Betamethasone Impurity 8

Betamethasone Impurity 8 Structure
CAS No.
1203841-38-6
Chemical Name:
Betamethasone Impurity 8
Synonyms
6α-Bromo Betamethasone;6α-Bromo Betamethasone;Betamethasone Impurity 8;Betamethasone Impurity 19;Betamethasone 6 a bromo analog;Betamethasone 6alpha-Bromo Impurity;(6α,11β,16β)-6-Bromo-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione;Pregna-1,4-diene-3,20-dione, 6-bromo-9-fluoro-11,17,21-trihydroxy-16-methyl-, (6α,11β,16β)-;6α-Bromo Betamethasone/Betamethasone 6alpha-Bromo Impurity/6-Bromo-9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione;(6S,8S,9R,10S,11S,13S,14S,16S,17R)-6-Bromo-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
CBNumber:
CB04800835
Molecular Formula:
C22H28BrFO5
Molecular Weight:
471.36
MOL File:
1203841-38-6.mol
Modify Date:
2023/4/23 13:52:06

Betamethasone Impurity 8 Properties

Melting point >149°C (dec.)
Boiling point 599.0±50.0 °C(Predicted)
Density 1.52±0.1 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
pka 12.00±0.70(Predicted)
form Solid
color White to Off-White

Betamethasone Impurity 8 Chemical Properties,Uses,Production

Uses

(6α,11β,16β)-6-Bromo-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione is a derivative of Betamethasone (B327000), a glucocorticoid used as an anti-inflammatory agent.

Betamethasone Impurity 8 Preparation Products And Raw materials

Raw materials

Preparation Products

Betamethasone Impurity 8 Betamethasone Impurity 19 (6α,11β,16β)-6-Bromo-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione 6α-Bromo Betamethasone Betamethasone 6alpha-Bromo Impurity Pregna-1,4-diene-3,20-dione, 6-bromo-9-fluoro-11,17,21-trihydroxy-16-methyl-, (6α,11β,16β)- 6α-Bromo Betamethasone/Betamethasone 6alpha-Bromo Impurity/6-Bromo-9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione Betamethasone 6 a bromo analog (6S,8S,9R,10S,11S,13S,14S,16S,17R)-6-Bromo-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one 6α-Bromo Betamethasone 1203841-38-6