation 47
MOLEKULA Ltd. 66
CARBONE SCIENTIFIC CO.,LTD 30
Tocris Bioscience 77
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Shanghai Yupu Chemical Technology Co., Ltd. 58
Shanghai Han-Xiang Chemical Co., Ltd. 50
Boao Pike 58
Shanghai Machine Pure Industrial Co., Ltd. 58
N-PHENYL-7-(HYDROXYIMINO)CYCLOPROPA[B]CHROMEN-1A-CARBOXAMIDE PHCCC (1aS,7E,7aS)-7,7a-Dihydro-7-(hydroxyimino)-N-phenylbenzo[b]cyclopropa[e]pyran-1a(1H)-carboxamide (1aS,7E,7aS)-7-hydroxyimino-N-phenyl-1,7a-dihydrocyclopropa[b]chromene-1a-carboxamide Benzo[b]cyclopropa[e]pyran-1a(1H)-carboxamide, 7,7a-dihydro-7-(hydroxyimino)-N-phenyl-, (1aS,7E,7aS)- 1161205-27-1 Glutamate